Temgesic Uses

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A derivative of the opioid alkaloid thebaine that is a more potent and longer lasting analgesic than morphine. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use. Temgesic is a synthetic opioid analgesic and thebaine derivative, with a longer duration of action than morphine. Temgesic interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, buprenorphine exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Temgesic depresses the respiratory centers, depresses the cough reflex, and constricts the pupils. Your doctor has ordered buprenorphine, a strong analgesic painkiller , to relieve your pain. The drug will be added to an intravenous fluid that will drip through a needle or catheter placed in your vein. You will probably receive sufentanil continuously for around-the-clock pain relief. Your doctor also may order other pain medications to make you feel more comfortable. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Your health care provider doctor, nurse, or pharmacist may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how you respond to the medication. Buprenorphine is metabolized to norbuprenorphine by cytochrome CYP 3A4. Based on anecdotal reports, there may be an interaction between buprenorphine and benzodiazepines. There have been a number of reports in the post-marketing experience of coma and death associated with the concomitant intravenous misuse of buprenorphine and benzodiazepines by addicts. For the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence. Temgesic is also a kappa-opioid receptor antagonist. The partial agonist activity means that opioid receptor antagonists e. The binding to the mu and kappa receptors results in hyperpolarization and reduced neuronal excitability. Not Available Food Interactions: Not Available Generic Name: Buprenex; Subutex; Temgesic; Absorption: Manifestations of acute overdose include pinpoint pupils, sedation, hypotension, respiratory depression and death. Buprenorphine undergoes both N-dealkylation to norbuprenorphine and glucuronidation. The N-dealkylation pathway is mediated by cytochrome P 3A4 isozyme. Norbuprenorphine, an active metabolite, can further undergo glucuronidation. Not Available Chemical Formula: Humans and other mammals. Navigation Navigation Search Geo Rus. Contact Location map Moscow St. Medication Nerve blocks and trigger point injection Physiotherapy Reflexotherapy acupuncture Spinal traction Medical exercise therapy, occupational therapy Yoga Massage therapy Chiropractic, osteopathy Visceral manipulation. Temgesic — general information Pharmacology of Temgesic Temgesic for patients Temgesic interactions Temgesic contraindications Additional information about Temgesic. Temgesic - General Information A derivative of the opioid alkaloid thebaine that is a more potent and longer lasting analgesic than morphine. Temgesic for patients Your doctor has ordered buprenorphine, a strong analgesic painkiller , to relieve your pain. Additional information about Temgesic Temgesic Indication:

Temgesic Uses

Temgesic Uses

buprenorphine

Temgesic 200 microgram Sublingual tablets

What is temgesic used for

Temgesic Uses

buprenorphine

buprenorphine

What is temgesic used for

Temgesic Uses

buprenorphine

Temgesic Uses

Temgesic Uses

Temgesic Uses

Temgesic Uses

Temgesic Uses

What is temgesic used for

What is temgesic used for

Temgesic Uses

buprenorphine

buprenorphine

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