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BZP is banned in a few countries, including the USA, Republic of Ireland, Australia and New Zealand, but is available on a more or less restricted basis in many jurisdictions. A range of other piperazine derivatives have also been sold as ingredients in party pills, and many of these branded "proprietary blends" have subsequently been sold in countries around the world. Piperazine derivatives sold in this way include BZP, TFMPP, MeOPP, pFPP and several others. mCPP has rarely been sold as a party pill ingredient due to its tendency to cause migraine headaches. These piperazines are usually mixed with other ingredients such as caffeine, 5-HTP, Oxedrine (which has close effects to ephedrine),[1] Camelia sinensis and a range of vitamins, minerals, amino acids and binders to make party pills. In countries such as New Zealand where BZP and related piperazines have been recently made illegal, there is now increasing commercial interest in piperazine free "party pills" which are purported to produce similar effects with ingredients that will circumvent the ban.
Common active ingredients (among many others) include caffeine, theobromine, other stimulant alkaloids, octopamine, blue lotus extract (Nymphaea caerulea), natural sources of the LSD precursor and weak psychedelic agent lysergic acid amide (illegal in many countries), passionflower (sedative which contains monoamine oxidase inhibitors), Citrus aurantium (contains small amounts of the stimulant synephrine), glaucine (plant derived compound usually used as cough medicine), and geranamine (alkylamine compound found in geranium oil). Party pills and their legal status are often in the news. Matt Bowden, one of the original distributors of such pills[2] was interviewed when issues involving party pills arose in the media. A clinical trial by ClubStargate for a pill named Ease was suspended because it contained methylone, which was claimed by the Ministry of Health to fall under New Zealand controlled drug analogue laws (although this was never proven in court). New Zealand has classified BZP-based party pills as a "Restricted Substance" by the Misuse of Drugs Act and restricted to those over 18 years.