Taboo 17 And 18 1997

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Subject: 1 selected item: 9175983 - PubMed
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1 Department of Surgical Gastroenterology, Hvidovre University Hospital, Denmark.
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1 Department of Surgical Gastroenterology, Hvidovre University Hospital, Denmark.
Major surgery is still associated with undesirable sequelae such as pain, cardiopulmonary, infective and thromboembolic complications, cerebral dysfunction, nausea and gastrointestinal paralysis, fatigue and prolonged convalescence. The key pathogenic factor in postoperative morbidity, excluding failures of surgical and anaesthetic technique, is the surgical stress response with subsequent increased demands on organ function. These changes in organ function are thought to be mediated by trauma-induced endocrine metabolic changes and activation of several biological cascade systems (cytokines, complement, arachidonic acid metabolites, nitric oxide, free oxygen radicals, etc). To understand postoperative morbidity it is therefore necessary to understand the pathophysiological role of the various components of the surgical stress response and to determine if modification of such responses may improve surgical outcome. While no single technique or drug regimen has been shown to eliminate postoperative morbidity and mortality, multimodal interventions may lead to a major reduction in the undesirable sequelae of surgical injury with improved recovery and reduction in postoperative morbidity and overall costs.
Kehlet H. Kehlet H. Can J Surg. 1991 Dec;34(6):565-7. Can J Surg. 1991. PMID: 1747833 Review.
Kehlet H, Moesgaard F. Kehlet H, et al. Scand J Gastroenterol Suppl. 1996;216:218-24. doi: 10.3109/00365529609094576. Scand J Gastroenterol Suppl. 1996. PMID: 8726294 Review.
Kehlet H, Dahl JB. Kehlet H, et al. Lancet. 2003 Dec 6;362(9399):1921-8. doi: 10.1016/S0140-6736(03)14966-5. Lancet. 2003. PMID: 14667752 Review.
Rosenberg J, Kehlet H. Rosenberg J, et al. Ugeskr Laeger. 2001 Feb 12;163(7):908-12. Ugeskr Laeger. 2001. PMID: 11228785 Review. Danish.
Holte K, Kehlet H. Holte K, et al. Minerva Anestesiol. 2002 Apr;68(4):152-6. Minerva Anestesiol. 2002. PMID: 12024073 Review.
de Carvalho Almeida RF, Serra HO, de Oliveira LP. de Carvalho Almeida RF, et al. J Orthop Surg Res. 2021 Aug 12;16(1):488. doi: 10.1186/s13018-021-02640-x. J Orthop Surg Res. 2021. PMID: 34384468 Free PMC article.
Montagne F, Guisier F, Venissac N, Baste JM. Montagne F, et al. Cancers (Basel). 2021 Jul 23;13(15):3711. doi: 10.3390/cancers13153711. Cancers (Basel). 2021. PMID: 34359612 Free PMC article. Review.
Peerbocus M, Wang ZJ. Peerbocus M, et al. Res Rep Urol. 2021 Jul 29;13:535-547. doi: 10.2147/RRU.S307385. eCollection 2021. Res Rep Urol. 2021. PMID: 34350137 Free PMC article. Review.
Zieglowski L, Kümmecke AM, Ernst L, Palme R, Weiskirchen R, Talbot SR, Tolba RH. Zieglowski L, et al. PLoS One. 2021 Aug 2;16(8):e0255175. doi: 10.1371/journal.pone.0255175. eCollection 2021. PLoS One. 2021. PMID: 34339407 Free PMC article.
Zhu W, Yan Y, Sun Y, Fan Z, Fang N, Zhang Y, Yin M, Wan H, Mo W, Lu W, Wu X. Zhu W, et al. J Orthop Surg Res. 2021 Jul 28;16(1):469. doi: 10.1186/s13018-021-02599-9. J Orthop Surg Res. 2021. PMID: 34315507 Free PMC article.


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Taboo 17 And 18 1997