Sperm abnormality smoking
Sperm abnormality smoking
Abstract Previous studies have found that smoking is associated with decreased male fertility via altering the quality of semen. However, the mechanism by which cigarette smoking affects semen quality remains to be fully elucidated. Heavy smoking-induced DNA damage has been reported to correlate with abnormal spermatozoa and male infertility. It has been reported that, in response to DNA ...
2 days ago
Jul 15, 2025
Mar 4, 2024
The use of tobacco is widespread among men and poses a significant concern for reproductive health. This review synthesizes recent evidence on the impact of cigarette smoking on spermatogenesis, emphasizing its effects on semen quality, reproductive hormone levels, metabolic profile, and sperm DNA fragmentation, which contribute to infertility.
igarette smoking was associated with reduced sperm count, motility, and morphology. Therefore, the final suggestion was that cigarette smoking has an overall negative impact on semen parameters [26]. The explanation of abnormalities in sem
The effect of tobacco smoking on sperm were more significant in smokers than in non-smokers. Alcohol consumption affects the quality and quantity of semen. Both tobacco smoking and alcohol consumption combined may amplify their negative effects toward semen parameters.
5 days ago
The effects of smoking on human health have long been documented. However, only a few studies have highlighted the di-rect effects of nicotine on sperm function. Nicotine, as a chemical compound found in tobacco, has been shown to modulate different aspects of spermatogenesis and sperm functions.
Moreover, negative associations between seminal lead and cadmium concentrations and sperm concentration, motility, and morphological abnormalities in abnormal spermatozoa have been observed [26]. 2. Means of smoking and routes of nicotine exposure Several types of smoke are produced when a cigarette is smoked (Fig. 1).
While poor sperm morphology (shape) itself doesn't directly cause birth defects, poor sperm quality, especially DNA damage, can increase risks for miscarriage,
Apr 14, 2025
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Abnormal shapes can hinder swimming or penetration capability, while low concentration reduces odds simply by numbers. Various environmental factors—like heat exposure, toxins, smoking, alcohol consumption—and medical conditions can negatively affect these parameters. Table: Key Sperm Parameters and Their Impact on Fertilization
Cigarette smoking seems to have a negative impact on men's reproductive health, but our knowledge of its effects on the reproductive function of Russian men is still very limited. The purpose of this study was to evaluate the effect of cigarette ...
Most of the reports showed that smoking reduces sperm production, sperm motility, sperm normal forms and sperm fertilising capacity through increased seminal oxidative stress and DNA damage. Few papers reported nonsignificant differences in semen parameters between smokers or non-smokers.
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2 days ago
These compounds can pass the blood-testis barrier, which subsequently causes harm of diverse degree to the germ cells. Although controversial, smoking has been shown to cause not only a decrease in sperm motility, sperm concentration, and an increase in abnormal sperm morphology, but also genetic and epigenetic aberrations in spermatozoa.
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The contradictions in studies on the consequences of heavy tobacco smoking and alcohol consumption on male fertility encouraged us to explore the correlations between smoking, alcohol intake, and sperm quality, including its DNA, in male patients experiencing fertility problems, and to determine which habit causes more damage to sperm quality.
Male smokers can suffer decreased sperm quality with lower counts (numbers of sperm) and motility (sperm's ability to move) and increased numbers of abnormally-shaped sperm. Smoking might also decrease the sperm's ability to fertilize eggs. Women who smoke do not conceive as efficiently as nonsmokers.
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Evidence suggests that among male-related risk factors leading to infertility, smoking plays a significant contribution. With the exception of few controversial studies, the negative impact of smoking on semen quality including sperm count, motility, and morphology is well documented [2-4].
Background: This study aimed to estimate stress markers, oxidative stress (OS), reproductive hormones and sperm parameters in male smokers and non-smokers and observe the impact of oxidative stress markers and smoking on sperm count, motility and morphology in a selected population of Karachi ...
Smoking and BMI did not statistically affect the semen parameters in the correlation test. Semen volume, sperm count, motility, viability, and morphology of all the subjects did not correlate with the smoking history or BMI. Table 2 shows the results of the analyses for the semen abnormality risk factors.
Dec 13, 2025
Learn about abnormal sperm and its impact on male fertility. Know the various types, causes, with sperm abnormalities, and treatment options to improve sperm health.
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This study was conducted to find the relative risk of semen abnormality with respect to smoking history and obesity.Subfertile or infertile men were enrolled in this study from July 2010 to June 2011. All participants provided their cigarette use information, ...
Our results show that cigarette smokers have a higher frequency of morphologically abnormal sperm than non- smokers, but from the data available we cannot relate the degree of abnormality to the number of cigarettes smoked.
Conclusion (s): Cigarette smoking among teenagers was associated with increases in disomic sperm and a diminution in specific aspects of semen quality. Such defects may affect male fertility and may increase future chances of fathering offspring with aneuploidy syndromes.
Jul 23, 2024
Smoking has negative reproductive consequences. This study investigated the effect of smoking cessation on the main semen parameters. We included 90 participants who applied to our infertility clinic and smoked at least 20 cigarettes a day for at ...
Paternal exposure to constituents of cigarette smoke (CS) is reportedly associated with infertility, birth defects and childhood cancers even though the mechanism behind this relationship is still unclear. Chronic cigarette smoking by men leads to ...
This doesn't mean that a father's smoking doesn't affect the health of the child in other ways. Researchers did find an increased risk of birth defects in the children of male smokers, as well as an increased risk of cancer. This may be related to damage to sperm DNA. One study looked at sperm DNA of smokers and non-smokers.
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Smoking can severely impair male fertility. Smoking can directly affect sperm count, sperm shape and sperm motility. Here are 5 points to know
Background: Cigarette smoking seems to have a negative impact on men's reproductive health, but our knowledge of its effects on the reproductive function of ...
Heavy smoking was associated with decreased sperm counts and alcohol consumption was associated with increased numbers of morphologically abnormal sperm.
Learn how smoking and nicotine can affect your reproductive health and pregnancy.
We also analyzed the expression levels of antioxidant enzymes and heat-shock response-related proteins to explore the activation of signaling pathways involved in stress response within sperm cells. Our results revealed that tobacco consumption reduced semen volume and total sperm count.
FAQ Q. Does smoking really affect male fertility? Yes, smoking can significantly impact male fertility. It can lead to reduced sperm count, impaired sperm motility (swimming ability), abnormal sperm shape, and even damage to sperm DNA. These factors collectively make it harder for men to conceive a child. Q. Can quitting smoking improve sperm ...
This study aimed to estimate stress markers, oxidative stress (OS), reproductive hormones and sperm parameters in male smokers and non-smokers and observe the impact of oxidative stress markers and smoking on sperm count, motility and morphology in ...
Sep 11, 2025
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To assess the effect of smoking on sperm vitality, sperm DNA integrity, semen reactive oxygen species, and zinc levels in fertile men.One-hundred sixt…
Jun 30, 2025
Studies have examined the effects of tobacco smoking and alcohol consumption on human seminal quality. 3 - 5 It is likely that smoking adversely affects male reproductive health. 3, 5, 6 Although chronic heavy alcohol consumption has been associated with abnormal sperm morphology, 4, 7 studies regarding the relationship between moderate ...
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To investigate the association between smoking, semen quality, and the histone-to-protamine transition ratio in mature sperm.Biochemical and molecular…
Good news: If you use cannabis and would like to promote sperm health, there are a few things you can do.
These findings suggest that cigarette smoking may have deleterious effects on sperm nuclear quality and that sperm DNA fragmentation can therefore be considered as an independent parameter with diagnostic, prognostic, and strategic value in the treatment of infertility.
The contradictions in studies on the consequences of heavy tobacco smoking and alcohol consumption on male fertility encouraged us to explore the correlations between smoking, alcohol intake, and sperm quality, including its DNA, in male patients experiencing fertility problems, and to determine which habit causes more damage to sperm quality.
A new systematic review and meta-analysis comprising 5865 men shows that cigarette smoking is associated with reduced sperm count and motility. Deterioration of semen quality is more pronounced in moderate and heavy smokers.
Oct 23, 2024
In conclusion, with reference to the clinical endpoints which were studied in this analysis, tobacco smoking was associated with a lower sperm count and an increase in the number of morphological defects of spermatozoa.
Sperm disorders include defects in quality or quantity of sperm produced and defects in sperm emission. Diagnosis is by semen analysis and genetic testing. The most effective treatment is usually in vitro fertilization via intracytoplasmic sperm injection.
We assessed the concomitant impact of cigarette smoking and alcohol consumption in men presenting for primary couple's infertility. Data from 189 infertile men were analyzed. Semen analysis, serum hormones, and sperm DNA fragmentation (SDF) were obtained. ...
A number of reports suggest that nicotine has detrimental effects on sperm quality including sperm DNA integrity, leads to decreased sperm motility, viability, concentration, and abnormalities in the offspring (Fig. 1) [23, 24]. Nicotine can also disrupt hormonal pathways involved in male fertility thus affecting both sperm production and functioning of the male reproductive system as a whole ...
Jan 11, 2024
Tests have shown that sperm exposed to high levels of THC began to swim in an abnormal fashion, and were less able to attach to an egg so that fertilisation could take place.
Numerous studies have attempted to assess the effects of smoking on male reproductive physiology, including sperm parameters, male reproductive anatomy, as well as the male hormonal axes. Yet the results have been equivocal and contradictory. Our objective was to...
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Lewis et al. [170] associated cigarette smoking with decreased sperm count, alterations insperm motility and overall increased number of abnormal spermatozoa. Besides, smoking and consumption of alcohol and caffeine have been associated to the increase in nuclear DNA damage of the white blood cells [171,172].
Men, got fertility issues? Smoking marijuana may affect sperm size and shape, minimizing the likelihood of egg fertilization.
PIP: The possible effects of cigarette smoking on sperm were investigated in a blind study involving 103 smokers and 135 nonsmokers. The quality of sperm from study subjects was assessed on the basis of density (number), motility, and morphologic abnormalities.
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