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A supermodel and a former British government advisor have invested in separate ventures aiming to sell non-alcoholic beverages that mimic the pleasant effects of alcohol without the hangovers or health dangers. Robert Joseph wonders whether they are part of the shape of things to come. No one who has been following the beverage sector can have failed to notice the explosive growth in interest in no- and low-alcohol. Anybody who can create drinks with zero alcohol that genuinely taste as good as the wines, beers and spirits traditionally consumed throughout the world will have found a holy grail, and potentially made a lot of money. But there is more than one grail. Taste is far from the only reason people choose to consume alcohol. They also want the buzz they get from these products. In other words, the mood at the end of the evening will be very similar to the way it was at the beginning. Unless someone can come up with a way of creating the buzz without using alcohol or other drugs. And there are alternatives. Among the more interesting is one called Alcarelle proposed in the Britain by David Nutt, professor of neuropsychopharmacology at Imperial College London. Nutt had a brief moment of fame in as government's chief drug adviser under prime minister Tony Blair, when he declared that alcohol was more dangerous than ecstasy or LSD. That comment cost him his job. As Nutt and colleagues explain in a research paper published last year called Functional Alternatives to Alcohol , booze increases the activity of gamma-aminobutyric acid GABA a powerful inhibitory neurotransmitter to be found in all mammalian brains. A blood-alcohol concentration of 0. At above 0. In addition, alcohol also influences other neurotransmitters such as dopamine and endorphins, which can lead to addiction. The principle behind the product is far from new. It has long been used in medicine, for example in benzodiazepines, which are both used to treat anxiety and insomnia, and notoriously abused as drugs. A comparatively harmless muscle relaxant called baclofen is also based on the GABA receptor principle and is already approved in Italy and Austria to treat alcohol dependence. But not for use in beverages. Six years later, she went on to create Noughty, a zero-alcohol sparkling wine that has become a bestseller on both sides of the Atlantic. Nootropic drinks and snacks first began to attract interest around a decade ago with the revelation that Silicon Valley and Wall Street high-flyers who might once have been fuelled by cocaine or legally-prescribed smart drugs such as Ritalin, were now relying on synthetic derivatives of GABA called racetams. The first and most famous of these was Piracetem which was synthesised by a Romanian scientist called Corneliu Giurgea in Batchelor and Hadid may appear to have beaten David Nutt to the starting line but, while waiting for Alcarelle to get its official green light, he has launched a beautifully-packaged and premium-price competitor to their drinks called Sentia, based on 13 different plant extracts. Journalists who have sampled Sentia have reported feeling the buzz. On the other hand, he could not dismiss the possibility of all these symptoms being explicable by the placebo effect. The same might be said of High Rhode, which makes it interesting to read through some of the Amazon reviews it has received. Several purchasers seemed to experience little buzz. And it does have a noticeable pleasant intoxicating effect. Meh was not the only person to dislike the flavour. Assuming the efficacy is proven, flavour, packaging and price are all issues that may be addressable, but other questions remain. Both Sentia and Kin Euphorics come with warnings against use before driving or consumption while pregnant. Time will tell. Perhaps non-alc drinks with buzz will be one of those short-lived, quirky products that are only ever remembered by people in the know. Meininger's International will be hosting a conference on low and non-alcohol wine at ProWein, on Sunday at 11am. All readers will be welcome. Robert Joseph wonders whether the focus on using sophisticated technology to remove alcohol from wine hasn't distracted producers from making beverages that taste good. And maybe more like the kind of wine most people really want to drink. Half of all profits will go to Alzheimer's Research. Reading time: 5m 55s. Sentia - non alcoholic, but with a buzz. Where's the buzz? When developing Alcarelle, Nutt and his colleagues had three goals: The new compound must react precisely with the desired receptors and not trigger any other receptors that could, for example, lead to addiction. There must be an upper limit to the effect to avoid overdoses. The compound must be based on proven compatible molecular structures to prevent physical counter-reactions. Reading time: 8m 30s. Nootropic drinks Nootropic drinks and snacks first began to attract interest around a decade ago with the revelation that Silicon Valley and Wall Street high-flyers who might once have been fuelled by cocaine or legally-prescribed smart drugs such as Ritalin, were now relying on synthetic derivatives of GABA called racetams. A supermodel gets involved High Rhode on amazon. Questions remain Assuming the efficacy is proven, flavour, packaging and price are all issues that may be addressable, but other questions remain. Watch this space Reading time: 3m. Latest Articles. End of an Era? Insights Oct Sponsored reports Oct 9. Languedoc: Going From Red to White. With a Few Exceptions.

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Neustadt buying Ecstasy

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Neustadt buying Ecstasy