Valeria Kudryavtseva
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Valeria Kudryavtseva
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Celebrities Entertainment Valeria Kudryavtseva: Top 10 Must-Know Facts About TV Show Host
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Valeria Kudryavtseva (TV Show Host) was born on the 19th of May, 1971. She was born in 1970s, in Generation X. Her birth sign is Taurus and her life path number is 6. Valeria’s birth flower is Lily of the valley and birthstone is Emerald. What does this all mean? Let’s find out!
Discover all the facts that no one tells you about Valeria Kudryavtseva below ↓
Valeria Kudryavtseva, best known for being a TV Show Host, was born in Oskemen, Kazakhstan on Wednesday, May 19, 1971. Actress and television host most well-recognized as the long time presenter of Premiya Muz-TV. She later went on to become the host of Pesnya goda and appear on Russia’s third season of Dancing with the Stars.
Family: She was married to Sergei Lenyuk from 1990 to 1992 and to Matvei Morozov from 2004 and 2007. In 2013, she married Igor Makarov. She has one son, Zhan Lenyuk. Valeria Kudryavtseva father’s name is under review and mother unknown at this time. We will continue to update details on Valeria Kudryavtseva’s family.
Education: The education details are not available at this time. Please check back soon for updates.
Dating: According to CelebsCouples , Valeria Kudryavtseva is single .
Net Worth: Online estimates of Valeria Kudryavtseva’s net worth vary. It’s easy to predict her income, but it’s much harder to know how much she has spent over the years. CelebsMoney and NetWorthStatus does a good job of breaking most of it down.
Valeria Kudryavtseva zodiac sign is a Taurus. Dates of Taurus are April 20 - May 20. People born under the Taurus zodiac sign are often incredibly dedicated, reliable and dependable. Above all things, they value their sense of security and stability. They tend to Steady, driven, tenacious, enduring, persistent, trustworthy, and patient. Although, they can be materialistic, resistant to change, indulgent, possessive, and stubborn.
The Russian tv show host has been alive for 18,625 days or 447,004 hours. There were precisely 631 full moons after her birth to this day.
Valeria Kudryavtseva was born on a Wednesday. Wednesday's children are very communicative. They're also versatile, and a bit careless.
The world’s population was 3,775,790,900 and there were an estimated year babies born throughout the world in 1971, Richard Nixon (Republican) was the president of the United States, and the number one song on Billboard 100 was "Joy To The World" by Three Dog Night.
1536 – Anne Boleyn, second wife of English King Henry VIII, is beheaded at the Tower of London on charges of adultery, incest and treason.
1643 – Massachusetts Bay, Plymouth, Connecticut and New Harbor form the United Colonies of New England.
1649 – England is declared a Commonwealth by an act of the Long Parliament making England a republic for the next 11 years.
1885 – German Chancellor Otto von Bismarck takes possession of Cameroon and Togoland.
1898 – US Congress passes the Private Mailing Card Act, allowing private publishers and printers to produce postcards, had to be labelled "Private Mailing Cards" until 1901, known as "souvenir cards".
We’re currently in process of confirming all details such as Valeria Kudryavtseva’s height, weight, and other stats. If there is any information missing, we will be updating this page soon. If you any have tips or corrections, please send them our way .
Valeria Kudryavtseva was born in the Year of the Pig. People with Chinese zodiac Pig sign are considerate, responsible, independent and optimistic. They always show generousness and mercy to endure other people's mistakes, which help them gain harmonious interpersonal relationships. Their strengths are being warm-hearted, good-tempered, loyal, honest, and gentle. But they can also be naive, gullible, sluggish, short-tempered. Their lucky numbers are 2, 5, 8 and lucky colors are yellow, grey, brown, gold.
Valeria Kudryavtseva was born in the middle of Generation X.
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Themes heist, drugs, kidnapping, coming of age
Genre drama, parody, sci-fi, comedy
Locations paris, submarine, new york
Birth Name: Valeria Lvovna Kudryavtseva
Born and residing in: Russian Federation
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Home Queen Mary, University of London School of Engineering and Materials Science Valeriya Kudryavtseva
Queen Mary, University of London | QMUL · School of Engineering and Materials Science
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My current research goals directed towards Material Science and in particular to DDSs.
A number of preclinical and clinical studies have demonstrated the efficiency of mesenchymal stromal cells to serve as an excellent base for a cell-mediated drug delivery system. Cell-based targeted drug delivery has received much attention as a system to facilitate the uptake a nd transfer of active substances to specific organs and tissues with high efficiency. Human mesenchymal stem cells (MSCs) are attracting increased interest as a promising tool for cell-based therapy due to their high proliferative capacity, multi-potency, and anti-inflammatory and immunomodulatory properties. In particular, these cells are potentially suitable for use as encapsulated drug transporters to sites of inflammation. Here, we studied the in vitro effects of incorporating synthetic polymer microcapsules at various microcapsule-to-cell ratios on the morphology, ultrastructure, cytokine profile, and migration ability of human adipose-derived MSCs at various time points post-phagocytosis. The data show that under appropriate conditions, human MSCs can be efficiently loaded with synthesized microcapsules without damaging the cell’s structural integrity with unexpressed cytokine secretion, retained motility, and ability to migrate through 8 μm pores. Thus, the strategy of using human MSCs as a delivery vehicle for transferring microcapsules, containing bioactive material, across the tissue–blood or tumor–blood barriers to facilitate the treatment of stroke, cancer, or inflammatory diseases may open a new therapeutic perspective.
Expandable metallic stent placement is often the only way to treat airway obstructions. Such treatment with an uncoated stent causes granulation proliferation and subsequent restenosis, resulting in the procedure’s adverse complications. Systemic administration of steroids drugs in high dosages slows down granulation tissue overgrowth but leads to long-term side effects. Drug-eluting coatings have been used widely in cardiology for many years to suppress local granulation and reduce the organism’s systemic load. Still, so far, there are no available analogs for the trachea. Here, we demonstrate that PLA-, PCL- and PLGA-based films with arrays of microchambers to accommodate therapeutic substances can be used as a drug-eluting coating through securely fixing on the surface of an expandable nitinol stent. PCL and PLA were most resistant to mechanical damage associated with packing in delivery devices and making it possible to keep high-molecular-weight cargo. Low-molecular-weight methylprednisolone sodium succinate is poorly retained in PCL- and PLGA-based microchambers after immersion in deionized water (only 9.5% and 15.7% are left, respectively). In comparison, PLA-based microchambers retain 96.3% after the same procedure. In vivo studies on rabbits have shown that effective granulation tissue suppression is achieved when PLA and PLGA are used for coatings. PLGA-based microchamber coating almost completely degrades in 10 days in the trachea, while PLA-based microchamber films partially preserve their structure. The PCL-based film coating is most stable over time, which probably causes blocking the outflow of fluid from the tracheal mucosa and the aggravation of the inflammatory process against the background of low drug concentration. Combination and variability of polymers in the fabrication of films with microchambers to retain therapeutic compounds are suggested as a novel type of drug-eluting coating.
Microcapsules of customized shapes offer significant advantages over spherical ones, including enhanced internalization by host cells, improved flow characteristics, and higher packing capacity. In our work, we propose a method for defined-shape polymer capsules fabrication inspired by a traditional “pelmeni” (dumplings) making process. The proposed method is based on soft lithography technique. Two different approaches were demonstrated resulting in polyelectrolyte multilayer and poly(lactic acid) (PLA) capsules both showing monodisperse size and shape distribution with about 7 μm long torpedo-like shape. The PLA capsules are described in terms of their morphology, loading of model cargo molecules, cell cytotoxicity and cell uptake. Carboxyfluorescein, FeCl2 ground crystals and Fe3O4 nanopowder were used as model cargoes for microcapsules. Capsules demonstrate core-shell structure, high loading capacity, hydrophilic molecules retention and internalization by cells without causing toxic effects. The loading efficiency of model cargo in PLA capsules was more than 80 wt%, resulting in about 40 pg of carboxyfluorescein inside each capsule. Proposed method allows unique advantages compared with alternative microencapsulation techniques, such as precise control over capsules' geometry, flexibility for the choice of active cargoes, regardless of their solubility and molecular weight and potential for triggered release mechanism.
Wound healing is a complex process and an ongoing challenge for modern medicine. Herein, we present the results of study of structure and properties of ferroelectric composite polymer membranes for wound healing. Membranes were fabricated by electrospinning from a solution of vinylidene fluoride/tetrafluoroethylene copolymer (VDF–TeFE) and polyvinylpyrrolidone (PVP) in dimethylformamide (DMF). The effects of the PVP content on the viscosity and conductivity of the spinning solution, DMF concentration, chemical composition, crystal structure, and conformation of VDF–TeFE macromolecules in the fabricated materials were studied. It was found that as PVP amount increased, the viscosity and conductivity of the spinning solutions decreased, resulting in thinner fibers. Using FTIR and XRD methods, it was shown that if the PVP content was lower than 50 wt %, the VDF–TeFE copolymer adopted a flat zigzag conformation (TTT conformation) and crystalline phases with ferroelectric properties were formed. Gas chromatography results indicated that an increase in the PVP concentration led to a higher residual amount of DMF in the material, causing cytotoxic effects on 3T3L1 fibroblasts. In vivo studies demonstrated that compared to classical gauze dressings impregnated with a solution of an antibacterial agent, ferroelectric composite membranes with 15 wt % PVP provided better conditions for the healing of purulent wounds.
Herein, we report results of the study of the composite ferroelectric scaffolds based on vinylidene fluoride-tetrafluoroethylene copolymer (VDF-TeFE) and polyvinylpyrrolidone (PVP) produced by electrospinning and their application as a wound-healing material. The physicochemical properties of ferroelectric composite polymer scaffolds depending on the content of PVP (in the range from 0 to 50 wt %) including morphology, composition and crystalline structure were studied. The cytotoxicity of materials and the proliferative activity of cells during their cultivation on the surface of formed scaffolds are reported. It has been found that the optimal PVP content in the VDF-TeFE composite scaffolds is 15 wt%. On a model of a full-thickness contaminated wound in vivo, it was shown that piezoelectric scaffolds based on VDF-TeFE copolymer containing 15 wt% PVP provide better wound healing results in comparison with standard gauze dressings impregnated with a solution of an antibacterial agent.
Engineering of colloidal particles and capsules despite substantial progress is still facing a number of unsolved issues including low loading capacity, non-uniform size and shape of carriers, tailoring different functionalities and versatility to encapsulated cargo. In this work, we propose a method for defined-shaped functionally asymmetric polym...
A number of preclinical and clinical studies have demonstrated the efficiency of mesenchymal stromal cells to serve as an excellent base for a cell-mediated drug delivery system. Cell-based targeted drug delivery has received much attention as a system to facilitate the uptake a nd transfer of active substances to specific organs and tissues with h...
Expandable metallic stent placement is often the only way to treat airway obstructions. Such treatment with an uncoated stent causes granulation proliferation and subsequent restenosis, resulting in the procedure’s adverse complications. Systemic administration of steroids drugs in high dosages slows down granulation tissue overgrowth but leads to...
Currently, electrospun synthetic bioresorbable polymer scaffolds are applied in regenerative medicine and tissue engineering as targeted drug delivery devices because of their mechanical and physico-chemical properties. To control the rate of polymer degradation and drug release from polymer scaffolds, surface modification techniques are widely use...
Microcapsules of customized shapes offer significant advantages over spherical ones, including enhanced internalization by host cells, improved flow characteristics, and higher packing capacity. In our work, we propose a method for defined-shape polymer capsules fabrication inspired by a traditional “pelmeni” (dumplings) making process. The propose...
This work describes the preparation and characterization of printed biodegradable polymer (polylactic acid) capsules made in two different shapes: pyramid and rectangular capsules about 1 and 11 μm in size. Obtained core-shell capsules are described in terms of their morphology, loading efficiency, cargo release profile, cell cytotoxicity, and cell...
Wound healing is a complex process and an ongoing challenge for modern medicine. Herein, we present the results of study of structure and properties of ferroelectric composite polymer membranes for wound healing. Membranes were fabricated by electrospinning from a solution of vinylidene fluoride/tetrafluoroethylene copolymer (VDF–TeFE) and polyviny...
Herein, we report results of the study of the composite ferroelectric scaffolds based on vinylidene fluoride-tetrafluoroethylene copolymer (VDF-TeFE) and polyvinylpyrrolidone (PVP) produced by electrospinning and their application as a wound-healing material. The physicochemical properties of ferroelectric composite polymer scaffolds depending on t...
Non-destructive, controllable, remote light-induced release inside cells enables studying of time- and space-specific surface-mediated delivery of bioactive compounds, which is an important approach in a wide range of biomedical tasks, especially those related to the control of cell growth, regenerative medicine, and self-disinfecting structures su...
The clinical need for vascular grafts is associated with cardiovascular diseases frequently leading to fatal outcomes. Artificial vessels based on bioresorbable polymers can replace the damaged vascular tissue or create a bypass path for blood flow while stimulating regeneration of a blood vessel in situ. However, the problem of proper conditions f...
Direct current (DC) reactive magnetron sputtering is as an efficient method for enhancing the biocompatibility of poly (ε-caprolactone) (PCL) scaffolds. However, PCL chemical bonding state, the composition of the deposited coating and their interaction with immune cells remains unknown. Herein, we demonstrated that DC reactive magnetron sputtering...
The clinical need for vascular grafts is associated with cardiovascular diseases frequently leading to fatal outcomes. Artificial vessels based on bioresorbable polymers can replace the damaged vascular tissue or create a bypass path for blood flow while stimulating regeneration of a blood vessel in situ. However, the problem of proper conditions f...
Mitogen-activated protein kinases (MAPKs), including c-Jun N-terminal kinase (JNK), play important role in the regulation of pro-inflammatory cytokine secretion and signaling cascades. Therefore, JNKs are key targets for the treatment of cytokine/JNK-driven diseases. Herein, we developed electrospray poly(lactic-co-glycolic acid) (PLGA) micropartic...
The electrospray method was used for the first time to prepare polymeric capsules from bioresorbable dl-lactide and glycolide copolymer loaded with biological molecules from the cell secretome and, in particular , human interferon-α-2b (IFNα-2b). The obtained nearly spherical submicron capsules were studied by scanning electron and confocal laser m...
The electrospray method was used for the first time to prepare polymeric capsules from bioresorbable dl-lactide and glycolide copolymer loaded with biological molecules from the cell secretome and, in particular, human interferon a-2b (IFN a-2b). The obtained nearly spherical submicron capsules were studied by scanning electron and confocal laser m...
Nitrogen-doped thin titanium dioxide films formed by the reactive magnetron sputtering method on the surface of PLLA electrospun microfibers scaffold were investigated. It was shown that the chemical composition of the films is shifting from titanium dioxide (TiO2) composites saturated with C–NH, C=N, N–C=N and HN–C=O compounds to solid solutions o...
The combination of an efficient encapsulation method of small water-soluble substances with a stimuli-responsive release of defined quantity remains a challenging task. A novel drug delivery system (DDS) representing a free-standing PLLA microchamber arrays film and its application as the cover for implantable endovascular stent are reported in thi...
Synthetic biodegradable polymers are considered to be a highly suitable materials for the targeted drug delivery devices creating. Especially promising is the use of the electrospinning technique, which makes it possible to obtain materials with a high surface-to-volume ratio that provides active diffusion of the drug into the body tissues. In orde...
Polystyrene (PS) is currently mainly used as a sacrificial template during pattern release upon microcontact printing or for self-assembled flat free-standing films. We hereby present a method for creating 3D microstructured free-standing self-assembled polyelectrolyte multilayer (PEM) thin films. The approach presented utilizes a sacrificial micro...
Biodegradable polymer scaffolds for tissue engineering is a promising tec
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