Researches and studies have proved that Vitamin B complex injections are more efficient than tablets, gels or liquids. This is because the digestive system, stomach acids and enzymes attack the molecular structure of B vitamins when consumed in the form of tablets or gels. But in case of injections, neither acids nor enzymes are able to attack the vitamins. This results in higher rate of absorption and retention of B vitamins with faster and effective results. Many countries use these injections as dietary supplements. Vitamin B complex injection is prescribed by many doctors and used by many individuals for an immediate boost in energy. These injections are most useful for fatigue caused due to nerve damage, diabetes, sciatica, tinnitus, effects of stress, chronic disease, B12 deficiency and a number of other conditions. The best among all the B vitamin injections is the Vitamin B-Complex 100 Injection. This is a sterile solution for intramuscular or slow intravenous vitamin injection with a blend of all B vitamins.
One ml of this B complex 100 injection contains 100 mg of thiamine, 5 mg of riboflavin, 2 mg of pyridoxine, 2 mg of pantothenic acid and 100 mg of niacin. Some of the other ingredients found in these injections include phosphate sodium, benzyl alcohol and hydrochloric acid. Hydrochloric acid is used to adjust the pH level in the injectable B complex. B complex 100 injection is mainly used for individuals with fever, severe burn, pregnancy, increased metabolism, impaired digestive tract, prolonged diseases, gastrointestinal disorders, alcoholism and various other B vitamin deficiency. Vitamin B injections are mostly used by athletes, children, vegetarians and adults over the age of 50. Injections are costlier than tablets and gels but provide faster remedy. Injectable forms are very common in many countries and are widely used in health facilities for minor common symptoms. Availability of these injections in the global market and health facilities has induced over use and misuse by consumers and providers.
Providers are making higher economic gains and better incentives by selling Vitamin B injections. Vitamin B is not actually a single vitamin but is a collection of 8 different vitamins that form the group of B vitamins. These vitamins are all water soluble which means that they can be easily transported around the body. B vitamins are present in many different foods, both natural and processed foods. The importance of B vitamins cannot be understated. Vitamins and minerals are usually required by the human body in extremely small quantities. However, the absence of these small quantities is likely to cause serious health problems to the individual. B complex vitamins promote immune system function, cell growth, metabolic function and nervous system function. Various characteristics of the individual such as energy levels, skin health, and muscle condition therefore depend on the consumption of adequate levels of B complex vitamins. The natural method for the body to be nourished by these vitamins is through the digestion and absorption of food.
In modern times, individuals have also resorted to the consumption of vitamin tablets that add extra vitamins to the diet. A significant portion of the vitamins ingested through pills and supplements is usually lost because the body cannot absorb and process these vitamins as fast as they are being digested. The benefits of vitamin consumption are therefore partially limited because of this factor. Another method of providing the body with B complex vitamins is through vitamin b complex injections. These B vitamin injections are used to directly insert these substances into the blood. The vitamin B complex injections are used to bypass the process of absorption which, as mentioned above, may not be able to handle all the vitamins that have been ingested. In theory, vitamin B complex injections therefore provide a more accurately measureable intake of B complex vitamins. This is useful for individuals who wish to have more control over their nutrition levels. There are, however, many variables associated with the use of vitamin B complex injections.
The B complex injection dosage is one factor that is extremely important in order to notice the vitamin B12 benefits. The injectable B complex dosage would vary with different person's depending on their gender, age, height and physical condition. Therefore, the B complex injection benefits would also be seen at a varied degree when individuals are compared. The use of vitamin B complex injections is essentially to derive the maximum benefits of B-complex vitamin consumption. However, there are many B complex injection side effects that are dangerous to an individual's health. Most nutrients benefit the human body when they are consumed in moderation. A lack of control in the consumption of foods causes many health problems. The extensive use of vitamin B complex injections could cause some serious side effects as the body may not be able to handle the barrage of vitamins entering its system. B complex injection side effects range from joint pains to edema. Individuals may also experience sudden variations in their metabolism and uncontrolled changes in their bodies.
People who use vitamin B complex injections for weight loss may not experience the desired changes in their bodies, especially if they continue to lead their normal lifestyles and consume their normal diets. The use of vitamin B complex injections is not completely harmful to the individual. Under medical supervision, an individual can experience many benefits from using these B complex shots. Many people suffer from vitamin deficiencies which cause health problems. The use of B complex shots can help to alleviate these problems to a certain extent. However, all of this should be done under medical supervision as the health of the individual can be properly monitored. Individuals wishing to use vitamin injections should have a valid reason for this which can only be assessed by a doctor following blood tests and health checks.A decennia long history of safe treatment In 1926 it was discovered that patients with pernicious anaemia could be saved from a certain death by eating a pound of raw liver a day.
More than 20 years later the substance that was responsible for that was isolated from liver extract: vitamin B12 or cobalamin. Since then numerous patients have been treated with high dose vitamin B12 worldwide. Usually per injection and often lifelong, as a deficiency is mostly caused by an irreversible absorption disorder. In all that time harmful effects have never been shown from overdose. No single case has been found in medical literature in the past 60 years. The Dutch National Health Council therefore decided not to determine a safe upper intake level for vitamin B12. In their report from 2003 “Voedingsnormen: vitamine B6, foliumzuur en vitamine B12” the council joined expert commissions from the American Institute of Medicine and the Scientific Committee for Human Food from the European Union, who had already reported 3 years earlier that toxicity from high dose vitamin B12 poses no real danger.1 Of course, like with any medical treatment, side effects can occur.
Acne, eczema and itching seldom occur and very rarely anaphylactic shock. Changing brands of vitamin B12, forms of B12 (cyanocobalamin vs hydroxocobalamin), or switching from injections to tablets can be a solution in those (rare) cases. Misunderstandings about blood and reference values Yet often physicians reduce injections or even stop treatment altogether out of fear of overdosing B12. The result is that many patients are left with recurring or lasting symptoms, which could be relieved by more frequent injections. After an injection the serum B12 value rises quickly, well above the upper reference value (on average 150-700 pmol/L), followed by a slow decrease. Apparently the underlying thought is that it is necessary to keep the value between the (upper and lower) reference values. However the blood level of serum B12 rises regardless of therapeutic effectiveness.2 A high serum B12 value does not mean that symptoms are treated sufficiently. This presumption can have damaging effects for patients with neurological symptoms, which can become irreversible with insufficient treatment.
Treatment based on symptoms instead of blood values The recommended treatment in the Netherlands consists of a hydroxocobalamin injection of 1mg every two months, after an initial loading dose of 10 injections in 5 to 10 weeks.3 No reference is made to the serum value or a danger of overdosing, unlike for instance in case of a vitamin D or A deficiency. The lack of danger of an overdose is further underlined by the advice to treat patients with neurological involvement with two injections a week for up to two years, if necessary. This also emphasizes that symptoms and not blood values should be used as a guideline. If serum values were decisive, even patients with neurological involvement could suffice with the maintenance dose of one injection every two months after the initial loading dose. Elevated serum B12 values in serious conditions Maybe the concern for a possible overdose is caused by the knowledge that some life-threatening diseases can be accompanied by a strong increase in the B12 blood value, in some cases to even 30 times the upper reference value.4
In blood diseases like leukemia, polycythemia vera and hypereosinophylic syndrome, the cause is often an enhanced production of the transport protein haptocorrin, to which most of the circulating B12 in blood is bound. In liver diseases such as acute hepatitis, live cirrhosis and liver cancer, elevated B12 values are often found because the liver is no longer capable of storing vitamin B12. Elevated B12 values are always cause for further testing, but of course, to the contrary, it cannot be concluded that elevated levels after B12 injections leads to serious disease. Scientific literature offers numerous examples from which it can be concluded that treatment with high dose B12 up to very high serum values is no cause for concern. Megadoses B12 as lifesaving antidote The safety of vitamin B12 treatment is further illustrated by the decennia long use of hydroxocobalamin as an antidote for cyanide poisoning, often caused by smoke inhalation. In the Netherlands ambulances, fire departments and emergency rooms have the Cyanokit at their disposal.
In life threatening situations 5 g hydroxocobalamin is given intravenously within 15 minutes, an amount that corresponds with 5 000 injections of 1 mg B12.10 Hydroxocobalamin reacts in the body with cyanide, and forms cyanocobalamin, which is excreted in urine. The serum value of B12 can rise to an average of 560 000 000 pmol/L within 50 minutes.11 If necessary this treatment is repeated within several hours, making the total dose 10 grams. The side effects that occur, like reddening of the skin and urine and changes in heart rate and blood pressure are temporary and harmless. In short: 10 000 injections a day are still not enough for an overdose of vitamin B12. Regional Disciplinary Medical Board: vitamin B12 cannot be overdosed In 2009, the Regional Disciplinary Medical Board in Eindhoven stated very clearly that an overdose is not possible: “There can be no question of an overdose of hydroxocobalamin, as the excess is excreted in urine by the kidneys and therefore cannot accumulate in the body.12 The Medical Board ruled against a patient who claimed his deteriorating health was due to the continued treatment with B12 injections.
The patient received monthly injections for 10 years. The physician was not rebuked because the patient was treated according to guidelines. A vitamin B12 deficiency can cause many different symptoms, among which are serious neurological problems. The treatment with high dose B12 injections is not only completely safe but fortunately also very effective. With the right treatment patients can recover completely. Starting straight away with treatment is essential, as is the continuing treatment in order to give the body enough B12 to fully recover. Therefore it is essential that patients are no longer exposed to the real danger of irreversible symptoms because of the imaginary fear of overdosing. 1. Voedingsnormen: vitamine B6, foliumzuur en vitamine B12. (Nutritional standards: vitamin B6, folic acid, vitamin B12) Gezondheidsraad.Publicatienr. 2003/04, Gezondheidsraad, (Dutch National Health Counsel) Den Haag 2003:130-31 2. How I treat cobalamin (vitamin B12) deficiency. Carmel R. Blood 2008;112: 2214-21
3. College voor Zorgverzekeringen. CVZ, (pharmaceutical reference book) Amstelveen 2011 4. De betekenis van een te hoge cobalamineconcentratie in het bloed. (the significance of a high cobalaminconcentration in blood) Ermens AAM, Vlasveld LTh, Van Marion-Kievit JA, Lensen CJPA, Lindemans J. NTvG 2002;146:459-64 5. Inherited disorders of folate and cobalamin transport and metabolism. In: Stanbury JB ea. (eds). Online Metabolic & Molecular Bases of Inherited Disease, The McGraw-Hill Companies, 6. Vitamin B12 metabolism and massive-dose methyl vitamin B12 therapy in Japanese patients with multiple sclerosis. Kira J, Tobimatsu S, Goto I.Intern Med 1994;33(2):82-86 7. Neuroblastoma: an evaluation of its natural history and the effects of therapy, with particular reference to treatment by massive doses of vitamin B12. Bodian M. Arch Dis Child 1963;38(202):606–19 8. Intravenous methylcobalamin treatment for uremic and diabetic neuropathy in chronic hemodialysis patients.