Prozac Sexual Side Effects
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Prozac Sexual Side Effects
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"My libido is down and I've recently started taking Prozac (Fluoxetine). Are the two related?"
Yes, decreased libido or sex drive is a very common side effect of this popular drug. In fact, 11% of patients, both male and female, reported this symptom. There are several other side effects of Prozac in women as well.
You might consider switching to Zoloft. It has a lower side effect profile, overall. Although it does still have the problems with decreased libido, it is possible to get around this because it stays in the body a shorter amount of time it is possible to take a "drug holiday." If you discontinue the drug for a weekend (2-4 days), your normal sex drive and response will return, quickly. The drug can be resumed after short periods without a loss of clinical effectiveness.
Prozac is used in depression and obsessive/compulsive disorders . Both of these are more common in women, so it is more likely women will be on the drug.
Infrequent is defined as 1 out of 100 (or 1%) to 1 out of 1000 (.1%):
Leukorrhea (white or yellow discharge from the vagina)
Menorrhagia (Excessive menstrual bleeding)
Rare was defined less than 1 out of 1000 (.1%):
Abortion (spontaneous loss of a pregnancy or conception)
Dyspareunia (Pain during intercourse)
Lactation (Milk production from the breasts)
Hypomenorrhea (Decreased menstrual bleeding)
Metrorrhagia (bleeding between periods)
Salpingitis (Inflammation of the Fallopian tubes, which carry the egg from the ovary to the uterus)
Prozac is a Class B drug for pregnancy. That means that the drug should be taken in pregnancy only if it is clearly needed. Inform your doctor is you are, plan to be, or do become pregnant on Prozac. The same applies to breastfeeding.
APA Reference Staff, H.
(2021, December 21). Prozac: Side Effects for Women, HealthyPlace. Retrieved
on 2022, July 10 from https://www.healthyplace.com/sex/medications/prozac-side-effects-for-women
Medically reviewed by Harry Croft, MD
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“I was raped by my ex-boyfriend on Prozac.”
After hearing the reports that a drug like Prozac can produce unwanted sexual side effects, I was surprised to be raped by my ex-boyfriend who had been taking prescription Prozac for at least a couple of years. We had broken up and were attempting to do the “friend thing” by talking about our differences and maintaining some form of connection.
When I met with his mother (who I had befriended before our relationship) after our break up and my rape experience, she asked me if he was ever pushy or inappropriate with me sexually, which indicated to me she knew he had this tendency of behavior.
I also realize that many factors impact a person who rapes, but I can’t help but wonder if there is some relationship between Prozac and his sexual behavior.
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Briefly, what are the effects of Prozac on libido?
Prozac can affect each person's libido differently, ranging from significant and noticeable change to no change at all. However the general trend is that rather than sparking spontaneous sexual escapades, Prozac has been associated with a decreased libido, difficulty in reaching orgasm, and for some men, difficulty maintaining erections. Between feast and famine, the leaning would be toward famine. Selective serotonin reuptake inhibitors (SSRIs), the class of drugs to which Prozac belongs, often do cause sexual complications. But, it doesn't have to be that way.
If taking Prozac, and concerend about sexual side effects, health care providers can modify dosage to lessen the libido-decreasing effects of Prozac. A provider may also be able to prescribe a medication to combat this unwanted side effect. Antidepressants like Wellbutrin or Remeron are not part of the SSRI family, are not known to cause sexual side effects, and could be an option — a prescribing health care provider will have the best information.
To discuss treatment of depression or anxiety, make an appointment with a mental health care specialist, or talk to a health care provider for a referral. For more information and tips on coping with the side effects of antidepressants, check out the Mayo Clinic . In addition, the related Q&A's linked may also shed some light on other ways to deal with this phenomenon.
Many medications can have unwanted side effects. It's smart for consumers to learn about the range of possible side effects for a given medication, so that together with a provider they can make educated choices.
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The popular medications known as selective serotonin reuptake inhibitors or SSRIs (see box) can help lift people out from under a dark cloud of depression. But there are some side effects from antidepressants , including those that can affect your sex life. In addition to reducing interest in sex, SSRI medications can make it difficult to become aroused, sustain arousal, and reach orgasm. Some people taking SSRIs aren't able to have an orgasm at all. These symptoms tend to become more common with age.
If you experience any sexual problems while taking an SSRI medication, talk with your doctor or therapist. About 35% to 50% of people with untreated major depression experience some type of sexual dysfunction prior to treatment. So, in some cases, sexual difficulties may stem not from the SSRI, but rather from the underlying depression. If medication is the problem, sexual side effects sometimes subside with time, so it's worth waiting a while to see if problems diminish. This is a particularly good strategy if the medication is easing your depression significantly. But if side effects from antidepressants persist, your doctor or therapist may suggest one of the following strategies, as found in the Harvard Special Health Report Understanding Depression :
Lowering the dose. Sexual side effects may subside at a lower, although still therapeutic, dose.
Scheduling sex. Your medication may produce more pronounced side effects at particular times of the day, for example, within a few hours of taking it. If so, you can try scheduling sexual activity for the time when side effects are least bothersome—or take the drug at a different time.
Taking a drug holiday. Depending on how long the drug usually remains in your body, you might stop taking it for a few days—for example, before a weekend, if that's when you hope to have sex. This isn't spontaneous, but it can work if you carefully follow your doctor's directions about how to stop and resume your medication. However, there is always a chance that this might cause a relapse, especially if it is one of the drugs that leaves your system relatively rapidly.
Switching to a different drug. Certain antidepressants, such as bupropion (Wellbutrin), and mirtazapine (Remeron) are less likely to cause sexual problems. Bupropion, which affects both norepinephrine and dopamine, can sometimes improve sexual response.
Adding a drug. For some men, taking sildenafil (Viagra) or tadalafil (Cialis) can alleviate SSRI-induced erectile dysfunction . Both men and women may benefit from adding bupropion to their treatment. This medication has been found to counter SSRI-induced sexual dysfunction, boost sexual drive and arousal, and increase the intensity or duration of an orgasm. In some people, the anti-anxiety drug buspirone (BuSpar) may help increase libido and restore the ability to have an orgasm.
Meeting with a therapist. Even when physical issues or medication are at the root of sexual problems, psychological issues often become interwoven. For example, a few episodes of erectile dysfunction may cause a man to withdraw from sex and his partner to feel rejected. These issues can lead the couple to retreat further from intimacy. Working with a sex therapist or general therapist can help couples explore their sexual concerns, learn to better communicate, and expand their repertoire of sexual activities.
– By Julie Corliss
Executive Editor, Harvard Heart Letter
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