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Repetitive weekly and monthly use is linked to GI and heart issues. If you have chronic pain , chances are you've turned to nonsteroidal anti-inflammatory drugs NSAIDs for pain relief on more than one occasion. However, chronic or long-term use of NSAIDs—defined as more than three times a week for more than three months—can have negative health effects. This article discusses the use of NSAIDs like ibuprofen and naproxen for chronic pain, how these drugs work, and how to take them. Nonsteroidal anti-inflammatory drugs, or NSAIDs, are pain medications often used to treat muscle and joint pain, though they may be used for nerve pain in some cases. NSAIDs fall under the heading of non-opioid analgesics or non-narcotic pain medications. NSAIDs reduce pain in two ways. First, they alter the sensation of pain by blocking certain enzymes that participate in the pain response. Second, they work to reduce swelling that is often associated with certain types of pain. Most NSAIDs are taken by mouth, and their strength varies depending on the type of medication and dosage used. When you take NSAIDs for chronic pain, you may take a short-acting version combined with long-acting pain medication, such as an opioid or an adjuvant analgesic an anticonvulsant or an antidepressant. This is especially true if you have breakthrough pain. Some of the more commonly available over-the-counter NSAIDs for chronic pain include aspirin , ibuprofen, and naproxen. These pain medications are sold in different non-prescription strengths and may be combined with other ingredients, such as caffeine or acetaminophen. When NSAIDs are used regularly over an extended period of time, as is often the case with chronic pain, the potential for side effects increases. Some more common side effects include:. If you plan to be on NSAIDs for chronic pain long-term, your healthcare provider may alter the dosage. He or she may also provide you with other prescription medication that offsets the potential for developing any of the above conditions. Long-term or chronic use is defined as taking NSAIDs more than three times a week for more than three months. NSAIDs are fine to take on occasion, but long-term daily use can lead to side effects including stomach ulcers and gastric bleeding. If you have ongoing pain concerns and find yourself reaching for an NSAID every day, talk to your doctor about other options for managing your pain. Ibuprofen has the lowest risk of liver damage. Trends in the use of aspirin and nonsteroidal anti-inflammatory drugs in the general U. Pharmacoepidemiol Drug Saf. Merck Manual Professional Version. Treatment of pain. Cleveland Clinic. J Precision Med. Use limited data to select advertising. Create profiles for personalised advertising. Use profiles to select personalised advertising. Create profiles to personalise content. Use profiles to select personalised content. Measure advertising performance. Measure content performance. Understand audiences through statistics or combinations of data from different sources. Develop and improve services. Use limited data to select content. List of Partners vendors. Chronic Pain. By Erica Jacques. Medically reviewed by Femi Aremu, PharmD. Table of Contents View All. Table of Contents. Is Long-Term Use Safe? Frequently Asked Questions. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. See Our Editorial Process. Meet Our Medical Expert Board. Share Feedback. Was this page helpful? Thanks for your feedback! What is your feedback? Related Articles. You may accept or manage your choices by clicking below, including your right to object where legitimate interest is used, or at any time in the privacy policy page. These choices will be signaled to our partners and will not affect browsing data.

Addiction: what is it?

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Back to Addiction support. Addiction is defined as not having control over doing, taking or using something to the point where it could be harmful to you. Addiction is most commonly associated with gambling , drugs , alcohol and smoking , but it's possible to be addicted to just about anything, including:. There are lots of reasons why addictions begin. In the case of drugs, alcohol and nicotine, these substances affect the way you feel, both physically and mentally. These feelings can be enjoyable and create a powerful urge to use the substances again. Gambling may result in a similar mental 'high' after a win, followed by a strong urge to try again and recreate that feeling. This can develop into a habit that becomes very hard to stop. Being addicted to something means that not having it causes withdrawal symptoms, or a 'come down'. Because this can be unpleasant, it's easier to carry on having or doing what you crave, and so the cycle continues. Often, an addiction gets out of control because you need more and more to satisfy a craving and achieve the 'high'. The strain of managing an addiction can seriously damage your work life and relationships. In the case of substance misuse for example, drugs and alcohol , an addiction can have serious psychological and physical effects. Some studies suggest a person's risk of becoming addicted is partly genetic, but environmental factors, such as being around other people with addictions, are also thought to increase the risk. Behaviours such as substance misuse can be a way of blocking out difficult issues. Unemployment and poverty can trigger addiction, along with stress and emotional or professional pressure. Addiction is a treatable condition. Whatever the addiction, there are lots of ways you can seek help. You could see your GP for advice or contact an organisation that specialises in helping people with addictions. You can use the following online directories to find addiction treatment services in your area:. To speak to someone anonymously about any type of addiction, you can call the Samaritans free on Page last reviewed: 23 July Next review due: 23 July Addiction: what is it? Addiction is a common problem, but help is available. How addictions can affect you The strain of managing an addiction can seriously damage your work life and relationships. Getting help for addictions Addiction is a treatable condition. You can use the following online directories to find addiction treatment services in your area: alcohol addiction support services drug addiction support stop smoking clinics smoking cessation To speak to someone anonymously about any type of addiction, you can call the Samaritans free on

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