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Mesothelioma and Non Asbestos Exposure
Mesothelioma most commonly develops in the lung's lining (pleura) and abdomen (peritoneum). The rare cancer can also form in the lining of the heart (pericardium) or the testes.
Asbestos exposure is the main risk factor for mesothelioma. Certain mesothelioma patients have no previous history of asbestos exposure.
Exposure to Asbestos
Asbestos is a naturally occurring mineral that was previously employed in industrial and construction products all over the world. People who worked in asbestos industries handled the mineral every day which put them at risk of exposure. Asbestos fibers can get stuck in the lungs which can cause lung disease. This is called asbestosis. As time passes, these trapped fibers can cause mesothelioma. Asbestos fibers can be inhaled, eaten or absorbed through the skin. The risk of developing mesothelioma or other asbestos-related diseases rises when exposed.
The majority of mesothelioma cases stem from exposure to occupational toxins. Asbestos is used in many jobs, including electrical work, and maintenance of automobiles. Because these professions are mostly dominated by males, 75-80% percent of mesothelioma cases are diagnosed in males. However, the gradual elimination of asbestos in the United States and other first-world countries has led to a decrease in exposure on the job. This has led to a shift of cases as asbestos exposure outside of the workplace increasing in frequency.
Non-occupational mesothelioma can occur when asbestos is released from a work environment or is found in the home or school surroundings. The secondhand exposure can also trigger it, such as when a family member touches the clothes worn by an asbestos worker. Those who experience this type of exposure may have symptoms such as breathing problems or chest pain that is often mistaken as heart or lung conditions.
Some studies have linked mesothelioma to non-occupational exposures, but the results vary. A majority of these studies were conducted with a small sample size, and the between-study the degree of heterogeneity is high. Further research is needed to establish the connection between exposure to non-occupational sources and mesothelioma.
People who have been exposed to non-occupational asbestos should discuss their asbestos background with their doctor. If they are concerned, they should seek for a mesothelioma test and a referral to an expert. Specialists in mesothelioma can provide the best treatment and care to improve the patient's outlook. They will review medical records and perform imaging tests to identify mesothelioma. They will also give guidance on how to file mesothelioma suits to claim compensation from asbestos trust fund.
Secondhand Exposure
Although asbestos exposure is the main cause of mesothelioma, it's not the only factor that can cause you to get this cancer. In fact, there is only a tiny amount of evidence that shows that people can develop mesothelioma despite not having directly handled asbestos or employed in an industry that has asbestos-related activities. This is called secondary or non-occupational exposure.
Asbestos fibres are very small and are able to stick to clothing, hair and skin. As a result, workers could bring the hazardous fibers home on their work clothes, and then transfer them to family members. These stray asbestos fibers can be swallowed or inhaled which can lead to mesothelioma.
This type of mesothelioma occurs more frequently in women and is usually found in the lung. It can also affect the chest wall or abdomen. The most commonly reported symptom is shortness of breath (dyspnea) and it may be accompanied by other symptoms like fluid in the lungs, or a swelling in the scrotum.
The mesothelioma that occurs in the lungs is referred to as mesothelioma of the pleural region. Peritoneal mesothelioma is the name for mesothelioma that affects the stomach wall or chest wall. This type of mesothelioma can cause a number of symptoms including abdominal pain, difficulty in breathing and constipation.
According to a variety of studies, individuals who have not been exposed to asbestos in the workplace may still develop mesothelioma due to exposure from secondhand sources. Most often, these people have lived with someone who was exposed to the harmful material. They may have touched the garments of the worker, or they might have had other contact with asbestos.
Veterans are at high risk of developing mesothelioma as a result of the widespread use of asbestos in military bases, ships and other vehicles. The Navy is particularly at risk because asbestos was used to protect the hull of the ship as well as to protect gun turrets. Asbestos was also brought home by sailors from their work on ships that were infected with asbestos.
Environmental Exposure
Mesothelioma has been linked with a variety of substances. The disease is still most often associated with asbestos exposure. Asbestos is a mineral that occurs naturally that was used for a variety of years in manufacturing. The mineral is heat resistant and durable, making it ideal for use in insulation, brakes, shingles flooring, and many other products. When asbestos is broken it produces dust that can be breathed in or swallowed. These fibers can remain in the stomach or lungs for a long time, triggering mesothelioma-related symptoms.
The most frequently reported mesothelioma symptoms are difficulty breathing, chest pain and abdominal discomfort. Asbestos sufferers might be suffering from these symptoms for up to 60 years or longer after their initial exposure. The symptoms can be misinterpreted as other diseases, therefore it is essential to consult your doctor if you exhibit these symptoms. Notifying your doctor of asbestos exposure is essential. This can help avoid a false diagnosis and ensure that you receive the correct treatment.
Mesothelioma that is caused by exposure to asbestos is more prevalent in people who work directly with the substance, but it can also be a problem for loved ones of those exposed. This is known as secondary exposure. Family members could take in asbestos fibers that are present in a worker's shoes, clothing or even tools. They could also be exposed to the particles on their clothing or hair. This is why mesothelioma patients and their families must take care to clean their clothes properly after working with asbestos.
There is oakland asbestos attorney of studies that show a relationship between nonasbestos exposure and mesothelioma. However there aren't any definitive conclusions yet about the role of other agents. For instance, there is some evidence that the zeolites erionite and chrysotile can cause mesothelioma. Erionite is found in soil and rocks in certain regions of Turkey, where mesothelioma incidences are high in pleural mesot.
Research into the relationship between mesothelioma and exposure to nonasbestos continues. Funnel plots have revealed the potential for bias in publications, and the there is a high degree of heterogeneity between studies. However, it's evident that asbestos exposure in the workplace is the most significant risk factor for mesothelioma.
Genetics
Mesothelioma is an uncommon disease caused by malignant mesothelial cells which grow out of control and invade surrounding tissues. It can also spread throughout the body through the blood or lymphatic system, which can affect other organs. Asbestos is the main cause, but it's not the sole cause. The condition could also be triggered by other genetic and environmental factors.
In some instances mesothelioma is seen in people who were not exposed to asbestos. These people are known as non-occupational mesothelioma sufferers. These individuals typically had indirect exposure through the handling of contaminated clothes or home items by an asbestos-exposed individual in their household. It is possible to be diagnosed with mesothelioma after inhaling asbestos fibers from the clothing of a family member. Studies show that these types of mesothelioma cases tend to have longer periods of latency and are more likely to be diagnosed in wives than husbands.
Scientists are investigating the possibility that genetic predispositions to mesothelioma could play a role in its development. Recent studies have revealed that the mutation of BAP1, a gene, increases the risk of mesothelioma developing in those who are exposed to asbestos. This is a significant finding, as it could be the basis for improved screening procedures for those at risk of developing mesothelioma.
Researchers have discovered a number genes that are linked to mesothelioma. These genes are usually mutated in mesothelioma and suppress tumor growth. These genes include the massive homolog 2 of tumor suppressor (LATS2) and the NF2.
People with mesothelioma in their family are at a higher risk of developing the mesothelioma. Some genes, such as the BAP1 that are passed down from parents. Veterans have the highest rates of mesothelioma in comparison to other occupational groups because asbestos was extensively used in the military. Those who served on ships or in the Navy were at highest risk of developing asbestos-related cancer due to exposure in the construction of ships, insulation and fireproofing materials.