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Criteria for Initial Approval Aetna consider testosterone cypionate injection (Depo-Testosterone or generic formulation) medically necessary for the following indications: Primary hypogonadism or hypogonadotropic hypogonadism when both of the following criteria are met:1. Primary hypogonadism (. Read more Did you find an answer to your question? Yes No DOSAGE AND ADMINISTRATION Prior to initiating DEPO-Testosterone (testosterone cypionate), confirm the diagnosis of hypogonadism by ensuring that serum testosterone concentrations have been measured in the morning on at least. Read morePrior to initiating DEPO-TESTOSTERONE (testosterone cypionate injection), the diagnosis of hypogonadism should be confirmed by ensuring that serum testosterone concentrations have been measured in the morning on at least two separate days and that these serum testosterone concentrations are below the normal range. . Administration. Parenteral . How To Take Testosterone Cypionate Testosterone cypionate is available as an injectable solution. You can take it either as an intramuscular shot or as a subcutaneous injection. Dosages. Typical drug regimes are between 50 mg ml and 400 mg ml every two weeks. The maximum recommended dose is 400 mg ml as an intramuscular injection every two weeks. Dosage and Administration How Supplied/Storage and Handling Testosterone Cypionate Description Testosterone cypionate, for intramuscular injection, contains testosterone cypionate which is the oil-soluble 17 (beta)-cyclopentylpropionate ester of the androgenic hormone testosterone. Testosterone Cypionate Injection is indicated for replacement therapy in the male in conditions associated with symptoms of deficiency or absence of endogenous testosterone. . Dosage and Administration. DOSAGE AND ADMINISTRATION. Prior to initiating Testosterone Cypionate Injection, confirm the diagnosis of hypogonadism by ensuring that serum . Context: Injections with intramuscular (IM) testosterone esters have been available for almost 8 decades and not only result in predictable serum testosterone levels but are also the most inexpensive modality. However, they are difficult to self-administer and associated with some discomfort. Recently, subcutaneous (SC) administration of testosterone esters has gained popularity, as self . Testosterone injections such as testosterone cypionate and testosterone enanthate can easily be administered from one's own home. The most important factor is determining which of the testosterone injection sites will best suit your needs. Step 1: Setting up for the injection Find a comfortable, well-lit working place and inject at the same time each day. Adapted from immunize. org/catg. d/p3084. pdf on 3/16/2013. We thank the Immunization Action Coalition. Clean your work area. Remove medication from the refrigerator and let it reach room temperature. Currently, testosterone therapy is indicated for men with unequivocal, organic, or pathologic androgen deficiency to alleviate symptoms and maintain secondary sexual characteristics by raising testosterone into the normal male range ( 1 ). Descriptions Testosterone injection is used for the treatment of men whose bodies do not make enough natural testosterone, a condition called hypogonadism. Testosterone is a male hormone responsible for the growth and development of the male sex organs and maintenance of secondary sex characteristics. Find patient medical information for testosterone cypionate intramuscular on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Misusing testosterone cypionate (Depo-Testosterone) can cause serious problems involving the heart and mental health, such as heart attack, heart failure, stroke, liver problems, depression, delusions, hallucinations, and aggression. Continued misuse of testosterone cypionate (Depo-Testosterone) can lead to addiction. Testosterone cypionate: 50-400 mg IM every 2-4 weeks; Testosterone enanthate (generic): 50-400 mg IM every 2-4 weeks . of anaphylaxis reported during or immediately after administration; may occur after first dose; Observe patients for 30 minutes in healthcare setting to provide immediate medical treatment in event of serious POME reactions . Testosterone cypionate: 20-25°C. Protect from light. Testosterone enanthate: Room temperature. Testosterone undecanoate: 25°C (may be exposed to 15-30°C). A precipitate may form if testosterone cypionate or testosterone enanthate injection is stored at low temperatures; the precipitate will dissolve after shaking and warming to room . The chemical name for testosterone cypionate is androst-4-en-3-one, 17- (3-cyclopentyl-1-oxopropoxy)-, (17β)-. Its molecular formula is C 27 H 40 O 3, and the molecular weight 412. 61. DEPO-Testosterone Injection is available in two strengths, 100 mg/mL and 200 mg/mL testosterone cypionate. 10. 1210/jc. 2017-00359 Testosterone (T) is commonly administered intramuscularly to treat hypogonadal males and female-to-male (FTM) transgender patients. However, these injections can involve significant discomfort and may require arrangements for administration by others. Brand name: Depo-testosterone. Testosterone cypionate comes only in the form of an injectable solution given into your muscle. You can give this medication to yourself at home after your doctor. Testosterone Cypionate Injection, USP for intramuscular injection, contains Testosterone Cypionate, USP which is the oil-soluble 17 (beta)- cyclopentylpropionate ester of the androgenic hormone . CLINICAL PHARMACOLOGYDOSAGE AND ADMINISTRATION Prior to initiating Testosterone Cypionate Injection, confirm the diagnosis of hypogonadism by ensuring that serum testosterone concentrations have been measured in the morning on at least two separate days and that these serum testosterone concentrations are below the normal range. Testosterone Enanthate and Cypionate: 50 to 400 mg IM injection every 2 to 4 weeks IMPLANT: 2 to 6 pellets (75 mg each) implanted subcutaneously every 3 to 6 months. The number of pellets to be implanted depends upon the minimal daily requirements of testosterone propionate administered parenterally. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. During exogenous administration of androgens, endogenous testosterone release is inhibited through feedback inhibition of pituitary luteinizing hormone (LH). . thus, testosterone cypionate can be given at intervals of two to four weeks. Testosterone in plasma is 98 percent bound to a specific testosterone-estradiol binding globulin, and about .
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