Ten Things You Need To Know About Advanced Depression Treatment
Advanced Depression Treatment
If you don't experience any improvement from the first-line antidepressant, your doctor might increase the dose or add another type of medication. They might also suggest psychotherapy.
Modern psychotherapy techniques like augmented depression therapy have empirical evidence-based support and can help reduce depression symptoms. These therapies are focused on the identification and resolution of specific ways that depression affects your daily life.
Transcranial Magnetic Stimulation (TMS)
TMS is a non-invasive brain stimulation technique that utilizes magnetic pulses to influence the brain's neurons that control mood. It is often prescribed to treat depression when medication fails or isn't appropriate for the individual. It is used to treat PTSD and, in some cases, combined psychotherapy. TMS is a safe and safe treatment that has no significant side adverse effects.
During the session, a healthcare professional will install an electromagnetic coil over the area of your brain that regulates mood. In the case rTMS this is called the dorsolateral frontal cortex (dLPFC). It is a tiny area that is located in front of your head. You will hear a click sound and feel a tapping sensation as the device delivers signals to your brain. The healthcare professional will adjust the settings to stimulate the specific areas of your brain.
The healthcare professional will determine the intensity of the pulses using the amount of energy required to induce the thumb to twitch. This is crucial, since it lets them know the power they're using to ensure patient safety. In the past, pulses were administered at 120% of the motor threshold. But, current research is focusing on speeding up TMS treatment to decrease the duration of treatment and increase the rate of response.
In a controlled, randomized study researchers have demonstrated that TMS can help people with major depressive disorder (MDD) who are unable to respond to antidepressants. The study found that patients who were treated with rTMS experienced significant improvements in symptoms such as depression and sadness, as well as changes in appetite, and loss of enjoyment or enthusiasm for activities. The study also showed improvements that lasted a long duration.
Contrary to other forms of brain stimulation, like vagus nerve stimulation and electroconvulsive therapy, TMS does not interfere with psychotherapy. It is also safe for pregnant women and has a low risk of seizures. However, some people can experience pain or discomfort on their scalp under the magnet while they are receiving treatment.
TMS treatments usually last around 30 minutes. The provider will inform you the length of time the treatment will be and may pause the pulses at this point to allow the magnet to cool down.
Vagus Nerve Stimulation (VNS)
VNS (also known as Vagus Nerve Stimulation) is an approach that utilizes timing of electrical signals to alter brainwave patterns and lessen depression symptoms. It's a surgically implanted device that utilizes a small pulse generator that connects to a wire which is placed beneath the skin and wound around the left vagus nerve in the neck. The procedure is FDA-approved for treating depression that is resistant to treatment in patients who have not received relief from other treatments such as psychotherapy or medication. It is also approved for seizure control in certain epileptic patients.
In the largest clinical study of VNS researchers compared the effectiveness with a sham device in people who had treatment-resistant unipolar or depressed-phase bipolar disorder. The VNS group was given a low dose, medium dose or high dose of electrical stimulation over a 22-week period. The primary goal was a change in Inventory of Depressive Symptomatology Self Report (IDS-SR30) score throughout the study. Patients in the VNS group had significantly better results than those in the group with a sham. After a 12-month follow-up participants in the VNS group had a mean IDS-SR30 score of 9.3 points, whereas those in the group with a sham score had a score of 4.2 points.
The VNS treatment was well-tolerated. The most frequent side effects were voice distortion hoarseness, a feeling of numbness, and a feeling on the chest. Other reported side effects included headache, tingling, fatigue and changes in speech or swallowing. Some of these side effects were observed more frequently in higher dose groups whereas others occurred at all doses. The frequency of AEs in this study was similar to previous studies and generally cleared by the end the acute study period.
Psychiatrists from Ohio State Wexner Medical Center are frequently invited to participate in national discussions on the best way to treat depression and mood disorders. Our experts are helping define national standards for health treatment. We are also the site for an international clinical trial, called RECOVER which is being conducted by the Centers for Medicare & Medicaid Services. The purpose of this study is to examine VNS for treatment-resistant depression. This is a crucial research effort, as the evidence available today suggests that VNS can offer improving benefit and hope to this difficult-to-treat chronic population.
Electroconvulsive Therapy (ECT)
ECT is a highly effective advanced depression treatment for those who aren't getting better with medications. It is particularly beneficial for those who are suicidal or unable to wait for their medication to start working.
During the ECT procedure doctors send tiny electric currents to the brain to intentionally cause an immediate seizure. This appears to alter brain chemical processes, and may help alleviate symptoms of a variety of mental health issues. ECT has been used since the 1930s and despite the stigma associated with the treatment, a lot of people have seen positive results from it.

Your psychiatrist will first need to perform a thorough psychiatric evaluation before recommending ECT. They will then review your medical records and perform several tests, such as an electrocardiogram, blood tests, and maybe an X-ray of your chest. They will also ask you what you think about the possibility of having ECT and take into consideration any opinions from family members, friends or other advocates who are either supporting or speaking on your behalf.
The ECT treatment is given while you sleep under general anesthesia, so you won't feel anything during the procedure. A mouth guard is placed to protect your teeth and an air mask is placed over your face to allow oxygen. An anesthesiologist injects an anesthetic through a needle in your vein. After you fall asleep, electrodes will be placed on either one side or both sides of your head depending on whether you're receiving unilateral or bilateral ECT. These pulses deliver small electrical impulses to the brain, which triggers a short seizure. It lasts for 20 to 60 seconds and you'll wake up shortly after it's over.
innovative depression treatment www.iampsychiatry.com can withdraw your consent to ECT at any time before the initial treatment. This is your right under the Care Quality Commission (CQC) regulations and your doctor must always take into account your wishes when deciding on ECT for you.
Some people find that ECT is a viable alternative after having tried other treatments and haven't seen any improvement. However, it can also be used to treat mild depression or severe psychosis, or when you pose at risk to others or yourself and can't wait for medication to take effect. Most people will need to attend several ECT sessions spread over three to six weeks.
Light therapy
Light therapy compensates the lack of sunlight. This is a factor that could contribute to seasonal affective disorder (formerly known as major depression). It is used as a stand-alone treatment or as an addition to other treatments, such as psychotherapy or medication. When you undergo light therapy you are seated next to a light box that emits white light that is bright and bright. The light usually has between 10,000 and 2,500 in lux. During each treatment session you will sit for around 30 minutes in front of the light. The light can help improve your mood and ease symptoms of SAD like feeling constantly tired and sleeping excessively.
Although scientists don't know for certain how light therapy works to treat SAD however, they do know that it has a direct influence on the circadian rhythms. Circadian rhythms are biological cycles that influence sleep patterns hormone levels, sleep patterns, and other vital functions. Light therapy can alter the internal clock of your body by influencing the release of melatonin, the chemical that regulates sleep and wake cycles. It also impacts neurotransmitter functions by altering the production of serotonin a chemical that lifts your mood.
Numerous studies have demonstrated how light therapy can help improve depression symptoms and boost the effectiveness of antidepressant medication. In addition, some studies have demonstrated that light therapy is effective in treating bipolar disorder. These findings are encouraging and suggest light therapy might be a possibility for people with both depression and bipolar disorder.
Before you begin using light therapy, speak to your physician or a mental health professional about it. They can help you choose the right device for your needs and provide guidance on how to utilize it. They can also tell whether it interferes with other medications you are taking.
Light therapy is a safe treatment that doesn't cause any serious side adverse effects. However, you should use it according to the instructions of your doctor. It is essential to seek treatment as soon as you can if you're suffering from severe depression. Depression is a serious condition, and it can have serious consequences for your emotional and physical well-being. In extreme cases, depression may cause suicidal thoughts. If you are having suicidal thoughts, seek assistance immediately from a mental health professional.