Major Recall of Liquid Drugs, Supplements Due to Potential Bacterial Contamination PharmaTech announced a voluntary recall of all liquid products due to a potential risk of contamination with Burkholderia cepacia. If a product contaminated with B. cepacia is administered, infections can develop in patients with compromised immune systems and in patients with chronic lung conditions (eg, cystic fibrosis). Some of these infections may be serious and/or life-threatening in patient populations that are at risk. The recall impacts all liquid products from October 20, 2015 through July 15, 2016. Drug products affected by the recall include: Additionally, various dietary supplement products from Rugby, Major, Bayshore, and Metron are impacted by the recall: Poly-Vita Drops with Iron Polyvitamin liquid with Iron The Company is notifying its distributors via a recall letter and is arranging for return of all recalled products. Anyone in possession of the recalled products should discontinue all use and dispensing immediately.
For more information visit FDA.gov. Scroll down to see the next article Memory and Brain Support Vital to health and well-being In extra virgin olive oil 4,000 IU per serving 4,000 IU 15 ml Liquid Vital to health and well-being In extra virgin olive oil 4,000 IU per serving Nature's Answer Vitamin D-3 delivers 4,000 IU per serving. Vitamin D-3 is vital for many body processes, including the promotion of strong bones by assisting in calcium metabolism. Vitamin D also influences a host of key biological functions vital to health and well-being. Vitamin D is called the "Sunshine Vitamin" because it's produced naturally by the body after exposure to sunlight. Nature's Answer Vitamin D-3 drops in extra virgin olive oil are free of salt, wheat, corn, yeast, sugar, milk, preservatives and fish. Serving Size 2 drops Servings Per Container: 300 Vitamin D3 (as cholecalciferol)** *Percent Daily Values are based on a 2,000 calorie diet. †Daily Value not established.
Other Ingredients: Extra virgin olive oil. Suggested Use: As a dietary supplement take two (2) drops daily or as directed by your healthcareMay be mixed with food or liquids, such as water or juice. CAUTION: Keep out of reach of children. Not for use by children under 3 yrs. of age. Do not use if safety seal is damagedIf pregnant, nursing or on medication, consult with your healthcare practitioner. Salt-free, wheat-free, corn-free, yeast-free, sugar-free, milk-free, preservative-free, Nature's Answer Vitamin D-3 Drops Reviews Risk-Free Purchase Guarantee on Nature's Answer Vitamin D-3 DropsClick here to request a new size. Indications: Vitamin D Supplementation or Replacement Contraindications: Vitamin D Supplementation Preparations: Dietary and Supplement Sources Signs: Vitamin D Deficiency Signs: Vitamin D Toxicity (related to Hypercalcemia) Dosing (higher than current RDA) Dosing: Supplementation in Infants and Children under age 2 years
Dosing: Children with Vitamin D Deficiency (Rickets) Dosing: Adults with Vitamin D Deficiency Efficacy: Vitamin D in Osteoporosis Prevention Extra: Related Bing Images Step 1a: Start with 7-DehydrocholesterolSkin exposure to sunlight or other ultraviolet light (290-315 nm of UV-B radiation)This pathway represents 90% of Vitamin D synthesis in humans Step 1b: Start with Dietary Vitamin D2 or D3Proceed to step 2 (bypasses sunlight-mediated synthesis pathway)Typically represents only 10% of Vitamin D source (unless specifically supplemented) Step 2: Cholecalciferol (Vitamin D3)Metabolized in liver by Vitamin D3-25 hydroxylase Step 3: CalcidiolMetabolized in Kidney by 25-OH-D3-1a hydroxylase Step 4: Calcitriol (active form of Vitamin D) See Serum Calcium for calcium metabolism SourcesVitamin D synthesized in skin after exposed to sunAbsorbed from Small Intestine Vitamin D circulates in blood as Calcidiol Vitamin D Deficiency seen in:Homebound elderlyInhabitants of Northern States
Vitamin D Deficiency related conditionsChildren: RicketsAdults: Osteoporosis IV. Indications: Vitamin D Supplementation or Replacement V. Contraindications: Vitamin D Supplementation Granulomatous disease (e.g. Tuberculosis, Sarcoidosis) VI. Preparations: Dietary and Supplement Sources Fish (Vitamin D3, most in fatty fish)Salmon (450 IU per 3 oz)SardinesFish oilsTuna (150 IU per 3 oz) Liver and other organ meats Vitamin D Fortified Milk (USA) contains 100 IU per cup Multi-Vitamin Contains 400 IU Vitamin D per tablet VII. Signs: Vitamin D Deficiency See Vitamin D Deficiency VIII. Signs: Vitamin D Toxicity (related to Hypercalcemia) Vascular calcinosis or nephrocalcinosis IX. Dosing (higher than current RDA) Children and Adolescents: 400 IU per day Adults Age 18-50 years: 400-800 IU per day Adults Age >50 years or Osteoporosis:Southern regions: 800-2000 IU per dayNorthern climates: 2000 IU per day may be required
Expect a 0.4 ng/ml increase for every 40 IU daily of Vitamin DExpect 4 ng/ml increase from 400 IU dailyExpect 40 ng/ml increase from 4000 IU daily Vitamin D is fat soluble and is best absorbed with fat in the meal X. Dosing: Supplementation in Infants and Children under age 2 years IndicationsSee Vitamin D Deficiency for risk factorsBreastfed InfantsChildren and adolescents consuming <1 Liter (34 oz) Vitamin D Fortified milk daily Supplements with daily dose of 1 drop (equivalent to 400 IU) for age under 2 yearsCarlson Baby D Drops Supplements with daily dose of 1 ml (equivalent to 400 IU) for age under 2 yearsEnfamil Poly-Vi-Sol Multivitamin Supplement dropsEnfamil Poly-Vi-Sol Vitamins A, C and D with IronSunlight Vitamins Just D Infant Vitamin DropsTwinlab Infant Care Multivitamin Drops with DHA ReferencesCasey (2010) Am Fam Physician 81(6): 745-50 [PubMed] XI. Dosing: Children with Vitamin D Deficiency (Rickets) Ergocalciferol (D2, Calciferol)Dose: 25-125 mcg (1-5000 IU) PO/IM for 6-12 weeks
Cholecalciferol (D3, 40,000 IU/mg)Option 1: 125-250 mcg (5-10,000 IU) PO for 3 monthsOption 2: 15,000 mcg (600,000 IU) divided qid x1 day Dihydrotachysterol (DHT, 120,000 IU/mg)Option 1: 500 mcg (0.5 mg) for single dose orOption 2: 13-50 mcg PO per day until resolved ReferencesKhatib (2005) Consultant Pediatrician 4:33-9 [PubMed] XII. Dosing: Adults with Vitamin D Deficiency Mild (Serum 25-hydroxyvitamin D 8-15 ng/ml)Calcium 1200 to 1500 mg orally dailyVitamin DOption 1: Vitamin D 50,000 IU PO weekly for 8 weeks (repeat another course if Vitamin D <30 ng/ml)Option 2: Vitamin D 1000 IU daily per every 10 ng/ml shortfall in addition to maintenance for 6 weeksExample: Vitamin D 10 ng/ml - take 2000 IU replacement in addition to 1000 IU maintenance dailyOption 3: Vitamin D 20-25 IU/kg IV daily (parenteral for hospitalized patients)Maintenance after acute replacement: Vitamin D 800-1000 IU PO daily Severe (Serum 25-hydroxyvitamin D <8 ng/ml)Vitamin D 50,000 IU orally daily for 1-3 weeksThen maintain as mild deficiency doses above Monitoring Vitamin D level at 6-8 weeks after starting therapyGoal 25-Hydroxyvitamin D >30-40 ng/mlStorage of Vitamin D does not start until 40 ng/ml
XIII. Efficacy: Vitamin D in Osteoporosis Prevention Dutch Study of 348 women over age 70 yearsGiven Vitamin D 400 IU or PlaceboVitamin D Group had greater BMD at 2 yearsGreater femoral neck Bone Mineral DensityPlacebo group had decreased Bone Mineral DensityNo change in femoral trachanter or distal radius BMD ReferencesOoms (1995) J Clin Endocrinol Metab 80:1052-8 [PubMed] Holick (2007) N Engl J Med. 357(3):266-81 [PubMed] Schneider (2006) Curr Opin Endocrinol Diabetes 13(6): 483-90 [PubMed] Norman (2007) J Steroid Biochem Mol Biol 103(3):204-5 [PubMed] Images: Related links to external sites (from Bing) Related Studies (from Trip Database) Open in New Window , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , LP31696-5, LP15553-8, MTHU010601, LA18889-8 , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,
Vitamin D helps your body absorb calcium, which your bones need to grow. A lack of vitamin D can lead to bone diseases such as osteoporosis or rickets. Vitamin D also has a role in your nerve, muscle, and immune systems. You can get vitamin D in three ways: through your skin, from your diet, and from supplements. Your body forms Vitamin D naturally after exposure to sunlight. However, too much sun exposure can lead to skin aging and skin cancer. So many people try to get their vitamin D from other sources. Vitamin D-rich foods include egg yolks, saltwater fish, and liver. Some other foods, like milk and cereal, often have added vitamin D. You can also take vitamin D supplements. Check with your health care provider to see how much you should take. People who might need extra vitamin D include People with dark skin People with certain conditions, such as liver diseases, cystic fibrosis and Crohn's disease People who are obese or have had gastric bypass surgery