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Medically reviewed by L. Last updated on Sep 17, Mescaline is a psychedelic hallucinogen obtained from the small, spineless cactus Peyote Lophophora williamsi , the San Pedro cactus, Peruvian torch cactus, and other mescaline-containing cacti. It is also found in certain members of the Fabaceae bean family and is produced synthetically. People have used hallucinogens for hundreds of year, mostly for religious rituals or ceremonies. From the earliest recorded time, peyote has been used by natives in northern Mexico and the southwestern United States as a part of traditional religious rites. Mescaline leads to rich visual hallucinations which were important to the native peyote cults. It has an effect that is similar to LSD or psilocybin magic mushrooms , other hallucinogenic drugs. The top of the cactus above ground, or the crown, consists of disc-shaped buttons that are cut from the roots and dried. These buttons are generally chewed or soaked in water to produce an intoxicating tea. It can be consumed raw or dried but is extremely bitter. The hallucinogen may also be ground into powder for oral capsules, or smoked with marijuana and tobacco. The hallucinogenic dose is about 0. However, different doses can affect people in various ways, and doses extracted from plants can vary widely. Mescaline is used primarily as a recreational drug and is also used to supplement various types of meditation and psychedelic therapy. It is classified as a schedule I drug in the U. Common effects after use may include:. Like most psychedelic hallucinogens, mescaline is not physically addictive; however, it can cause tolerance meaning higher doses are need to achieve the same hallucinogenic effect. Mescaline-containing cacti can induce severe vomiting and nausea, which is an important part to traditional Native-American or Shaman ceremonies and is considered a cleansing ritual and a spiritual aid. If you take prescription medications, there are no well-controlled studies to determine the overall effect of drug interactions. Medications that have an effect in the brain and may affect serotonin levels for example: Drugs that affect the circulatory system, heart , or have stimulant affects may lead to rapid pulse and dangerous outcomes. Other drug interactions are also possible, although scientific data are limited. According to the National Institute of Drug Abuse NIDA , researchers have found that mescaline found in peyote may affect the fetus of a pregnant woman using the drug. There are no FDA-approved medications to treat abuse of mescaline or other hallucinogenic drugs. Research needs to be completed to evaluate the effects of behavioral therapies for these substances. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. By clicking Subscribe, I agree to the Drugs. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices. Subscribe to receive email notifications whenever new articles are published. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. To view content sources and attributions, please refer to our editorial policy. We comply with the HONcode standard for trustworthy health information - verify here. Mescaline Medically reviewed by L. Common or street names: Sources Peyote And Mescaline. Peyote use during pregnancy. Tolsura Tolsura itraconazole is an azole antifungal indicated for the treatment of Dextenza Dextenza dexamethasone ophthalmic insert is a corticosteroid intracanalicular Subscribe to free Drugs.

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