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For full functionality, it is necessary to enable JavaScript. Here are instructions how to enable JavaScript in your web browser. Any data you provide will be primarily stored and processed in the United States, pursuant to the laws of the United States, which may provide lesser privacy protections than European Economic Area countries. Learn more in our Privacy Policy. We use cookies and similar technologies to improve your browsing experience, personalize content and offers, show targeted ads, analyze traffic, and better understand you. We may share your information with third-party partners for marketing purposes. To learn more and make choices about data use, visit our Advertising Policy and Privacy Policy. Log in with your Medical News Today account to create or edit your custom homepage, catch-up on your opinions notifications and set your newsletter preferences. Sign up for a free Medical News Today account to customize your medical and health news experiences. It increases the levels of naturally occurring dopamine and norepinephrine in the brain. The effect lasts longer than with cocaine, it is cheaper, and it is easy to make with commonly available ingredients. Street names for this drug include chalk, crank, ice, crystal, meth, and speed. Discovered in the late 19th century, amphetamine was first used as a nasal decongestant and a respiratory stimulator. During World War 2, methamphetamine — similar in structure to amphetamine — was used to keep military personnel alert and to improve endurance and mood. In time, it became clear that methamphetamine was dangerously addictive. In the s, the drug was added to the schedule II list of controlled substances. Methamphetamine is illegal except when it is prescribed by a physician for a very limited number of medical conditions. Methamphetamine is easy to produce and it is a potent drug, so it remains a serious drug of abuse. Long-term use is associated with devastating effects on the user and society. Methamphetamine is a white, odorless, bitter-tasting crystalline powder that easily dissolves in water or alcohol. Amphetamine is prescribed to treat some medical conditions, including:. Methamphetamine, a drug with a similar substance, is used illegally for its pleasurable effects. Misuse can be hazardous and even deadly. Illegal forms of the drug can be smoked , snorted, injected, or ingested orally. Smoking or injecting methamphetamine causes an immediate, intense 'rush' or bliss that lasts for a few minutes. Snorting does not produce the intense rush, but a euphoric high within 3 to 5 minutes of ingestion. The oral effects can be felt within 20 minutes. People take methamphetamine for its pleasurable effects. The pleasurable effects of methamphetamine happen when the body releases very high levels of the neurotransmitter dopamine. This is the brain chemical involved in motivation, pleasure, and motor function. As with many stimulants, methamphetamine is most often abused in a 'binge and crash' pattern. Users try to maintain the high by taking more of the drug before the first dose wears off. The drug acts on parts of the brain involved in reward, and this makes taking another dose tempting. Some people binge for several days, avoiding food and sleep while continually using the drug until it is finished. However, these high levels of dopamine are also thought to help make the drug more toxic to nerve terminals in the brain. Methamphetamine is different from and more dangerous than other stimulants because a larger percentage of the drug remains unchanged in the body. This allows the drug to be present in the brain longer, extending the stimulant effects. When amphetamine is prescribed legally, doses normally range from 2. Since illegal drugs are not regulated, there is no way to know how much methamphetamine is in each illicit dose. A high body temperature, heart attack , and seizures can occur with overdose. If not treated immediately, an overdose can result in organ failure and death. People use methamphetamine because they enjoy the effects. However, it can have some dangerous side effects. The following symptoms of methamphetamine psychosis are also possible:. Researchers have reported that up to 50 percent of the dopamine-producing cells in the brain can be damaged after prolonged exposure to relatively low levels of methamphetamine. Psychotic symptoms can last for months or years after discontinuing methamphetamine use. They can spontaneously recur. Methamphetamine use can lead to a number of other health problems, including dependence, heart problems, and other physical and mental health issues. The drug has a high potential for abuse and dependence. Tolerance develops quickly, and psychological addiction can develop within a relatively short space of time. Methamphetamine is very addictive. This is because a large amount of dopamine remains in the brain cells synapses for long periods of time after use. The dopamine keeps the cells activated, allowing the user to experience the powerful feelings of euphoria. After a while, the user is unable to produce dopamine naturally and requires the drug to feel normal, needing larger doses to experience feelings of pleasure. Stopping suddenly does not cause a physical withdrawal, as with heroin. Instead, the person may feel extreme fatigue, mental depression , irritability, apathy, and disorientation. Methamphetamine use increases the risk of heart problems, such as chest pain, abnormal heart rhythm, and high blood pressure. This can lead to a heart attack, acute aortic dissection, or sudden cardiac death, even after using the drug for the first time. There is a higher risk of stroke , possibly due to elevated blood pressure or faster rate of atherosclerosis. Methamphetamine abuse can also cause tooth decay so severe that most of the teeth either rot, known as 'meth mouth,' or need extracting. Methamphetamine may have neurological effects that do not go away if a person stops using the drug. Illicit drug manufacturers are called 'cooks. Anyone in the area of a methamphetamine laboratory is also at risk of exposure to chemicals, including children. Other health risks include a higher chance of getting a blood-borne disease, such as hepatitis , among those who inject the drug. Since the drug is illegally produced and sold, there are no controls over its contents. There is a risk of toxicity from unknown substances that may be present. Severe weight loss may occur. They may feel confused and anxious. Social consequences of long-term use include financial pressures, problems with work, and challenges with family relationships. There are currently no available medications for methamphetamine addiction. Possible strategies include behavioral approaches such as cognitive behavioral therapy CBT , family education, individual counseling, and motivational strategies, such as vouchers for those who do not use the drug for some time. Most methamphetamine is made in 'superlabs' in California or Mexico, but it can also be made in small home laboratories, using relatively inexpensive over-the-counter ingredients such as pseudoephedrine. It is often mixed with other substances, including caffeine, talc, and other toxic additives. By law, pharmacies and retail stores must keep pseudoephedrine and ephedrine products behind the counter. They also need to keep a log of consumer identification and the amount of product purchased. Commercially, methamphetamine is available under the brand name Desoxyn, in 5-mg tablets. It has a very limited use in the treatment of obesity, and attention deficit hyperactivity disorder ADHD. It is used off-label to treat narcolepsy. Article last updated by Yvette Brazier on Thu 28 June All references are available in the References tab. American Association of Neurology. Journal of Addiction Research and Therapy. Side effects of crystal meth use and abuse. What you should know. MNT is the registered trade mark of Healthline Media. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Privacy Terms Ad policy Careers. This page was printed from: Get the most out of Medical News Today. Subscribe to our Newsletter to recieve: Professionally-verified articles Daily or weekly updates Content custom-tailored to your needs Create an account. More Sign up for our newsletter Discover in-depth, condition specific articles written by our in-house team. Please accept our privacy terms We use cookies and similar technologies to improve your browsing experience, personalize content and offers, show targeted ads, analyze traffic, and better understand you. Sign in Log in with your Medical News Today account to create or edit your custom homepage, catch-up on your opinions notifications and set your newsletter preferences. Register for a free account Sign up for a free Medical News Today account to customize your medical and health news experiences. Register take the tour. Reviewed by Lindsay Slowiczek, PharmD. Table of contents What is methamphetamine? Fast facts on methamphetamine Here are some key points about methamphetamine. Methamphetamine is neurotoxic and can damage dopamine and serotonin neurons in the brain. Most methamphetamine is made illegally, and it may contain caffeine, talc, and other toxic substances. Its use is linked to higher frequencies of unprotected sexual intercourse and violent behavior. Studies suggest that it may lead to structural and functional changes in the brain associated with emotion and memory, and that some of these may be irreversible. Toxicity increases when used with alcohol, cocaine or opiates. Methamphetamine is similar to amphetamine. It is a commonly used illegal drug. Using methamphetamine can produce feelings of euphoria, but there are also dangerous side effects. Both long-term use and withdrawal can have a severe psychological and physical impact. Illegal drugs are often made in home laboratories and there is no control over the ingredients, which may be highly toxic. This content requires JavaScript to be enabled. Please use one of the following formats to cite this article in your essay, paper or report: If no author information is provided, the source is cited instead. While obesity can raise heart failure risk at any age, the risk is higher in those with a lifetime history of obesity compared with only recent obesity. Type 2 diabetes and cognitive decline: New research examines cognitive function and brain atrophy in both people with and without type 2 diabetes over the course of approximately 5 years. How to prevent festive weight gain without exercising. A new study investigates whether a simple, brief intervention might help people avoid putting on extra pounds over the holiday season. How to make kefir more healthful using sound. Kefir is credited with a range of health benefits. Recently, researchers tried to boost levels of one of its active ingredients using ultrasound. What is the best way to sober up? Can you treat opiate withdrawal symptoms at home? What you should know about date rape drugs. Subscribe Your privacy is important to us.

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