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If you miss a dose of Femalefil and you still intend to engage in sexual activity, take it as soon as you remember. The persistence of CGMP leads to a more prolonged engorgement of the vaginal flush with blood. It relaxes muscles and increases blood flow to particular areas of the body. Check with your doctor before you eat grapefruit or drink grapefruit juice while you are taking Femalefil. Femalefil is a phosphodiesterase enzyme (PDE5) inhibitor.It is the cGMP that is primarily responsible for increasing and decreasing the size of the blood vessels carrying blood to and from the vagina, respectively, and causing the flush. Sexual stimulation that leads to a vaginal flush causes the production and release of nitric oxide in the vagina. Femalefil may work for up to 48 hours after you take it.Take Femalefil by mouth with or without food at least 45 minutes before sexual activity, as directed by your doctor. When the cGMP is destroyed by another enzyme, phosphodiesterase-5, the blood vessels return to their normal size, blood leaves the vaginal area, and the flush ends. Femalefil prevents phosphodiesterase-5 from destroying cGMP so that cGMP stays around longer. This enzyme is responsible for the degradation of cyclic guanosine monophosphate (Cgmp) produced in reaction to sexual stimulation. Continue to take it as directed by your doctor. The more Cgmpis available Femalefil inhibits the PDE5 enzyme, preserving Cgmp levels, therefore aiding sexual viability and durability Filling occurs because the blood vessels that bring blood to the vagina and deliver more blood to vagina, and, at the same time, the blood vessels that take blood away from the vagina remove less blood from the vagina.Side effects are headache; stomach ache; dizziness; flushing (warmth, redness, or tingly feeling); cold symptoms such as runny or stuffy nose, sore throat; nasal congestion; back pain. Texas, New Mexico, Texas, Maryland, NH, IN, Oklahoma, VA, Chicago, Illinois, Memphis, AK, Illinois, El Paso, VT, MT, San Antonio, Washington, TN, Florida, DE, MA, MN, California, Long Beach, WV, MS, KS, ME, Nevada, San Francisco, Missouri, Massachusetts, Ohio, Colorado, Las Vegas, Washington, Minnesota, WI, New Jersey, OR, MO, Virginia Beach, UT, Arizona, Massachusetts, ID, West Virginia, New York, Seattle, Colorado Springs. Arizona, Phoenix, Idaho, Tennessee, Nashville-Davidson, Montana, Hempstead, IA, Alaska, North Carolina, South Carolina, New Hampshire, Miami, Iowa, CA, Mississippi, Baltimore, AR, Indiana, New York, Minneapolis, LA, Wisconsin, Denver, Michigan, North Dakota, North Carolina, NV, OH, AL, Hawaii, Nebraska, HI, Arkansas, Indianapolis, Detroit, NM, Tennessee, KY, NY, Austin, Oklahoma, South Dakota, Albuquerque, Rhode Island, Charlotte, Ohio, FL, Nebraska, Missouri, Delaware, Fort Worth, District of Columbia, New Orleans, Pennsylvania, GA, San Diego, NY, Minnesota, Colorado, Omaha, Tulsa, ND, WA, New Mexico, Washington, Boston, NE, Connecticut, Pennsylvania, Vermont, Tucson, OK, Oregon, Kansas, Virginia, MI, Nevada, Cleveland, CT, Honolulu, NC, Kansas City, Dallas, Utah, Fresno, Louisiana, Maryland, Hawaii, Oregon, Los Angeles, Oakland, Oklahoma City, Georgia, California, PA, Houston, Wyoming, MD, Louisiana, Virginia, IL, Jacksonville, WYNJ, Indiana, Sacramento, Alabama, AZ, Mesa, SC, Portland, Milwaukee, Columbus, TX, CO, SD, Georgia, Philadelphia, Atlanta, Kentucky, DC, San Jose, Brookhaven, Wisconsin, Maine, RI, Michigan, Florida, District of Columbia,