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Cola and Honey: Exploring food riddles in rhythm disturbances

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Drinking excessive amounts of cola and eating honey made from the pollen of Rhododendrons can cause unusual syncope fainting and symptoms of arrhythmia. Athens, Greece, 25 June Naima Zarqane and Prof. Nadir Saoudi, from the Princess Grace Hospital Centre, Monaco, report how excessive consumption of cola drinks can result in marked potassium loss hypokalemia , QT prolongation on ECGs and potentially life threatening arrhythmias. In the abstract the team describe the case of a 31 year old woman admitted to hospital for traumatic syncope. Once other problems had been excluded including a family history of sudden death, digestive symptoms, and metabolic or hormonal abnormalities , tests revealed the patient had blood potassium levels of 2. Normal blood potassium levels range between 3. When they took a medical history the clinicians discovered that since the age of 15 years the patient had exclusively replaced water with cola beverages. A literature search revealed six other case studies where excessive cola consumption could be related to adverse medical conditions including rhabdomyolysis damaged skeletal muscle tissue , arrhythmias, and even one death related to Torsades de pointes a form of ventricular tachycardia that can degenerate into ventricular fibrillation. There are two potential explanations for the connection between cola consumption and low blood potassium level the authors say. Additionally, caffeine in the cola is also likely to have an effect on the loop of Henle in the kidneys where it reduces the amount of potassium that is reabsorbed. In the heart reduced extracellular potassium can inhibit the potassium current in ion channels and delay ventricular repolarisation that may in turn promote arrhythmias. In a further study it would be helpful to explore whether there are differences in blood levels of potassium between people who had high cola intakes, and people who did not consume the drink, he says. Excessive drinking of cola and other sugary beverages is likely to have additional adverse cardiovascular effects. Surface ECGs revealed both patients to have complete atrioventricular block and atrial flutter with slow ventricular responses. When a history was taken both father and son reported that their breakfasts over the past three mornings had included high amounts of honey from the Black sea region of Turkey. Mad honey poisoning occurs after people consume honey contaminated with grayanotoxin, a chemical contained in nectar from the Rhododendron species ponticum and luteum. Grayanotoxin is a neurotoxin that binds to the sodium channels in the cell membrane, maintaining them in an open state and prolonging depolarisation. Mad honey poisoning generally lasts no more than 24 hours, with symptoms of the mild form including dizziness, weakness, nausea, vomiting, excessive perspiration, hypersalivation and paraesthesia. Symptoms of the more severe form include syncope, seizures, complete atrioventricular block and even fatal tachyarrhythmias due to oscillatory after potentials. While no specific antidote exists for grayanotoxin poisoning mild cases can be treated with atropine and selective M2 muscarinic receptor antagonists; while for the more severe form treatment options include temporary pacemaker implantation, and vasopressor agents. The possibility of honey poisoning, says Dr. Turk, should always be considered in previously healthy patients admitted with unexplained hypotension, bradycardia and other rhythm disturbances. The condition occurs most frequently in people who have consumed honey from the Black sea region of Turkey, a major bee keeping area that is also the native habitat of Rhododendron ponticum and luteum. The symptoms of both father and son resolved without the need for any medications and they were discharged from hospital on the fourth day. When their honey was sent away for melissopalynology, analysis of the pollen contained in honey the result revealed it did indeed contain pollen from the Rhododendron species. Scientific Programme Online. Its mission is to reduce the burden of cardiovascular disease in Europe. Its aim is to improve the quality of life of the European population by reducing the impact of cardiac arrhythmias and reducing sudden cardiac death. Our mission: To reduce the burden of cardiovascular disease. Help centre Contact us. All rights reserved. Did you know that your browser is out of date? To get the best experience using our website we recommend that you upgrade to a newer version. Learn more. Show navigation Hide navigation. Sub menu. Cola and Honey: Exploring food riddles in rhythm disturbances 25 Jun Drinking excessive amounts of cola and eating honey made from the pollen of Rhododendrons can cause unusual syncope fainting and symptoms of arrhythmia. Topic s : Arrhythmias and Device Therapy. Anyone buying honey from Turkey should first consume a small amount and leave it a few days before eating any more to check that they do not experience strange side effects. Syncope and hypokalemia with mild long term mild cola consumption. FP Syncope Poster Session. Mad honey: so sweet pass out. Arrhythmias Poster Session. About the ESC. Press and Media. Follow us. Need help?

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