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MDMA is short for 3,4-methylenedioxy-methamphetamine, more popularly known as ecstasy. Its effects last from hours from an average reported dose of tablets. Each tablet should contain anywhere from mg of MDMA, but research has shown that many of the ecstasy pills sold today actually contain more of other harmful drugs than MDMA itself. There are many others that have yet to be identified. Animal research has shown that moderate to high doses of ecstasy prove to be toxic to nerve cells that contain serotonin, causing long-lasting damage to said nerve cells. It is not uncommon for users and abusers to take ecstasy in combination with other substances, like marijuana and alcohol. Others combine ecstasy with Viagra to counter what is known to be a common side effect to taking ecstasy, that of heightened sexual appetite but diminished ability to perform. Employers may choose to request an extended drug test that includes testing for ecstasy should they have reason enough to believe that an employee may be abusing the drug. In drug screening, the cut-off level is the minimum amount of drug residue that must be found in the sample in order for the test to be positive. It is important to remember that a negative sample does not necessarily mean that it is drug-free, only that it contains a drug at a concentration that is below the established cut-off. Drugs under this class are considered dangerous. Other examples of drugs that fall under Schedule I include:. Stimulants elevate mood, promote feelings of well-being, boost energy and alertness. Paranoia and hostility eventually develop with repeated use. Stimulants are highly addictive. Hallucinogens are moderately addictive moderate psychological dependence with a high tolerance potential high physical dependence. MDMA only comes in pill or capsule form and are taken orally, but users have been known to crush the pills into powder form for snorting. They are often taken in combination with other substances that are also popular in the party scene like alcohol , marijuana , ketamine , methamphetamine and prescription drugs. Ecstasy is hardly ever pure, often cut with many different unknown toxic chemicals that make the effects unpredictable at best, rendering users unable to describe exactly what they have taken when asked by first responders in emergency situations. Examples of other ingredients so far found by researchers in ecstasy samples they have examined are cocaine , PCP and amphetamines, and those are just the ones experts know about. Sometimes, pills sold and passed off as ecstasy are not ecstasy at all but synthetic cathinones similar to those found in bath salts. For this reason, ecstasy has been used as a date-rape drug, and many consider it an aphrodisiac. The irony there is that while ecstasy increases sexual desire, it also impairs sexual performance. Men have been known to be unable to rise to the occasion during the peak effects of ecstasy, and both males and females alike find it hard to achieve orgasm. Additional side effects include dehydration and heat exhaustion, often resulting to lack of lubrication which is the top cause of condom breakage. Other people seeking to lose their inhibitions use ecstasy for this very reason, but they end up with risky behavior and doing things they would otherwise never participate in. The three brain chemicals affected by MDMA are dopamine, norepinephrine and serotonin. Ecstasy is produced by underground laboratories and sold and distributed by criminal elements on the streets. Possession is illegal and using it in any amount is considered substance abuse. These users may be completely aware of the dangers of the drug, but after physical and psychological dependence have set in, they will it nearly impossible to stop without professional help. The drug affects the regions of the brain that control sleep, aggression and perception of and response to pain. It binds to receptors in the brain which trigger the hormones that regulate these responses. This is the beginning of dependence. The user then feels compelled to use more of the drug to get back on high. The company initiated a project which trawled through thousands of corporate history documents in their Darmstadt HQ in an effort to finally set the record straight. In , German pharmaceutical giant Merck first discovered and developed ecstasy. Apparently, they were looking for a lucrative way to suppress or control the appetites of German Army soldiers, their first human guinea pigs, and were trying to develop an anorectic drug. The company ended up abandoning the project when reports of bizarre side effects started coming out. The compound was withdrawn and consigned to oblivion until it was rescued and resurrected by Alexander Shulgin in the s. This version even appeared in the official DEA website, on top of being regularly featured in news articles, textbooks and medical reports. As with most other stories, repeat it often enough for long enough and it eventually becomes accepted as gospel truth. They got right. They were hoping to help save lives, not feed their soldiers less. Merck chemists were working on methylhydrastinin, a methylated analog of hydrastinine, which they believed would be as effective. Once completed the new syntheses were secured under patents and MDMA by then called Safrylmethylamin was only a precursor substance in these patents. They did not perform pharmacological testing with MDMA until Economic reasons eventually put a stop to these tests. In , toxicological studies were finally conducted but MDMA was still not tested on humans. The appetite suppressant story in relation to MDMA may have started because from — , its analog MDA was studied for its potential as an appetite suppressor and antidepressant by Smith, Kline and French. Screening Cut-Off and Detection Time In drug screening, the cut-off level is the minimum amount of drug residue that must be found in the sample in order for the test to be positive. Request Bulk Pricing. Yemen Zambia Zimbabwe. How Often Monthly Quarterly Annually. Hair Follicle Drug Test. Urine Drug Test.

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One of the biggest donations the Pineapple Fund revealed was to MAPS, an organization working to turn MDMA into a legal, prescription drug for the treatment of PTSD. MAPS has spent the last 35 years pushing medical research into MDMA forward, and is finally closing in on FDA approval for the drug to be legally used in a psychotherapy context to help those suffering from PTSD. The last hurdle is Phase 3 clinical trials that will cost an estimated $26 million dollars.  'Prescription MDMA could be a gift to this world from the bitcoin community.' Source: The Pineapple Fund / MAPS. Tags.

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MDMA research takes a leap forward as MAPS work with the FDA to make it a prescription drug of the future.  Ongoing research shows hopeful results in the treatment of PTSD, leading many to hope it could soon be used as a prescribed therapeutic drug. MDMA takes one step closer to becoming a prescription drug in the US, as a group of scientists meet with the FDA to seek its approval for therapeutic use. MDMA has recently made a resurgence in the medical research field, with multiple studies being carried out to test effects on people with Post Traumatic Stress Disorder (PTSD), as well as other ailments. If approved, MDMA becoming a prescription drug has the potential to change the lives and wellbeing.

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