escherichia coli nissle 1917 probiotic buy

EcN has been used as a probiotic since its isolation. EcN has two small cryptic plasmids called pMUT1 and pMUT2. Both plasmids were fully sequenced, genetically stable, and non-transferable, and found only in EcNs. EcN has been used to treat a variety of gastrointestinal diseases without engineering. In recent years, ongoing research has focused on the genetic manipulation of EcN, using EcN as a vector for the treatment of obesity, diabetes, intestinal diseases, and other diseases. Another advantage of EcN as a chassis organism for engineered biotherapy is its wealth of knowledge on transcriptional and translational control of gene expression in Escherichia coli strains. Learn more: escherichia coli nissle 1917 probiotic buy