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MDMA 3,4-methylenedioxymethamphetamine , was first developed in the early s in Germany as a parent compound to be used to synthesize other pharmaceuticals. It was patented in by a drug company called Merck, and at first, scientists originally thought it could be used as an appetite suppressant. In late the FDA approved the first small clinical trial for MDMA in psychotherapy and it was determined to aid in recovery from post traumatic stress disorder. It is also known for having psychedelic effects similar to mescaline. MDMA works by increasing the activity of three neurotransmitters the chemical messengers of brain cells: Serotonin is responsible for controlling feeling of pain, our moods, and our sexual desires. When the extra serotonin is released by MDMA, it causes mood-elevating effects in its users, such as euphoria, alertness, intensified sense of touch as well as feelings of love, sexual arousal and trust. Users typically report feeling heightened senses of emotional closeness as well as empathy. MDMA is typically taken in the form of a pill or capsule, which are sometimes different colors, and have cartoonish images on them. The effects generally begin 15 minutes after ingestion, and last anywhere from 3 to 6 hours. It is not uncommon for users to take several subsequent doses of MDMA once the effects of the first dose begin to wane. Long term abuse of MDMA can lead to permanent damage to the kidneys, and also increase the risk of heart attack, stroke and high blood pressure. Adverse changes to neuroplasticity and white matter in the brain, also occur when humans use low doses of MDMA. Damage can also be done to the teeth and gums of those who abuse the substance, as oftentimes it can cause the user to grind teeth — which can lead to cavities and gum disease. Studies are also being done with MDMA in relation to enhancing the quality of life in autistic adults with social anxiety as well. Possession of MDMA is illegal in most countries, but limited exceptions exist for scientific and medical research. In it was reported that between 9 and 28 million people used ecstasy 0. About MDMA. EntheoNation — the process of awakening the Divine within. Entheo Nation — a global tribe of visionary people living life at the cutting edge of awakening. Our vision is an environmentally sustainable, socially-just, spiritually-fulfilling, and evolved human presence on this planet, one that integrates ancient wisdom, with modern times. Also, what dosage represents a harmful dose? The discussion of brain lesions is often not how it is discussed by members of the scientific community. That same study also suggests that the brain may recover from serotonergic damage but the amount of bounce back is unknown. The main success of that study on a single baboon was that it showed that a PET analysis mostly agreed with the analysis that was revealed after sacrificing the animal and performing an autopsy. After this information was made public, a study was performed on human subjects by McCann in with the knowledge that PET analysis could be mostly relied upon. Positron emission tomographic evidence of toxic effect of MDMA. The study compared 14 heavy MDMA users with 14 control subjects. They used sophisticated PET scans to try to measure the amount of serotonin axons in each subject. It found that heavy MDMA users mg average dosage between 70 and times tended to have somewhat lower serotonin axon counts. No behavioral or functional impairment was found in these users. George A. That paper and three other connected papers were later retracted by the editor when it was found that the researcher used methamphetamine instead of MDMA, causing many research professionals to call into question the research done throughout his entire career. He claims that the medication was mislabeled by the supplier but the supplier denies this. In any case the results were not at all in line with previous research and that should have been immediately apparent to him after reviewing the test results. To this day he enjoys a prestigious career where he is well funded by government money. About the author, Entheonation EntheoNation — the process of awakening the Divine within. Leave a comment.
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