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Introduction: Given the relatively recent growth in access to heroin and a more permissive atmosphere surrounding its use, we hypothesized that an increasing number of persons with limited experience and tolerance to opioids would experiment with heroin as their first opioid rather than more common prescription opioid analgesics. To limit long-term recall and survival bias, analyses was restricted to opioid initiation that occurred in the past ten years Results: In , only 8. The use of commonly prescribed opioids, oxycodone and hydrocodone, dropped from Conclusions: Our data document that, as the most commonly prescribed opioids - hydrocodone and oxycodone - became less accessible due to supply-side interventions, the use of heroin as an initiating opioid has grown at an alarming rate. Given that opioid novices have limited tolerance to opioids, a slight imprecision in dosing inherent in heroin use is likely to be an important factor contributing to the growth in heroin-related over dose fatalities in recent years. Abstract Introduction: Given the relatively recent growth in access to heroin and a more permissive atmosphere surrounding its use, we hypothesized that an increasing number of persons with limited experience and tolerance to opioids would experiment with heroin as their first opioid rather than more common prescription opioid analgesics. Publication types Research Support, Non-U. Substances Analgesics, Opioid Heroin.

Increased use of heroin as an initiating opioid of abuse

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Port Louis buy Heroin