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The transition zone is found on the inside of the gland and is the smallest part of the prostate (about 10%). It surrounds the urethra between the bladder and the upper third of the urethra.
The central zone surrounds the transition zone and makes up about one quarter of the prostate’s total mass. This is where the duct common to the prostate, seminal duct and the seminal vesicles is found. This duct is also known as the ejaculatory duct (Ductus ejaculatorius).
The peripheral zone represents the main part of the prostate gland – about 70% of the tissue mass is part of the peripheral zone.
One part of the semen is produced in the prostate. Together with sperm cells from the testicles, fluid from the seminal vesicle and the secretions released by another pea-sized gland below the prostate (the bulbourethral gland), the prostate fluid makes up the semen. All of these fluids are mixed together in the urethra.
The prostatic secretion is important for the proper functioning of the sperm cells, and therefore also for fertility in men. The thin, milky liquid contains many enzymes such as the prostate-specific antigen (PSA). This enzyme makes the semen thinner.
The hormone-like substance spermine mostly ensures sperm cell motility (ability to move).
Menche N. (ed.) Biologie Anatomie Physiologie. Munich: Urban & Fischer/ Elsevier; 2012.
Pschyrembel W. Klinisches Wörterbuch. Berlin: De Gruyter; 2014.
Schmidt R, Lang F, Heckmann M. Physiologie des Menschen: mit Pathophysiologie. Heidelberg: Springer; 2011.
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InformedHealth.org [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. How does the prostate work? 2011 Feb 15 [Updated 2016 Aug 23]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279291/
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Created: February 15, 2011 ; Last Update: August 23, 2016 ; Next update: 2020.
The prostate is a gland about the size of a chestnut and weighs about 30 grams (about 1 ounce). It is part of the male reproductive system and is located inside the body. The prostate’s most important function is the production of a fluid that, together with sperm cells from the testicles and fluids from other glands, makes up semen. The muscles of the prostate also ensure that the semen is forcefully pressed into the urethra and then expelled outwards during ejaculation.
The prostate is located directly below the bladder and above the muscles of the pelvic floor. The rectum is behind the prostate, making it possible to feel the gland from the rectum using the finger. The ducts in the prostate gland flow into the urethra, which passes through the prostate. The word “prostate” is taken from the Greek expression meaning “one who stands before,” which describes the position of the prostate gland. Viewed from below, where the urethra leaves the gland, the prostate “stands before” the bladder.
The prostate gland is surrounded by a capsule of connective tissue containing many smooth muscle fibers and elastic connective tissue, which is why it feels very elastic to the touch when it is examined. There are also many smooth muscle cells inside of the prostate. During ejaculation these muscle cells contract and forcefully press the fluid that has been stored in the prostate out into the urethra. This causes the fluid and the sperm cells, together with fluid from other glands, to combine to form semen, which is then released.
The tissue of the prostate gland can be divided into three different zones, listed here from innermost to outermost, which encircle the urethra like layers of an onion:
The transition zone tissue tends to undergo benign (non-cancerous) growth in old age.The medical term for this is benign prostatic hyperplasia (BPH). If this tissue presses against the bladder and the urethra, it can lead to difficulties urinating. This is a common problem among older men. Malignant (cancerous) tumors in the prostate mostly develop in the peripheral zone instead.
The prostate has various functions:
Closing of the urethra up to the bladder during ejaculation: During ejaculation the prostate and the bladder’s sphincter muscle close the urethra up to the bladder to prevent semen from entering the bladder. Closing of the seminal ducts during urination: During urination the central zone muscles close the prostate’s ducts so that urine cannot enter.
Hormone metabolism: In the prostate the male sex hormone testosterone is transformed to a biologically active form, DHT (dihydrotestosterone).
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The prostate is an important gland located between the penis and bladder . It sits just to the front of the rectum. The urethra , which carries urine from the bladder out of the body, runs through the center of this walnut-sized organ.
The gland's primary function is to secrete fluid that nourishes sperm and keeps it safe. 1
Some health conditions that affect the prostate include: 2
This article explains the anatomy, function, and common conditions of the prostate and some common tests associated with the organ.
The prostate is located within the lower pelvis. It sits just beneath the bladder and to the front of the rectum.
The prostate is surrounded by a fibrous tissue called the capsule. It wraps around the urethra. The seminal vesicles run above and behind this gland. 3
Its shape is cone-like. The base of the prostate surrounds the neck of the urinary bladder, and the apex (highest point) sits below the sphincter.
Anatomically speaking, the prostate consists of five distinct lobes: 1
This gland is also considered to be divided into several different zones, including: 4
Several tubular structures pass through the prostate. These include the proximal urethra and two ejaculatory ducts.
The ejaculatory ducts enter the prostate where it emerges from the seminal vesicles. Both structures come together at a portion of the urethra within the prostate called the “ seminal colliculus .”
Occasionally, doctors find congenital variations in the anatomy of the prostate. That means the gland develops irregular features.
Though relatively uncommon, the median lobe of this gland is sometimes absent. When that happens, the anterior and lateral lobes are directly connected. 4
In addition, some people are born with an extra lobe.
The prostate is shaped like a cone. It sits between the penis and bladder, just in front of the rectum. It has five lobes, three zones, and several tubes that pass through it. Anatomical variations, such as missing or extra lobes, are uncommon but can occur.
The prostate is a supportive organ of the male reproductive system. It serves an essential function in the health and maintenance of sperm.
The primary role of this gland is to secrete an alkaline solution that surrounds sperm. This fluid from the prostate contains an enzyme called “prostate-specific antigen” (PSA). It neutralizes the area immediately surrounding sperm.
The solution protects sperm when it enters the acidic environment of the vagina during sex. This allows sperm to survive a longer amount of time so they can access the egg. Furthermore, fluids from the prostate work to nourish and feed sperm. 5
These functions are essential for the process of conception. PSA plays a vital role in male fertility. That’s because it helps increase the motility of sperm .
Prostate fluid combines with other fluids in the urethra to make up semen . These include: 5
The role of the prostate is to provide fluid to protect sperm. This protective fluid gives sperm extra time to reach the egg during reproduction.
Several major health conditions affect the prostate, including cancer. However, most conditions that affect the prostate are benign (non-cancerous).
One of the most common issues that arise with this gland is benign prostatic hyperplasia (BPH). This condition is especially common in older people. It is characterized by an enlarged prostate.
An enlarged prostate can narrow the urethra or lead to it pressing up against the bladder. This can cause symptoms such as:
Treatment approaches tend to be conservative. They may include:
Especially in the initial presentation , this condition can mimic BPH. However, with prostate cancer, you might experience lower back pain, as well. Like other cancers, prostate cancer can spread to other organs.
Risk factors for developing prostate cancer include: 7
The most commonly used measure to correlate weight and height is the body mass index (BMI). It uses weight and height to try and estimate body fat. The resulting number is then used to categorize people as underweight, normal weight, overweight, obese, or morbidly obese. BMI is not perfect, however, and does not account for other factors that determine body composition like age, muscle mass, or sex. BMI calculations may, for example, overestimate body fat in athletes or in older people. Additionally, BMI can also stigmatize and shame people who do not meet what is considered an ideal weight or body shape. 8
People over age 55 are more likely to develop prostate cancer, but more often, it occurs even later. In fact, 60% of prostate cancers occur in people over age 65.
There is a wide range of treatment options for this condition. These include: 9
Bacterial infection of the prostate is called prostatitis. This condition can lead to pain in the prostate.
This disease can be difficult to diagnose. That’s because the same kind of bacteria can also lead to urinary tract infection (UTI). However, antibiotic treatments are highly effective in solving the problem.
Initial prostate tests may be done by a specialist or primary care provider. A urologist is a doctor that specializes in the urinary tract and male reproductive organs, including the prostate. They can assess the health of the prostate in a variety of ways.
Procedures vary from physical examination to the use of imaging technologies. Here’s a quick breakdown of some of the most common approaches.
The first-line approach to prostate health assessment is the digital rectal examination . Wearing gloves and lubricating their hand, the healthcare provider will ask you to lay over an examination table. They will then insert a finger into the rectum to feel the prostate.
This exam checks for inflammation or any other irregularities in shape. Though uncomfortable, the procedure is brief, and it’s a routine part of health examination for people with a prostate who are 50 and older. 10
The PSA test assesses levels of PSA within the bloodstream. The PSA level rises when a man has prostate cancer, but a number of other factors can affect PSA levels, so routine screening is no longer recommended. Anyone considering PSA testing should discuss possible benefits and harms with their healthcare provider. 11 The U.S. Preventive Services Task Force recommends not screening men 70 years old or older. 12
Your healthcare provider may perform a urine analysis to diagnose prostatitis or the presence of abnormal substances in the prostate. This test can also help differentiate between urethral and prostate infection.
In addition, your provider can assess the overall function of the prostate, urethra, and bladder with urodynamic testing. This test looks at the flow of urine as well as the bladder's storage capacity. 2
Ultrasound involves the use of sound waves to map structures in the abdomen, including the prostate.
A gel is applied to the abdomen during an ultrasound, and a hand-held device called a transducer is moved over the area. Then, specialists examine the images captured to get an overall sense of the health of the organ.
When previous tests have unearthed potential cancer, your doctor may do a biopsy guided by ultrasound. This can confirm the diagnosis.
Using ultrasound imaging as a guide, your doctor will insert a needle into the prostate to collect a tissue sample. A lab technician will then assess the sample for the presence of cancer cells.
Doctors also rely on a variety of imaging techniques used to diagnose prostate issues. These may include:
These approaches can help detect abnormal growths. However, a biopsy is often necessary to confirm cancer.
The prostate is a small organ that sits between the penis and the bladder. Its main function is to coat sperm with a protective liquid to have adequate time to reach the egg during reproduction.
The prostate may become enlarged or infected. Cancer can also affect the prostate. Cancer most often affects people older than 55.
A prostate exam is a routine part of healthcare screening after age 50. If you have symptoms of a problem with your prostate, including frequent urination, weak stream, or low back pain, your healthcare provider may perform other screening tests, as well.
National Institute of Diabetes and Digestive and Kidney Diseases. Prostate tests .
Bhavsar A, Verma S. Anatomic imaging of the prostate . Biomed Res Int . 2014;2014:728539. doi:10.1155/2014/728539
National Cancer Institute. Accessory glands .
Rawla P. Epidemiology of prostate cancer . World J Oncol . 2019;10(2):63-89. doi:10.14740/wjon1191
Gutin I. In BMI We Trust: Reframing the Body Mass Index as a Measure of Health. Soc Theory Health . 2018;16(3):256-271. doi:10.1057/s41285-017-0055-0
US Preventive Services Task Force, Grossman DC, Curry SJ, et al. Screening for prostate cancer: US Preventive Services Task Force recommendation statement . JAMA . 2018;319(18):1901-1913. doi:10.1001/jama.2018.3710
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From Wikipedia, the free encyclopedia
This is the latest accepted revision , reviewed on 3 September 2022 .
Gland of the male reproductive system in most mammals
This article is about the male prostate gland. For the equivalent female prostate gland, see Skene's gland . For the journal, see The Prostate .
Not to be confused with Prostrate (body position) .
A digital rectal examination may be performed to investigate how large a prostate is
A diagram of prostate cancer pressing on the urethra, which can cause symptoms
Micrograph showing normal prostate cancer in the right upper aspect of image. HPS stain . Prostate biopsy .
^ Jump up to: a b c d e f g h i j k l m n o p Young, Barbara; O'Dowd, Geraldine; Woodford, Phillip (2013). Wheater's functional histology: a text and colour atlas (6th ed.). Philadelphia: Elsevier. pp. 347–8. ISBN 9780702047473 .
^ Leissner KH, Tisell LE (1979). "The weight of the human prostate". Scand. J. Urol. Nephrol . 13 (2): 137–42. doi : 10.3109/00365597909181168 . PMID 90380 .
^ Jump up to: a b c d e f g h i j k l m n o p q Standring, Susan, ed. (2016). "Prostate". Gray's anatomy : the anatomical basis of clinical practice (41st ed.). Philadelphia. pp. 1266–1270. ISBN 9780702052309 . OCLC 920806541 .
^ Jump up to: a b c d e f g h Goddard, Jonathan Charles (January 2019). "The history of the prostate, part one: say what you see" . Trends in Urology & Men's Health . 10 (1): 28–30. doi : 10.1002/tre.676 .
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^ Jump up to: a b "Prostate Cancer Information from the Foundation of the Prostate Gland." Prostate Cancer Treatment Guide. Web. 14 June 2010.
^ Cohen RJ, Shannon BA, Phillips M, Moorin RE, Wheeler TM, Garrett KL (2008). "Central zone carcinoma of the prostate gland: a distinct tumor type with poor prognostic features". The Journal of Urology . 179 (5): 1762–7, discussion 1767. doi : 10.1016/j.juro.2008.01.017 . PMID 18343454 .
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