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Psilocybe is a genus of gilled mushrooms growing worldwide. This genus is best known for the species with psychedelic properties. Psilocybin , psilocin and baeocystin are the main psychedelic compounds responsible for the psychoactive effects of many species in the genus. The final e is not silent. Psilocybe fruit bodies are typically small, nondescript mushrooms with a typical ' little brown mushroom ' morphology. Macroscopically, they are characterized by their small to occasionally medium size, brown to yellow-brown coloration, with a typically hygrophanous cap , and a spore print -color that ranges from lilac-brown to dark purple-brown though rusty-brown colored varieties are known in at least one species. Microscopically, they are characterized by pileipellis with hyphae that run parallel to the pileus surface, forming a cutis , by their lack of chrysocystidia , and by spores that are smooth, ellipsoid to rhomboid to subhexagonal in shape, with a distinct apical germ pore. Ecologically, all species of Psilocybe are saprotrophs , growing on various kinds of decaying organic matter. A study of the molecular phylogeny of the agarics \\\\\\\\\\\\\[7\\\\\\\\\\\\\] indicated that the genus Psilocybe as then defined was polyphyletic , falling into two distinct clades that are not directly related to each other. The blue-staining hallucinogenic species constituted one clade and the non-bluing species the other. The previous type species Psilocybe montana of the genus was in the non-bluing clade, but in the type species was changed to Psilocybe semilanceata , a member of the bluing clade. A molecular phylogenetic study of the Agaricales by Matheny and colleagues, further demonstrated the separation of the bluing and non-bluing clades of Psilocybe in a larger, strongly supported phylogenetic tree of the Agaricales. Psilocybe had been placed taxonomically in the agaric family Strophariaceae based upon its spore and pileipellis morphology. The phylogenetic study by Matheny et al. The bluing Psilocybe , however, form a clade that is sister to Galerina in the newly revised family, Hymenogastraceae that used to be restricted to secotioid, false-truffles. In , a paper by Redhead et al. Geographically, species in this genus are found throughout the world in most biomes. Many of the species found in temperate regions, such as Psilocybe cyanescens , seem to have an affinity for landscaped areas mulched with woodchips and are actually rather rare in natural settings removed from human habitation. Contrary to popular belief, only a minority of Psilocybe species, such as P. The psilocybin molecule is indirectly responsible for the hallucinogenic properties of the Psilocybe. This compound, as well as all other indole alkaloids, are derived from the amino acid tryptophan , being the only amino acid with the indole-amine ring. Tryptophan is converted to tryptamine by decarboxylation. This blue-staining reaction occurs after the fruit body has been injured, particularly near the base of the stalk. The chemical structure of serotonin , an innate indole alkaloid neurotransmitter that regulates our mood and therefore happiness, is nearly identical to that of psilocin. The latter differing mainly by the hydroxyl group moving one carbon and the addition of two methyl groups that make the molecule lipophilic fat soluble , ergo capable of crossing the lipid membrane sheaths of the central nervous system. This effect explains the euphoria experienced by ingestion of this 'agonist'. Initially, hallucinogens were thought to blockade these serotonin neurotransmitters, but persistent research led to this agonist effect conclusion. Woolley and Campbell conducted research to determine whether the depletion of the hormone serotonin had a direct effect on mental disorders and that hallucinations might be due to an excess of serotonin. They found that the psychoactive chemicals psilocybin and psilocin exhibited serotonin-like effects, however as dosage increased, these compounds acted as serotonin antagonists, psilocybin being comparable to the most potent antagonist yet discovered. Even though these chemicals are psychoactive and therefore the basidiomycete deemed toxic, there have been no reports of fatalities or induced internal organ damage directly associated with ingestion of these chemicals. Some psychoactive species contain baeocystin and norbaeocystin in addition to psilocin and psilocybin. Shamans, or curanderas would avidly ingest the 'sacred mushrooms' for the extrasensory perceptual effects it gave them in order to better assess problems faced in their society. Hallucinogenic species of Psilocybe have a long history of use among the native peoples of Mesoamerica for religious communion, divination, and healing, from pre-Columbian times up to the present day. After the Spanish conquest of the Americas , the use of hallucinogenic plants and mushrooms, like other pre- Christian traditions, was forcibly suppressed and driven underground. By the 20th century, hallucinogenic mushroom use was thought by non- Native Americans to have disappeared entirely. However, in , Valentina Wasson and R. Gordon Wasson became the first Westerners to actively participate in an indigenous mushroom ceremony. The Wassons did much to publicize their discovery, even publishing an article on their experiences in Life in The species identified by Heim were; Psilocybe mexicana, P. At present, hallucinogenic mushroom use has been reported among a number of groups spanning from central Mexico to Oaxaca, including groups of Nahua , Mixtecs , Mixe , Mazatecs, Zapotecs , and others. The popularization of entheogens by Wasson, Timothy Leary , and others has led to an explosion in the use of hallucinogenic Psilocybe throughout the world. By the early s, a number of psychoactive Psilocybe species were described from temperate North America, Europe, and Asia and were widely collected. Books describing methods of cultivating Psilocybe cubensis in large quantities were also published. The relatively easy availability of hallucinogenic Psilocybe from wild and cultivated sources has made it among the most widely used of the hallucinogenic drugs. The purified chemicals psilocybin and psilocin are listed as Schedule I drugs under the United Nations Convention on Psychotropic Substances. Internationally, the two chemicals are generally considered controlled substances. However, there is much ambiguity about what is considered a 'container' of these compounds in several countries e. Brazil , the chemicals themselves are listed as controlled substances, but the mushrooms that contain the chemicals are not, therefore deemed legal. This is because the Supreme Court of Florida does not believe that these mushrooms could 'reasonably be found to be containers of the schedule I substance, psilocybin'. In the United States there is no federal law mentioning the possession of Psilocybe spores, this is because only the psilocybin and psilocin compounds are considered Schedule I drugs and there is no presence of these compounds in the spores themselves, only in the fruiting body of the cultivated spores. However, there are several US states that have actually prohibited possession of these spores because they can be cultivated to produce these hallucinogenic, Schedule I drugs. These states includes California, Georgia, \\\\\\\\\\\\\[38\\\\\\\\\\\\\] and Idaho. However, possession of the spores by a qualified mycologist in California is legal if being put to use for research purposes, which must be approved by Research Advisory Panel. Psilocybin mushrooms as well as other 'soft drugs' which are stronger than cannabis but not synthetic, are legally available through smart shops in The Netherlands. Only the truffle form of magic mushrooms such as Psilocybe tampanensis are currently legal, but these still contain the active ingredients and produce similar effect as the caps and stalks. Except for ornamental purposes, growing, selling or possessing Psilocybe spp. From Wikipedia, the free encyclopedia. Psilocybe Psilocybe semilanceata Scientific classification Kingdom: Legal status of psilocybin mushrooms. List of Psilocybe species. Farlex Partner Medical Dictionary. Retrieved 18 June Genesis of the PF Redspore psilocybe. Molecular Phylogenetics and Evolution. Archived from the original PDF on Retrieved November 28, Annali del Museo Civico di Rovereto. Journal of Pharmaceutical Sciences. In general, the less psilocin there is in a species, the more subtle the bluing reaction. Retrieved 28 November American Association for the Advancement of Science. New York, New York: Annual Review of Pharmacology and Toxicology. Gordon Wasson au cours de leurs missions de et dans les pays mije, mazateque, zapoteque et nahua du Mexique meridional et central'. Retrieved 5 December Regulatory Toxicology and Pharmacology. John Wiley and Sons. A Colour Atlas of Poisonous Fungi: Mushroom hunting mushroom poisoning list of deadly fungus species list of poisonous fungus species list of psilocybin mushrooms legal status isoxazole mushrooms psilocybin mushrooms. Retrieved from ' https: Entheogens Psilocybe Psychoactive fungi Psychedelic tryptamine carriers. Views Read Edit View history. In other projects Wikimedia Commons Wikispecies. This page was last edited on 25 November , at By using this site, you agree to the Terms of Use and Privacy Policy. Wikimedia Commons has media related to Psilocybe. Wikispecies has information related to Psilocybe.

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