There were no interactions found in our database between Vitamin B12 and warfarinHowever, this does not necessarily mean no interactions exist. Vitamin B12 is in the drug class vitamins. Vitamin B12 is used to treat the following conditions: B12 Nutritional Deficiency, Pernicious Anemia, Schilling Test, Vitamin B12 Deficiency.Warfarin is a member of the drug class coumarins and indandiones. Vitamin B12 Drug InteractionsVitamin B-12 injection General Consumer InformationWarfarin Drug Interactionswarfarin tablets General Consumer InformationDrug Interactions CheckerDisclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date and complete, but no guarantee is made to that effect. Although vitamin B-12 and warfarin are not likely to interact with each other, they may negatively interact with other vitamins and supplements. Warfarin may also cause adverse side effects in some individuals, some of which can be life-threatening. Discuss the potential risks and benefits with a doctor before taking any new medication or supplement.
Vitamin B-12 is naturally present in certain foods and is also available as a dietary supplement and a prescription medication. This vitamin is necessary for proper formation of red blood cells, DNA synthesis and neurological function. Although many people get enough vitamin B-12 by eating a healthy and well-balanced diet, some may benefit from extra supplementation. Older adults or those with a certain medical condition, such as a gastrointestinal disorder or pernicious anemia, fall into this category. Strict vegetarians or vegans may also need B-12 supplements, especially during pregnancy. Vitamin B-12 does not have a tolerable upper intake level. This means side effects from the vitamin are unlikely, even when you take large doses. Warfarin is a prescription blood-thinning medication. It prevents blood clots from forming or growing. Doctors typically prescribe this medication for individuals with prosthetic heart valves, those who have suffered a heart attack and those who have certain types of irregular heartbeats.
Common side effects of the medication include gas, tiredness, pale skin, feeling cold or having chills, change in the way things taste and hair loss. It also has the potential to cause necrosis or gangrene. If you notice any unusual changes after taking this medication, call a doctor. The medication also negatively interacts with many supplements and medications, so it is essential that you tell your doctor about all of your current medications and supplements before taking warfarin.However, just because an interaction between the two is not known doesn’t mean one doesn’t exist. Always report any unusual side effects to a doctor while taking vitamin B-12 with warfarin. Anti-convulsants, chemotherapy medications, certain gout medications, H2 blockers, proton pump inhibitors, bile acid sequestrants, diabetes medications and antibiotics may interact negatively with both vitamin B-12 and warfarin. Warfarin may also negatively interact with aspirin, nonsteroidal anti-inflammatory drugs, heparin, cold or allergy medications, antidepressants, oral contraceptives, thyroid medications, painkillers, heart medications, streptokinase, urokinase and ticlopidine.
It also interacts with herbal supplements, such as bromelains, cranberry products, dong quai, garlic, ginkgo biloba, St. John’s wort, coenzyme Q10, ginseng and dashin. Whether taken with vitamin B-12 or not, warfarin may cause serious and life-threatening reactions. The medication may cause severe bleeding that can result in death. This is more likely for people over 65 years old and for those who take large doses of the medication. It is also more likely for people who regularly participate in sports or activities that may result in serious injuries. If you experience any bleeding from a cut that does not stop in the usual amount of time, call a doctor. Also call your doctor if you experience nosebleeds, bleeding from your gums, coughing up or vomiting blood, increased menstrual flow or unusual vaginal bleeding, headaches, dizziness, weakness, pain, swelling or discomfort. L Arginine & Warfarin Can You Take Vitamin B-6 if Taking Warfarin? Does a Protein Shake Interact With Warfarin?
Interactions With Niacin & Warfarin L-Arginine, Ginkgo Biloba & Ginseng The Effect of Folic Acid on Coumadin Can Too Much Vitamin B Cause Tingling? How Does Eating Cherries Affect Warfarin? Diet Supplements & Blood Thinning Calcium With Vitamin D & Blood Thinners Does Vitamin C Affect Coumadin? What Type of Foods Can I Eat While Taking Warfarin? Turmeric Effects on WarfarinCoumadin is an important prescription drug which provides tremendous health benefits for thousands of patients. As with all prescription drugs, it is important to understand the possibility of drug interaction between Coumadin and other drugs, as well as the possibility for interaction with vitamins. A prescribing physician must be apprised of all medications, including vitamin supplements, taken by a patient to avoid potentially fatal interactions with Coumadin. Coumadin is an anticoagulant drug which prevents the production of blood clots in humans. It serves to thin the blood so that it does not clot and cause heart attacks, strokes and blood clots in the veins.
Coumadin can save the lives of patients who suffer from clotting problems and is often prescribed after a significant health problem, like a stroke, to prevent further strokes from occurring. Coumadin does have side effects; however, a qualified doctor will be able to determine the proper amount of Coumadin to prescribe to reduce the side effects in each individual patient's case. Further, a doctor will balance the need for Coumadin and it's health benefits against the side effects in determining the need for taking this drug. Excessive bleeding is a typical side effect of the drug which serves to reduce clots; it will in fact cause an inability to clot if a patient cuts their face while shaving, for example. Other side effects include nausea and other stomach discomfort. Coumadin has had significant interactions with many other drugs and vitamins. Specifically, Coumadin has been found to interact negatively with such over-the-counter drugs as Tylenol, Advil and Motrin. There are many prescription drugs which cause a drug interaction which must be avoided.
Specific vitamins such as vitamin K, high levels of vitamin C, and vitamin E have been shown specifically to interact negatively with Coumadin. Some drugs and vitamins may interact negatively with Coumadin. B-12 Interactions with Coumadin As a Coumadin user, it is important to consult with a doctor when adding a vitamin supplement or a multivitamin to a health regimen. Although there are few documented cases of B12 vitamin supplements interacting with Coumadin specifically, there is significant evidence that a multivitamin containing B12 has caused negative interaction, causing a reduction in Coumadin's effectiveness. If Coumadin's effectiveness is reduced, blood clots may form which can cause heart attacks and strokes. If a reduction in effectiveness of Coumadin is found to occur, a physician may increase the dosage which can cause other adverse reactions, such as excessive bleeding. As such, it is always best to consult with a physician when adding any multivitamin, especially one containing B12, to one's diet.