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The Lure of Ecstasy
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They skip their first class and sneak into the woods near their upscale high school. One of them takes out six rolls — six ecstasy pills — and they each swallow one. Then back to school, flying on a drug they once used only on weekends. That night they will all go out and drop more ecstasy, rolling into the early hours of another school day. A continent away in Prague, Eva, 19, is sipping a Coke at Chateau, a downtown bar. She had her first hit of ecstasy when she was All my worries seem to go away. I am just enjoying the present moment. So we know that ecstasy is versatile. The evolution of ecstasy, from an underground urban drug to an almost mundane feature of middle-class life in the U. In the U. But in the past year or so, ecstasy has returned to the American heartland; and in Europe, it has gone positively mainstream, sampled casually by suburban teens and dot com professionals alike. Established drug-running rings, most of which have their origins in Europe, have taken over the trade. Production of the drug in laboratories in the Netherlands and Eastern Europe has continued to heat up. So has smuggling: in April, Italian officials in Trieste intercepted a cache of , pills — 60, more than they picked up in all of At the height of the ecstasy craze in Europe, more than 1 million doses of e were consumed in U. While the numbers of habitual users are small, recreational rolling soars at this time of the year, when young Europeans hit the sweaty clubs in tourist meccas like Ibiza. Ecstasy use in the U. Igor, a year-old lawyer in Belgrade, has been using e for four years. On a recent Saturday night, Daniela, a year-old university student from Bologna, celebrated the end of exams with beer and pizza, then bought some ecstasy on the street and headed to Cocoric — , a pyramid-shaped superdisco. Giorgio, 19, who drove in from Milan, was offered e at a video-game arcade in Rimini that afternoon. Indeed, much of the ecstasy taking — and the law enforcement underway to end it — has been accompanied by breathlessness. At ecstasy. Ecstasy is popular because it appears to have few negative consequences. But one reason ecstasy is so fascinating is that it appears to be a safer drug than heroin and cocaine, at least in the short run, and appears to have more potentially therapeutic benefits. Even so, the U. Senate has introduced a new law under which someone caught selling about hits of ecstasy could be charged as a drug trafficker; current law sets the threshold at about , pills. A report by the British Police Federation this year recommended a loosening of penalties for ecstasy possession. Pot relaxes but sometimes confuses; lsd stupefies; cocaine wires. Ecstasy has none of those immediate downsides. All this marveling should raise suspicions, however. And even as they help open the mind to new experiences, drugs also can distort the reality to which users ineluctably return. Is ecstasy snake oil? And how harmful is it? This is what we know:. It is also unlike pretty much every other illicit drug. Ecstasy pills are or at least they are supposed to be made of a compound called methylenedioxymethamphetamine, or MDMA. Instead, its chemists simply thought it could be a promising intermediary substance that might be used to help develop more advanced therapeutic drugs. Yet MDMA all but disappeared until The cold war was on, and for years its combatants had been researching scores of substances as potential weapons. The Michigan study found that none of the compounds under review was particularly toxic — which means there will be no war machines armed with ecstasy-filled bombs. Broadly speaking, there are two dangers: first, a pill you assume to be MDMA could actually contain something else. Second, MDMA itself might do harm. The theory is that its perils spring from the same neurochemical reaction that causes its pleasures. MDMA causes these cells to disgorge their contents and flood the brain with serotonin. But forcibly catapulting serotonin levels could be risky. Of course, millions of people manipulate serotonin when they take Prozac. But ecstasy actually shoves serotonin from its storage sites, according to Dr. Normally, serotonin levels are exquisitely maintained, which is crucial because the chemical helps manage not only mood but also body temperature. At such extremes, the blood starts to coagulate. In the past two decades, dozens of users around the world have died this way. There are long-term dangers too. By forcing serotonin out, MDMA resculpts the brain cells that release the chemical. The changes to these cells could be permanent. Johns Hopkins neurotoxicologist George Ricaurte has shown that serotonin levels are significantly lower in animals that have been given about the same amount of MDMA as you would find in just one ecstasy pill. In the s, Ricaurte helped record for the first time the effects of ecstasy on the human brain. Eventually he gave memory tests to people who said they had last used ecstasy two weeks before, and he compared their results with those of a control group of people who said they had never taken e. The ecstasy users fared worse on the tests. Computer images that give detailed snapshots of brain activity also showed that e users have fewer serotonin receptors than nonusers, even two weeks after their last exposure. Ricaurte thinks the damage may be irreversible. The major problem is that his research subjects had used all kinds of drugs, not just ecstasy. And there was no way to tell that the ecstasy they had taken was pure MDMA. And critics say even if MDMA does cause the changes to the brain he has documented, those changes may carry no functional consequences. We have a lot of unanswered questions. He believes that the compound has a special ability to help people make sense of themselves and the world, that taking MDMA can lead people to inner truths. At that time, MDMA had a small following among avant-garde psychotherapists, who gave it to blindfolded patients in quiet offices and then asked them to discuss traumas. According to Shulgin, another therapist to whom he gave the drug in turn named it Adam and introduced it to more than 4, people. Manufacturers at the time flaunted the legality of the drug, promoting it as lacking the hallucinatory effects of lsd and the addictive properties of coke and heroin. But after governments in the U. She believes e enabled Shane find the right attitude to fight his illness, and she helps Doblin advocate limited legal use. Soon his association will partly fund the first approved study of MDMA in psychotherapy, involving 30 victims of rape in Spain diagnosed with post-traumatic stress disorder. In , Dr. Charles Grob, a ucla psychiatrist, who believes MDMA could be used as a pain reliever for end-stage cancer patients, concluded the drug is safe if used in controlled situations under careful monitoring. The body is much less likely to overheat in such a setting. In , emergency rooms participating in the Drug Abuse Warning Network reported receiving 1, mentions of ecstasy during admissions, compared with just in In European hotspots, such as the stretch of discos between Rimini and Riccione, Italy, 20 people are rushed to hospitals each weekend because of excessive heat, alcohol and e. The two most common short-term side effects of MDMA — both of which remain rare in the aggregate — are overheating and something harder to quantify, psychological trauma. A few users have mentally broken down on ecstasy, unprepared for its powerful psychological effects. A schoolteacher in San Francisco who took ecstasy a year ago began to recall, in horrible detail, an episode of sexual abuse. She became severely depressed for three months and had to seek psychiatric treatment. Others have suffered physical trauma. Melanie, a year-old from Lausanne, Switzerland, unknowingly consumed a drink spiked with ecstasy last summer at a club in Spain. She woke up in a hospital. Another downside: because users feel empathetic, ecstasy can lower sexual inhibitions. Men generally cannot get erections when high on e, but they are often ferociously randy when its effects begin to fade. Still, the majority of people who end up in the E. The most common adulterants in such pills are aspirin, caffeine and other over-the-counters. Contrary to lore, fake e virtually never contains heroin. But the most insidious adulterant is dxm dextromethorphan , a cheap cough suppressant that causes hallucinations in the mg dose usually found in fake e 13 times the amount in a dose of Robitussin. Because dxm inhibits sweating, it easily causes heatstroke. Another dangerous adulterant is PMA paramethoxyamphetamine , an illegal drug that in May killed two Chicago-area teenagers who took it thinking they were dropping e. Established dealers, by contrast, operate under the opposite incentive. As writer Joshua Wolf Shenk has pointed out, we tend to have opposing views about drugs: they can kill or cure; the addiction will enslave you, or the new perceptions will free you. Aldous Huxley typified this duality with his two most famous books, Brave New World — about a people in thrall to a drug called soma — and The Doors of Perception — an autobiographical work in which Huxley begins to see the world in a brilliant new light after taking mescaline. Ecstasy can occasionally enslave and occasionally offer transcendence. Usually, it does neither. For Adrienne, an American woman who has been a frequent user for the past five years, ecstasy is a key part of life. I allowed myself to get closer to people. Everything was more positive. Contact us at letters time. Join Us. Customer Care. Reach Out. Connect with Us. Is Adrenal Fatigue Real? Home U. All Rights Reserved. TIME may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.
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The Lure of Ecstasy
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