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Mephedrone

Save my name, email, and website in this browser for the next time I comment. Remember me Log in. Lost your password? Rated 5. Mephedrone , also known as 4- methyl methcathinone 4-MMC or 4- methyl ephedrone , is a synthetic stimulant drug of the amphetamine and cathinone classes. Description Additional information Reviews 1 Mephedrone , also known as 4- methyl methcathinone 4-MMC or 4- methyl ephedrone , is a synthetic stimulant drug of the amphetamine and cathinone classes. It is chemically similar to the cathinone compounds found in the khat plant of eastern Africa. Mephedrone may comes in the form of tablets or a powder, which users can swallow, snort or inject, producing similar effects to MDMA , amphetamines and cocaine. In addition to its stimulant effects, mephedrone produces side effects , of which bruxism is the most common. The metabolism of mephedrone has been studied in rats and humans and the metabolites can be detected in urine after usage. By , 4-MMC was reported to be available for sale on the internet, by law enforcement agencies had become aware of the compound, and by , it had been reported in most of Europe, becoming particularly prevalent in the United Kingdom. How to Order 4-MMC Online Users have reported that 4-MMC causes euphoria , stimulation , an enhanced appreciation for music , an elevated mood , decreased hostility , improved mental function and mild sexual stimulation ; these effects are similar to the effects of cocaine , amphetamines and MDMA , and last different amounts of time depending on the way the drug is taken. Of 70 Dutch users of mephedrone, 58 described it as an overall pleasant experience and 12 described it as an unpleasant experience. In a survey of UK users who had previously taken cocaine, most users found it produced a better-quality and longer-lasting high and was less addictive. It is a chiral compound and both of its enantiomers display similar potency as substrates at dopamine transporters. R -Mephedrone is much less potent than 4-MMC as a substrate at serotonin transporters. The keto oxygen renders 4-MMC more hydrophilic than the corresponding methylamphetamines , which may account for the higher doses required to achieve a similar effect, because meph is less able to cross the blood—brain barrier. A study in mice investigated the interrelation between these two substances , focusing on the psychostimulant and rewarding properties of mephedrone. It found that at low non-stimulant doses alcohol significantly enhanced the psychostimulant effects of mephedrone. This effect was mediated by an increase in synaptic dopamine , as haloperidol , but not ketanserin , was able to block the potentiation by alcohol. Similarly, the rewarding properties of mephedrone were enhanced by a low non-rewarding dose of alcohol. Quantity 5 g, 10 g, 25 g, 50 g, g, g, g. Rated 5 out of 5. Related products. Quick View. Select options. Search for:. Powered by Joinchat. How can we help? Choose an option 5 g 10 g 25 g 50 g g g g Clear.

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