What Does Dexamethasone Do?

What Does Dexamethasone Do?

Dexamethasone

Dexamethasone is a corticosteroid that is used to treat different heath conditions such as skin diseases, allergic disorder, asthma, brain swelling, rheumatic problems and arthritis.


This drug comes in different trade names like Decadron, Dexasone, Diodex, Hexadrol, Maxidex, DexPak, Zema-Pak, etc.. It reduces the defensive reaction of the body and reduces symptoms. It can be treated with antibiotics to treat tuberculosis.


Dexamethasone is administered to the body system through the following means:


Intravenous Therapy: When the medicine in liquid form, it's administered to the body by shipping through the vein with the aid of injections or as drips. This mode of administration is known to be the fastest since it goes straight to the bloodstream.



Intramuscular treatment: Otherwise known and abbreviated as IM. This drug delivery system is carried out by the aid of injection to the muscle.


Subcutaneous Injection Therapy: is one of the many system of drug administration. It's called SC and is used to administration dexamethasone during the subcutaneous layer of the skin.


Oral Administration: This involves administering dexamethasone through the mouth.


INGREDIENTS


Dexamethasone Tablets USP usually contain either 0.5 mg, 0.75 mg, 1.5 mg, 2 mg, 4 mg, or 6 mg of dexamethasone USP. Each tablet also contain some inactive ingredients such as magnesium stearate, lactose, monohydrate, sugar, starch, FD&C Red, FD&C Yellow, Yellow Iron Oxide, D&C Yellow, and FD&C Blue.



Dexamethasone Oral Solution USP is formulated for oral administration contains 05.5 mg per 5 ml of dexamethasone USP. This oral solution contains some inactive ingredients such as propylene glycol, sorbitol solution, propylparaben, anhydrous citric acid, glycerin, disodium edetate and water.


USES OF DEXAMETHASONE/PROS


Dexamethasone has various uses in anti-inflammatory diseases, cancer, endocrine treatment, pregnancy, higher altitude illnesses, nausea and vomiting, sore throat, and veterinary applications.


Veterinary Uses:


Dexamethasone is combined with clotrimazole and marbofloxacin using a fresh name AURIZON as a remedy for severe earing infections especially in dogs.


Dexamethasone combined with dichlormethiazide may be used in the treatment of general swelling and bruising distal limbs in horses.


Anti-inflammatory diseases:


A single dose of dexamethasone in children reduces the swelling of the airway which in turns improves breathing and reduced discomfort. To put it differently, can be used for the treatment of CROUP in children. Dexamethasone given in a high dose serves as a counteract to allergic anaphylactic shock, Dexamethasone intravitreal steroid implant has been accepted by the Federal dental agency for the treatment of ocular conditions like diabetic macular edema, central retinal vein occlusion, and uveitis, dexamethasone is present in ear drops, eye drops particularly after eye surgery and present in nasal sprays. Dexamethasone is used to treat inflammatory and autoimmune conditions like rheumatoid arthritis, Idiopathic thrombocytopenic purpura. Dexamethasone is given before and or after dental surgeries such as the removal of the wisdom tooth. Dexamethasone can also be administered before antibiotics in case of bacterial meningitis to reduce inflammatory response to the murdered bacterias.


Cancer:


In brain tumors, dexamethasone can be used to suppress the progression of edema that may compress other brain structures if not attended to, dexamethasone can be utilised as a direct chemotherapeutic agent for the treatment of multiple myeloma.


Pregnancy:


Pregnancy complications may occur like premature delivery, but with the use of dexamethasone, it helps correct premature delivery by aiding in the maturation of the fetus' lungs.


Nausea and vomiting


People who have had surgery experience nausea and vomiting. Administration of dexamethasone intravenously is effective for the prevention of nausea and vomiting from recurring.


SIDE EFFECTS/CONS


Dexamethasone, like every other medication has side effects they give. The regular side effects from the ingestion of dexamethasone includes


Dizziness


Stomach upset


Sore throat


Headaches


Trouble in sleeping


Increase in appetite


Weight gain


Acne



But if the below listed serious side effects take place, contact your doctor as soon as you notice


Increased thirst and urination


Signs of infection like fever


Slow, fast or irregular heartbeat


Black stool,


Heartburns


Bone pain


Abdominal pain


Mental changes


Bleeding


Seizures



Precautions


If you have a fungal infection or allergic to this medication, please don't take it. Before taking dexamethasone, tell your doctor or pharmacist if you have:


Malaria


Thyroid disorder


Liver disease


Glaucoma or cataracts


Tuberculosis


Osteoporosis


Mental illness


Depression


Liver disease


Heart failure


High blood pressure


Herpes infection of the eyes


Diabetes


This medicine may mask signs of infection or put you at greater risk of developing very serious infections. Report any injuries or signs of infection (e.g., persistent sore throat/fever/cough, pain during urination, muscle aches) that occur during treatment.



This medicine may slow down a child's development if used for quite a while. Consult the doctor or pharmacist for additional information. See the doctor regularly so your child's height and growth could be assessed.


This drug may pass into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast- feeding.


OVERDOSE


An overdose of this medication does not pose any life-threatening issues. Long term use of high does may lead to thinning skin, increased acne or facial hair, loss of interest in sex, menstrual problems and impotence.



DRUGS THAT AFFECT DEXAMETHASONE


It's not a fantastic safe to use some specific drugs at exactly the same time because they pose a lot of risks. Ensure you tell your doctor about all the drugs you are using before taking dexamethasone for example;


Insulin or diabetes medications


Birth control pills or hormone replacement therapy


Blood thinner -- Coumadin, Jantoven


Antibiotic or antifungal medicine


Medicine to treat dementia or Parkinson disease


CONCLUSION


The activity of the world health organization in labeling dexamethasone as an important drug in the medical field has shown dexamethasone to be of relevance to the health of man and research showing that surplus dexamethasone can cause hypertension through various mechanisms show that where there is great, there is also bad. Moderation is the key to ensuring that more good than bad is what's gotten from this medication. Following the physician's prescription strictly and not self-medicating will also help to make dexamethasone us be of more good than bad.


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