Rhiannon Bray
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Imperial College London | Imperial · Urogynaecology
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Introduction: Polyacrylamide hydrogel periurethral injection is used as one of the many injectable agents available to manage stress urinary incontinence [1]. Bulking agents are a minimally invasive low risk alternative to synthetic slings. Raised awareness of complications associated with mesh procedures and the recent controversy in the UK regard...
Urethral bulking agents (UBAs) to treat stress urinary incontinence was first described in the 1930s, when paraffin was used to increase urethral resistance. Since then, several agents have been introduced to the market, with varying degrees of safety, efficacy, and durability. The agents currently available include calcium hydroxyl apatite (Coapti...
A number of outcome measures can be used when considering the surgical treatment of pelvic organ prolapse (POP).
Lower urinary tract symptoms (LUTS), including urinary incontinence, urgency and nocturia, affect approximately half of women worldwide. Current diagnostic methods for LUTS are invasive and costly, while available treatments are limited by side effects leading to poor patient compliance. In this study, we aimed to identify urine metabolic signature...
Aims: We evaluated the effect of Tolterodine extended release (TER) versus placebo on bladder wall thickness (BWT) using transvaginal ultrasound in women with overactive bladder (OAB). Materials and methods: We recruited 79 women with symptoms of OAB with a mean age of 47 years who had a BWT of at least 5 mm and a post-micturition volume of less...
Objective: It is unclear if any catheterisation is necessary after vaginal surgery for pelvic organ prolapse. The aim of this study was to determine if indwelling catheterisation is necessary after these procedures. Study design: A randomised controlled trial of immediate post-operative removal of catheter compared to a suprapubic catheter (SPC)...
Introduction and hypothesis: The pathophysiology of prolapse is not well understood. However, two main theories predominate: either the fibromuscular layer of the vagina develops a defect/tears away from its supports, or its tissues are stretched and attenuated. The aim of this study was to assess how vaginal wall thickness (VWT) is related to vag...
The contribution of pelvic floor muscle tenderness to chronic pelvic pain (CPP) is well established in the literature. However pelvic floor muscle hyperalgesia (PFMH) is often missed during vaginal examination of women with CPP. To our knowledge criteria for diagnosing PFMH has not been established or validated so far. The aim of this study is to a...
Urogynaecology
London, United Kingdom
Division of Computational and Systems Medicine (CSM)
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