Quality Liposomal Vitamin C IntroductionI’ve built this website to help people create the very highest quality liposomal vitamin C in their own home. In my quest to discover the optimal formulation and technique I have read hundreds of research papers, reviewed patents and read or watched the accounts of many people who make their own liposomal vitamin C. I then purchased high quality laboratory equipment and sourced large quantities of ingredients to experiment with over the last eight months.I discovered that it’s possible to make liposomal vitamin C of the same or higher quality than the large manufacturers using only a blender!This website has four sections to share my research and methods:IntroductionResults of My ResearchEquipment RequiredProcessAs you’ll notice this website sells nothing (it doesn’t even have advertising) and there are no links to any liposomal vitamin C manufacturers except LivOn Labs which is used as an example of the dominant manufacturer. I created and host this website at my own expense simply to help people make better liposomal vitamin C to improve their health.
Finally, the standard disclaimer you see everywhere: I’m not a doctor, the FDA has evaluated nothing and you take your own responsibility for anything you do after reading this website!Try the new Google Patents, with machine-classified Google Scholar results, and Japanese and South Korean patents. 1. A method of making liposomes with an entrapped agent, comprising: 10. The liposome composition of claim 9 being composed of: 13. The composition of claim 9, further comprising: 14. The composition of claim 9, further comprising: 18. A method of treating scurvy, cardiovascular disease, cerebrovascular disease, cancer, age-related macular degeneration, cataracts, gout, heavy metal toxicity, or diabetes in a subject with ascorbic acid or a salt thereof entrapped in a liposome, comprising; CROSS-REFERENCE TO RELATED APPLICATIONS BRIEF DESCRIPTION OF THE DRAWINGS II. METHOD FOR PREPARING LIPOSOME COMPOSITIONS 1At least 45-50% preferably being PC such as Phospholipon 50IP, a non-GMO PC, or Alcolec PC 50.
Herbal Medicine, Healing and Cancer, Preparation of Sodium Ascorbate Entrapped Liposomes Comparison of Empirical Liposomes and LivOn Liposomes Comparison of Empirical Laboratory Liposomes and LivOn Liposomes Lypo-Spheric ™ Vitamin C (dose 4.58 g or 4 mL) (dose 6.5 g or 5.7 mL) 1An older batch tested had a particle size of 800 nm ± 450 nm. Comparison of Cold Process Liposomes to LivOn Laboratories Liposomes Comparison of Cold Process Liposomes and LivOn Liposomes Vitamin C wt % change after 50° C. incubation (% of T = 0) Liposome Stability at Room Temperature and at High Temperature Stability of liposomes stored at room temperature and at high temperature Storage at 25° C. Storage at 50° C. Comparison of Liposome Stability for Storage at 50° C. 2 2 FIG. 4 50° C. Stability of Cold Process Liposomes and LivOn Liposomes Preparation of Reduced Glutathione Entrapped Liposomes
HPLC Determination of Reduced Glutathione in Liposomes Preparation of Alpha Lipoic Acid Entrapped Liposomes HPLC Determination of Lipoic Acid Liposome Potency and Stability Stability of Na-ALA and R-ALA Liposomes Stored at Room Temperature and at 40° C. 5 wt % Na-ALA 5 wt % Na-R-ALA Stability of Na-ALA Concentration in Liposomes After Storage Na-ALA at 40 C. by HPLC (wt %) Cited PatentFiling datePublication dateApplicantTitleUS5711965Feb 21, 1996Jan 27, 1998A. Natterman & Cie. GmbhAlcoholic aqueous gel-type phospholipid composition, its use and topical preparation containing itUS6596305May 16, 1995Jul 22, 2003Elan Pharmaceuticals, Inc.Method of controlling the size of liposomesUS6713533Nov 15, 1999Mar 30, 2004Novosom AgNanocapsules and method of production thereofUS20020198258Aug 22, 2001Dec 26, 2002Brown Beverly AnnTherapeutic substances and methods of making and using sameUS20030157220Dec 23, 2002Aug 21, 2003Morello Michael J.Beverages having L-ascorbic acid with stability of color and clarityUS20090324698Oct 14
, 2005Dec 31, 2009Polymun Scientific Immunbiologische Forschung GmbhLiposomal composition comprising an active ingredient for relaxing smooth muscle, the production of this composition and the therapeutic use thereofReference1Kirby, C.J., et al, International Journal of Food Science and Technology, vol. 26, pp. 437-449, 1991.Citing PatentFiling datePublication dateApplicantTitleUS20140141066Nov 19, 2013May 22, 2014Lipo Naturals LlcEncapsulated Ascorbic Acid Composition U.S. Classification424/450, 264/4.1, 514/474International ClassificationA61P3/02, A61P3/10, A61P3/00, A61P27/12, A61K9/127, A61P35/00, A61K31/375, A61P27/02Cooperative ClassificationA61K9/127, A61K31/375, A61K31/198, A61K31/385European Classification, , ,Ascorbic Acid Supplementation: Influence of Delivery Method on Vitamin C Bioavailability and Capacity to Protect Against Ischemia-Reperfusion 1Health and Exercise Science Colorado State University Fort Collins CO United States 2Research and Development Empirical Labs Fort Collins CO United States
Intravenous administration of vitamin C has been shown to decrease oxidative stress and, in some instances, improve physiological function in adult humans. Oral vitamin C administration is typically less effective, due in part to decreased vitamin C bioavailability. The purpose of this study was to determine the efficacy of oral delivery of vitamin C encapsulated in liposomes. occasions, occurring in random order, 11 obese adults (age: 53 ± 2 years; body mass index: 34.1 ± 1.0 kg/m2 (mean ± SE)) were administered an oral placebo, or 4 g of vitamin C via: oral, oral liposomal, or intravenous delivery. area under the plasma vitamin C concentration curve, determined over 4 hours, was greatest (P < 0.001) following intravenous administration (57.0 ± 6.9 (mg/dL)·h). Liposomal vitamin C delivery (10.3 ± 0.9) evoked a greater (P = 0.002) area under the curve than oral (7.6 ± 0.4) that in turn was greater (P < 0.001) than placebo (3.1 ± 0.4). Forearm ischemia-reperfusion (20 minutes of occlusion) increased circulating thiobarbituric acid reactive substances, a marker of oxidative stress, 40 minutes post-reperfusion (P < 0.03); this increase was prevented by all of the vitamin C treatments (P > 0.05).