Recent Slits Get Examined
Recent slits get examined Oct 01, · Oct 01, · The genes encoding Slits and their Robo receptors are silenced in many types of cancer, including breast, suggesting a role for this signaling pathway in suppressing tumorigenesis. The molecular mechanism underlying these tumor-suppressive effects has not been delineated. Here, we show that loss of Slits, or their Robo1 receptor, in murine mammary gland or Cited by:
Aug 17, · Aug 17, · A growing number of recent studies suggest that Slit-Robo signaling also has potent, we examined the effect of NSlit2 on constitutive macropinocytosis. P. Cited by: 6.
Dec 08, · Dec 08, · Here the authors find that PlexinA1, a well-known Semaphorin receptor, is also a receptor for Slits. Utilizing phenotypic analysis of mouse models, they define an in vivo contribution of Plexin Cited by:
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May 27, · Results and discussion. SLITs/ROBOs are reported to be involved in the formation of hippocampal connections during the rodent development [].We examined the SLIT and ROBO mRNA expression patterns in the hippocampus and its surrounding areas in the adult macaques (Additional file 1: Figure S1).. In and around the hippocampus, all the SLIT and ROBO mRNAs were widely .
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Sep 02, · Sep 02, · A laser beam shined a light across the slits while a cell phone camera was positioned on the back of the box. Study participants were then asked to speak through the hole while the cell phone recorded the way the light moved in .
Apr 16, · Apr 16, · The New York Times. By Richard B. Woodward. April 16, This cover story appeared in the magazine on Sept. 27, , and is discussed in an article by Sally Mann in the April 19 issue. At the Missing: slits.
Sep 09, · Sep 09, · However, recent analyses of compound mutant mice reveal that additional Slit receptors must be expressed by commissural axons to account for their Slit-mediated repulsion from the midline. In the absence of Robo-3 commissural axons fail to cross the midline, presumably due to the elevated expression of Robo-1/−2 on pre-crossing axons [8].
Oct 08, · Oct 08, · SLITs Accelerate Ca 2+ Oscillations and Modulate ER Luminal Ca 2+. Ca 2+ homeostasis, especially within the ER, plays a key role in both beta-cell survival (24, 25, 27, 28) and glucose responsiveness (27, 29, 30). Given that SLIT2 signaling in neurons involves Ca 2+ release from the ER (31 –33), we examined this.
Oct 28, · Oct 28, · The mechanical sensitivities of the two slits examined in this organ in detail differed roughly threefold ( and nm mN−1) in the biologically most relevant range, again reflecting stimulus.
Apr 04, · Apr 04, · As these secondary slits extend, the primary slits move ventrally and eventually come to lie on the left side of the head, such that the final adult morphology has symmetrical gill slits. This has led to an assumption, dating from the s, that the slits that lie on the right side of the larval head are in fact homologous to the left-sided.
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