Prozac Sex Drive

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"My libido is down and I've recently started taking Prozac (Fluoxetine). Are the two related?"
Yes, decreased libido or sex drive is a very common side effect of this popular drug. In fact, 11% of patients, both male and female, reported this symptom. There are several other side effects of Prozac in women as well.
You might consider switching to Zoloft. It has a lower side effect profile, overall. Although it does still have the problems with decreased libido, it is possible to get around this because it stays in the body a shorter amount of time it is possible to take a "drug holiday." If you discontinue the drug for a weekend (2-4 days), your normal sex drive and response will return, quickly. The drug can be resumed after short periods without a loss of clinical effectiveness.
Prozac is used in depression and obsessive/compulsive disorders . Both of these are more common in women, so it is more likely women will be on the drug.
Infrequent is defined as 1 out of 100 (or 1%) to 1 out of 1000 (.1%):
Leukorrhea (white or yellow discharge from the vagina)
Menorrhagia (Excessive menstrual bleeding)
Rare was defined less than 1 out of 1000 (.1%):
Abortion (spontaneous loss of a pregnancy or conception)
Dyspareunia (Pain during intercourse)
Lactation (Milk production from the breasts)
Hypomenorrhea (Decreased menstrual bleeding)
Metrorrhagia (bleeding between periods)
Salpingitis (Inflammation of the Fallopian tubes, which carry the egg from the ovary to the uterus)
Prozac is a Class B drug for pregnancy. That means that the drug should be taken in pregnancy only if it is clearly needed. Inform your doctor is you are, plan to be, or do become pregnant on Prozac. The same applies to breastfeeding.
APA Reference Staff, H.
(2021, December 21). Prozac: Side Effects for Women, HealthyPlace. Retrieved
on 2022, July 10 from https://www.healthyplace.com/sex/medications/prozac-side-effects-for-women

Medically reviewed by Harry Croft, MD
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I know that you've briefly addressed the use of Prozac and its effects on the male libido, but I was wondering if you could comment in a bit more detail on its use by men to help them maintain a strong libido and increased control of release. I've heard recent stories about how a "very small" amount of Prozac can have a very dramatic result in increased control for the male — to the point of providing his partner with the best sex of their relationship... Could you comment? What are the dosages typically used for this purpose, and are there any major side effects?

Prozac, generically known as fluoxetine, is the world's most widely prescribed anti-depressant; currently, more than 54 million people all over the globe use this medication to treat depression, panic disorder, obsessive-compulsive disorder, and bulimia nervosa. Fluoxetine works by normalizing the levels of the neurotransmitter serotonin in the brain. This provides freedom from constant negative thoughts, sadness, suicidal thoughts, low energy, negative self-image, pervasive thoughts of needing to perform a specific act, and overwhelming feelings of dread and fear. Contrary to what you've heard, fluoxetine does not increase libido. Actually, it usually reduces sexual desire or drive and inhibits orgasm, or the reflex of a sexual release; as a result, some men use fluoxetine recreationally to delay ejaculation.

However, if someone thinks there is a problem with premature ejaculation, they may want to see a health care provider, such as a urologist, who can suggest an appropriate treatment regimen. Selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine and Paxil (generically known as paroxetine), are prescribed by some medical providers for premature ejaculation. These drugs, often used in conjunction with sex therapy, can address this. Some sex therapists also use Eastern disciplines, such as Tantra, for maintaining erections and lasting longer during sex.

From your question, it's not clear if you are asking about the use of fluoxetine as an anti-depressant, or just curious about having it as a tool in one's sexual shed. Based on the info offered here, recreational use of fluoxetine by someone who does not experience premature ejaculation will neither allow for greater ejaculatory control or stamina, nor provide their "partner with the best sex of their relationship." In addition, what one considers the best sex, another may not. Plus, this pressure over pleasure creates an undue expectation, excluding other essentials that enhance sexual experiences. What about the feelings involved in being wanted, desired, lusted after? What about tender touching and caressing? Lasting longer is not the only or primary factor in satisfying a partner sexually.
If you are in an urgent situation, please visit our Emergency page to view a list of 24 hour support services and hotlines.

Part of HuffPost Wellness. ©2022 BuzzFeed, Inc. All rights reserved.
Antidepressants Can Lower Your Sex Drive. Here's How To Fix It.
Experts break down everything you need to know.
Jun 1, 2018, 07:06 PM EDT | Updated Jun 5, 2018
Your brain might be to blame for your lack of sex drive.
The dip in your libido might not last.
Men are more likely to experience a change in their sex drive.
Be mindful of other factors that could get in the way.
Chat with a physician about tweaking your medication.
Above all, be honest with your doctors about the issue.
Celebrities On The Importance Of Mental Health See Gallery
Part of HuffPost Wellness. ©2022 BuzzFeed, Inc. All rights reserved.
For the more than 16 million Americans living with depression, antidepressants are often an option in providing some relief from their symptoms. However, as with any new medication, side effects are common. And that means for some, sex is impossible.
Antidepressants, particularly selective serotonin reuptake inhibitors, or SSRIs, have been shown to impact one sex’s drive ― with symptoms like reduced libido, delayed ejaculation, erectile dysfunction and an inability or delayed ability to reach orgasm. But there’s no definitive answer on how common those issues are for users. The results of studies vary widely, with the estimated of number of people affected ranging from 25 percent to 73 percent of those who take the drugs, according to Ash Nadkarni, associate psychiatrist at Brigham and Women’s Hospital in Boston.
This doesn’t mean that all hope is lost or that you should necessarily find alternative methods of mental health treatment. As with most health-related medication, knowledge is power. Below, experts break down what you need to know about antidepressants and your sex drive, and what you can possibly do about it:
Nadkarni said the potential sexual impact of SSRIs may lie in specific chemical occurrences in the brain.
“Pathways of sexual desire involve serotonin, but also chemicals such as dopamine and norepinephrine,” she said. “Dopamine is linked to the intense passion and arousal of romantic love, while norepinephrine is associated with the heightened attention and motivation of desire. Serotonin-enhancing antidepressants blunt sexual desire by reducing the capacity of dopamine and norepinephrine, or excitatory pathways, to be activated.”
Despite serotonin’s ability to lessen sexual desire, Nadkarni noted that in some instances, the chemical can also increase desire. It really varies depending on the person and the type of depression medication one is taking. For instance, some medications, including Viibryd and Wellbutrin , have been lauded for their lack of sexual side effects.
The changes antidepressants can cause in one’s sexual desire or experience of sex aren’t always permanent. It can also be difficult to determine whether depression or antidepressants are the reason for someone’s decreased sexual drive, according to John Christman, a psychiatrist at Zucker Hillside Hospital in Glenn Oaks, New York.
“When people are depressed they tend to be less social and interactive, and of course, that can have its effects in terms of libido,” Christman said. “It’s interesting because we always warn patients before starting antidepressants that one side effect of the medication can be sexual dysfunction. However in many patients their sexual performance improves because they’re less depressed.”
The sexual improvement felt by some patients beginning antidepressants isn’t necessarily the experience of all. Christman explained that sexual dysfunction is the most commonly experienced side effect of antidepressants, especially in men. Those who experience sexual dysfunction as a result of their antidepressants may consider stopping their medication, but Christman cautions against that.
“I tell most of my patients to try your best to wait it out,” he said. “If you give the medication a little bit of time, in many cases, the dysfunction will improve.”
So, what can you do about all of it? Here are a few solutions:
Sometimes, it’s not just your medication coming into play. Nadkarni said it’s important to be aware of other possible causes of sexual side effects, including age, alcohol usage, other medications or any leftover symptoms of depression.
There are multiple ways of working through any sexual side effects, including switching medications, incorporating an additional medication, or taking a day off from your medication. But this “drug holiday,” as Christman calls it, should only be done with the approval and supervision of your doctor.
“Wait the symptoms out and many times it does get better,” Christman said. “It’s very important to have conversations with your doctor if you’re experiencing side effects. Don’t feel embarrassed. Sexual activity is normal human behavior not to be stigmatized.”
Before you reconsider taking antidepressants, or attempt to stop using them if side effects arise, you should speak with your physicians who prescribed you the medication.
Those on antidepressants and experiencing a decreased sex drive also may want to consider speaking with a sex therapist.
“I suggest joint couples or sex therapy sessions (separate from the person with depression’s personal therapy) so you can feel like you’re both being heard, and so you can work together as a team on your sex life,” sex therapist Vanessa Marin said. “The tricky thing about these situations is that you have to make the space for both of your experiences. It’s understandable for the person with depression to be disinterested in sex, and it’s understandable for the partner to still want sex. You may have to be patient for a while, and you may have to get creative about other ways to experience intimacy and sexual satisfaction.“
How you choose to address any side effects that might arise from taking a depression medication remains up to you. And keep in mind that not every person will have the same experience.
“If you do have the side effects sometimes with time it will go away, and if it still doesn’t go away there are things you can do,” Christman said. “Not everybody gets the side effects, and you should not let the sexual side effects be a stumbling block in seeking treatment. It’s something to be discussed with your doctor, and it’s something you can treat together.”

Published October 26, 2015 6:32pm EDT
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