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National Institute of Population Studies (NIPS)
NIPS is a premier research organization established by the Government of Pakistan since 1986 and currently, it is working under umbrella of the Ministry of National Health Services, Regulations & Coordination (NHSR&C). The NIPS has been mandated to act as a technical arm of the Government for undertaking high quality research and to produce evidence-based data, information for utilization by the Public sector and others agencies for policy formulation, strategic planning and making reference in the spheres of demography, population & development and health.
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core functions of NIPS
Research Brief & Newsletter (No. 9, January 2014)
Newsletter
Pakistan Maternal Mortality Survey (PMMS) 2019 - L...
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Pakistan Maternal Mortality Survey (PMMS) 2019 Pol...
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WHO
Population Council
Carry forward substantive and methodological research in the areas of population dynamics
Conduct academic, operational research in the field of population and health.
Carry forward substantive and methodological research in the areas of population dynamics
Conduct academic, operational research in the field of population and health.
Recognizing that each human being deserves respect and value ...
The research is designed and undertaken in the manners ....
NIPS undertakes research for doing good to the society .....
NIPS is a premier research organization established by the Government of Pakistan since 1986 and currently, it is working under umbrella of the Ministry of National Health Services, Regulations & Coordination (NHSR&C)
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Non-Invasive Prenatal Screening (NIPS)
Also Known As:
NIPS
Non-Invasive Prenatal Testing
NIPT
Cell-Free Fetal DNA
cffDNA
cfDNA
Formal Name:
Cell-Free DNA Prenatal Screen for Fetal Aneuploidy
Tests
First Trimester Screening
Amniocentesis
Chromosome Analysis (Karyotyping)
Maternal Serum Screening, Second Trimester
National Society of Genetic Counselors: Before and During Pregnancy
National Human Genome Research Institute: Chromosome Abnormalities
NIH Genetic and Rare Diseases Information Center: Chromosome Disorders
National Association for Down Syndrome
National Down Syndrome Society
Trisomy 18 Foundation
MedlinePlus Medical Encyclopedia: Trisomy 13
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For pregnant women, to assess the risk of your developing baby (fetus) having certain chromosome disorders
During or after the 10 th week of pregnancy
A blood sample drawn from a vein in the mother’s arm
Non-invasive prenatal screening (NIPS) helps determine the risk that a pregnant woman’s developing baby (fetus) has a chromosome disorder. It is not a diagnostic test, meaning it cannot tell for certain whether your baby is affected or unaffected. If NIPS shows an increased risk for a specific chromosome disorder, diagnostic testing by chorionic villus sampling (CVS) or amniocentesis is recommended to establish the true diagnosis.
NIPS evaluates a type of genetic material called cell-free DNA (cfDNA) that is released by cells from the placenta and circulates in the mother’s blood during pregnancy. The cfDNA from the placenta generally reflects the genetic makeup of the developing baby (fetus). NIPS detects chromosome disorders in placental cfDNA and can be performed as early as the 10th week of pregnancy.
Although there are many similarities among various versions of NIPS, laboratories may offer opt-in or opt-out choices for things like the sex chromosomes or microdeletions. It is important to speak to your healthcare practitioner about which test is being recommended for you. NIPS may screen for:
Non-invasive prenatal screening (NIPS) may be used to assess the risk of a pregnant woman’s developing baby (fetus) having a chromosome disorder, such as Down syndrome (trisomy 21), Edwards syndrome (trisomy 18), or Patau syndrome (trisomy 13). It may also be used to identify sex chromosome abnormalities (changes to the number of X or Y chromosomes present). Some laboratories offer additional testing for conditions caused by small segments of missing information on specific chromosomes, called microdeletion syndromes.
You should discuss this and other screening options with your health care practitioner to ensure it is the best choice for you. If you are not certain which prenatal screening or diagnostic test is right for you, it may be a good idea to speak with a genetic counselor.
The non-invasive prenatal screening (NIPS) can be offered during or after the tenth week of pregnancy. Samples collected prior to this time are automatically rejected, so it is important to be certain that the pregnancy is at a minimum of 10 weeks along.
Results may be reported as “low risk” (negative) or “high risk” (positive).
A NIPS result that is reported as “negative” or as “low risk” means that it is unlikely the baby has any of the specific chromosome disorders that were screened. Most NIPS tests evaluate the risk for Down syndrome (trisomy 21), Edwards syndrome (trisomy 18) and Patau syndrome (trisomy 13), but depending on how your healthcare practitioner ordered the test, it may also include the sex chromosomes (X and Y) and certain microdeletion syndromes.
It is important to remember that NIPS is a screening test, not a diagnostic test, so it is possible that the baby actually has a chromosomal disorder, even though the screening results show lo
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