Golden Luminescence Infusion Mask 4.554 (4 customer reviews)$3,999.00Availability:In Stock- same day shippingSign up today to receive $50 off your first purchase of $200 or more.Plus, get the inside scoop on exclusive offers sent directly to you. Maybe Linus Pauling was on to something after all. Decades ago the Nobel Prize–winning chemist was relegated to the fringes of medicine after championing the idea that vitamin C could combat a host of illnesses, including cancer. Now, a study published online today in Science reports that vitamin C can kill tumor cells that carry a common cancer-causing mutation and—in mice—can curb the growth of tumors with the mutation. If the findings hold up in people, researchers may have found a way to treat a large swath of tumors that has lacked effective drugs. "This [could] be one answer to the question everybody's striving for," says molecular biologist Channing Der of the University of North Carolina, Chapel Hill, one of many researchers trying to target cancers with the mutation.
The study is also gratifying for the handful of researchers pursuing vitamin C, or ascorbic acid, as a cancer drug. Maybe people will finally pay attention," says vitamin C researcher Mark Levine of the National Institute of Diabetes and Digestive and Kidney Diseases. In 1971, Pauling began collaborating with a Scottish physician who had reported success treating cancer patients with vitamin C. But the failure of two clinical trials of vitamin C pills, conducted in the late 1970s and early 1980s at the Mayo Clinic in Rochester, Minnesota, dampened enthusiasm for Pauling’s idea. Studies by Levine’s group later suggested that the vitamin must be given intravenously to reach doses high enough to kill cancer cells. A few small trials in the past 5 years—for pancreatic and ovarian cancer—hinted that IV vitamin C treatment combined with chemotherapy can extend cancer survival. But doubters were not swayed. "The atmosphere was poisoned" by the earlier failures, Levine says. A few years ago, Jihye Yun, then a graduate student at Johns Hopkins University in Baltimore, Maryland, found that colon cancer cells whose growth is driven by mutations in the gene KRAS or a less commonly mutated gene, BRAF, make unusually large amounts of a protein that transports glucose across the cell membrane.
The transporter, GLUT1, supplies the cells with the high levels of glucose they need to survive. GLUT1 also transports the oxidized form of vitamin C, dehydroascorbic acid (DHA), into the cell, bad news for cancer cells, because Yun found that DHA can deplete a cell’s supply of a chemical that sops up free radicals. Because free radicals can harm a cell in various ways, the finding suggested “a vulnerability” if the cells were flooded with DHA, says Lewis Cantley at Weill Cornell Medicine in New York City, where Yun is now a postdoc. Cantley’s lab and collaborators found that large doses of vitamin C did indeed kill cultured colon cancer cells with BRAF or KRAS mutations by raising free radical levels, which in turn inactivate an enzyme needed to metabolize glucose, depriving the cells of energy. Then they gave daily high dose injections—equivalent to a person eating 300 oranges—to mice engineered to develop KRAS-driven colon tumors. The mice developed fewer and smaller colon tumors compared with control mice.
Cantley hopes to soon start clinical trials that will select cancer patients based on KRAS or BRAF mutations and possibly GLUT1 status. His group’s new study "tells you who should get the drug and who shouldn't," he says. Cancer geneticist Bert Vogelstein of Johns Hopkins University, in whose lab Yun noticed the GLUT1 connection, is excited about vitamin C therapy, not only as a possible treatment for KRAS-mutated colon tumors, which make up about 40% of all colon cancers, but also for pancreatic cancer, a typically lethal cancer driven by KRAS. “No KRAS-targeted therapeutics have emerged despite decades of effort and hundreds of millions of dollars [spent] by both industry and academia,” Vogelstein says. Others caution that the effects seen in mice may not hold up in humans. But because high dose vitamin C is already known to be safe, says cancer researcher Vuk Stambolic of the University of Toronto in Canada, oncologists “can quickly move forward in the clinic." One drawback is that patients will have to come into a clinic for vitamin C infusions, ideally every few days for months, because vitamin C seems to take that long to kill cancer cells, Levine notes.
But Cantley says it may be possible to make an oral formulation that reaches high doses in the blood—which may be one way to get companies interested in sponsoring trials.“In fact even when there is not a single outward symptom of trouble, a person may be in a state of vitamin C deficiency more dangerous than scurvy itself. When such a condition is not detected, and continues uncorrected, the teeth and bones will be damaged, and what may be even more serious, the blood stream is weakened to the point where it can no longer resist or fight infections not so easily cured as scurvy.” –Food and Life Yearbook 1939, U.S. Department of Agriculture. Vitamin C has been a long-time favorite supplement for many and for very good reasons. It is the one thing that has made the whole difference for detox purposes, but it has also saved the lives of many around the world. It has regained popularity recently as a DNA protector from free radical damage in workers with severe radiation exposure at the Fukushima nuclear plant, where workers had no significant change in both free DNA and overall cancer risk when supplemented with vitamin C.
Vitamin C also helps manufacture collagen, vital for the health of all our tissues and the repair of blood vessels, teeth, joints and bones. It also helps to normalize blood pressure, heal degenerative diseases and prevent premature aging. It is vital so our immune system can fight viruses, bacteria and other microbes. Vitamin C is also important in the synthesis of brain chemicals such as our happy mood neurotransmitter – serotonin. Nobel Prize winner, Linus Pauling and Dr. Irwin Stone have helped pioneer the concept of orthomolecular medicine which uses megadose vitamin therapy – vitamin C in doses higher than those required for normal cellular functions. When taken in very high doses (10 or 100 grams or more per day, depending upon the person’s requirements and illness) vitamin C fights off serious illness. For instance, when the body is challenged by cancer, colds, toxicity or diseases, we are overwhelmed with free radical production. This is when our requirements of vitamin C increases.
Read about Vitamin C’s Historical and Miraculous Record. Mainstream medicine remains in the dark when it comes to knowledge about vitamin C despite the miraculous effects it has had on people whose prognosis was fatal. Vitamin C or ascorbic acid, is something you want to have in your medical cabinet, as it can save your life as it had done so for so many people around the world. Vitamin C is also the best thing so far for adrenal support during very stressful times and/or when we feel extremely fatigued. As a powerful water-soluble anti-oxidant that we are not capable to synthesize within our bodies, you might want to take 1 heaping teaspoon (4 grams) per day, when you first start detoxifying. During stressful times (either emotional or from illness) more doses are required, especially when you are eating a diet rich in carbs. As it happens, vitamin C and sugar use the same port entry to access our cells and when there is little to no sugar to compete, a higher percentage of vitamin C gets into the cells making our requirements shrink.
This is why our need for vitamin C goes down to the point where most people had to minimize or even eliminate it in a ketogenic diet – a diet based on animal foods and fats. And since most animals make their own vitamin C, it is possible to get enough vitamin C in a ketogenic diet without any plant foods by eating the proper parts of the animal: organs. Keep in mind that vitamin C dosage should be built up gradually, and the same is also true for lowering the dose of vitamin C, in order for our bodies to adjust to the change. Going slowly also prevents Herxheimer reactions which come when you first start detoxifying. A Herxheimer reaction is an excretion of toxins from dying microbes (i.e. yeast overgrowth), sometimes called a ‘die off’ reaction. Some say that pregnant women should not exceed 5 grams of vitamin C a day, although early pioneers on vitamin C have used very large doses for the benefit of both the mother and the baby. Large doses can cause diarrhea since excess vitamin C than your body requires doesn’t get absorbed.
In time of illness, you can gradually increase vitamin C by 2 to 4 grams each hour until your tummy starts to gargle or you have a loose stool. This is what is known as titrating doses of vitamin C. The most inexpensive vitamin C is ascorbic acid which you can get in bulk size, although other high quality forms and alkaline and better absorbed versions are available such as sodium ascorbate. If ascorbic acid gives you acidity, mix with some stevia, xylitol or a little bit of sodium bicarbonate to take the bite off. For those concerned that vitamin C will increase their blood sugar levels, well, it seems that it doesn’t, even at doses of 2 grams every 3 hours. Unfortunately, with so many medical regulations and drug protocols, vitamin C’s healing effects has remained in the back stage in a system ruled by Big Pharma. Despite this, it continues to help many around the world and it is starting to regain increasing popularity in conditions where no drug has made such a difference as vitamin C does.
Nowadays there are options that can substitute the intravenous (IV) vitamin C therapy in megadoses in the form of liposomal vitamin C which can be taken orally and made at home. If you are interested in getting the benefits of IV vitamin C in megadoses from the comfort of your home, don’t miss this relevant information! A liposome is like a bag that carries a substance into your body and its cells. It is incredibly effective at this task since it is made out of fat. As it happens, it is the same type of fat that make up cell membranes, making the job of crossing this barrier much easier. Plus, liposomes are super tiny and in that way, they can go through every teensy crack of our cell barriers. In order to achieve an effective megadose vitamin C dose – for instance, to kill cancer cells – you need to achieve a vitamin C blood level of around 250-350 mg/dl. An average person will typically have around 1 mg/dl on a fairly decent diet. After a 25 to 50 grams IV vitamin C therapy delivered in about a 90-minute period, the blood level is in the 200 to 300 mg/dl range.
Reports say that 6 g of oral liposomally-carried vitamin C is equal in delivering vitamin C inside cells, where it does its work, to 50 grams of intravenous vitamin C. To make Liposomal Vitamin C, you need an ultrasonic jewelry cleaner like the one in the image. or other store of your convenience and see which size is the most practical one for you. Then you’ll need sunflower lecithin or non-GMO hexane free soy lecithin, and the vitamin C, preferably as sodium ascorbate. 3 level tablespoons of lecithin. 1 level tablespoon of sodium ascorbate. Dissolve the lecithin in 1 cup (240cc) of warm or cold water, preferably distilled. Let it soak for a couple of hours or so. It doesn’t have to clump, so using warm water is preferable (not hot!). Dissolve the sodium ascorbate in 1/2 cup warm water, preferably distilled. Pour both solutions together into the ultrasonic cleaner and mix for around 20 to 25 minutes. A loading dose, for several months, of liposomal vitamin C is likely 2,000 mg three times a day, maintenance , 1,000 mg twice daily, increasing doses and amounts when needed.
This recipe provides 12 grams (12000 mg) of Vitamin C Ascorbate at about 70% – 90% liposomal encapsulation efficiency. It will keep at room temperature for about 3 to 4 days and refrigerated, it will keep much longer. Recall that 6 grams of this stuff is the equivalent of 50 grams IV vitamin C. So you can take half the solution throughout the day for a day or two in case of illness. Wean off gradually throughout the days though, so no artificial drastic lack is perceived by the body. I’ve used 3 tablespoons of sodium ascorbate with good absorption results as well. Three tablespoons instead of one tablespoon as indicated in the above recipe will yield around 16 grams of vitamin C per cup. The absorption of the liposomal variety is about 5 times the absorption of vitamin C straight, so that is approximately 80 effective grams (IV therapy). That is a very high dose indeed! You will have to take that one cup throughout the day though, I doubt you’ll tolerate drinking in one seat without having diarrhea.