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The suspension is light yellow in color, with a banana smell; during storage, a precipitate may form, after shaking it returns to the state of a homogeneous suspension. After oral administration, it is practically not absorbed from the digestive tract, creating a high concentration of the active substance in the intestine. Due to these pharmacokinetic features, the drug has an exclusively enteric antiseptic effect, does not have systemic antibacterial activity, does not cause General toxic effects; it is excreted from the body with feces. The drug does not affect the clinical and biochemical parameters of the blood test. Nifuroxazide — intestinal antiseptic, derivative of 5-nitrofuran; active against most pathogens of intestinal infections including strains, mutants resistant to other antimicrobial drugs : gram a family of Staphylococcus and gram-negative family Enterobacteriaceae: Escherichia, Citrobacter, Enterobacter, Klebsiella, Salmonella, Shigella, Proteus, Yersinia , and Vibrio cholerae. It is not active against bacteria of the genus Pseudomonas and the genus Proteus the species Proteus inconstans , as well as strains of the subgroup a of the species Providentia alcalifaciens. It is assumed that the drug inhibits the activity of dehydrogenases and disrupts the synthesis of proteins in pathogenic bacteria. In average therapeutic doses, it has bacteriostatic activity, and in higher doses it acts bactericidal. The effect is evident from the first hours of treatment. In therapeutic doses, it practically does not disturb the balance of the symbiotic bacterial flora of the intestine; it does not cause the development of resistant strains of pathogenic microorganisms and cross-resistance of bacteria to other antimicrobial agents, which allows, if necessary, for generalized infections, it can be prescribed in combination therapy with systemic drugs. In intestinal infections of viral origin, it prevents the development of bacterial superinfection. Acute and chronic diarrhea caused by intestinal gram-positive bacteria Staphylococcus spp. There is no data on the adverse effect on the fetus when using the drug during pregnancy. If necessary, with caution, the drug can be prescribed to pregnant and breast-feeding women. Before use, shake the bottle thoroughly to obtain a homogeneous suspension. Doses for children from 2 to 6 months — measuring spoons per 2. The drug is recommended to be taken at regular intervals, regardless of food intake. The course of treatment is days. TopGear is well tolerated, practically does not show any side effects, only rarely may occur temporary abdominal pain, nausea, increased diarrhea. These symptoms do not require discontinuation of the drug. In rare cases, there may be shortness of breath, skin rashes, itching, which do not require the withdrawal of the drug. During treatment with nifuroxazide should avoid simultaneous use of oral means because of the strong adsorption properties of the drug. Since nifuroxazide does not enter the circulatory system, interaction with systemic drugs is unlikely and is still unknown. The symptoms of overdose are not described. In case of overdose, gastric lavage and symptomatic treatment are recommended. The drug is not prescribed as a monotherapy for the treatment of intestinal infections complicated by septicemia. If there are symptoms of dehydration, rehydration therapy should be performed in conjunction with treatment for adults, about 2 liters of fluid per day. During treatment, you should follow a certain diet: do not eat raw fruits and vegetables, juices, spicy and fatty foods. Before prescribing the suspension to infants, it is necessary to exclude their congenital deficiency of enzymes that break down sucrose. Effect of the drug on the ability to drive vehicles and maintain moving mechanisms: nifuroxazid does not affect the ability to drive vehicles and work with mechanisms. Poniatowski, 5, Poland. Send consumer complaints to the address: Moscow representative office of Gedeon Richter, , Moscow, 4th Dobryninsky lane, 8. Information about prescription drugs is for professionals only. The information provided should not be used by patients to make an independent decision on the use of the presented drugs and cannot serve as a substitute for a full-time consultation with a doctor. A description of the active substances of the drug is provided. The scientific information provided is generalized and cannot be used to decide on the possibility of using a specific drug. The appearance of the product may differ from the photos on the site. Рецептурный препарат. Product is available in pharmacies:. Add to cart. All products in the order are reserved for 24 hours, after that the order is automatically canceled. Brief information General description Manufacturer: Гедеон Рихтер Active substance Нифуроксазид There are contraindications, specialist advice is required The appearance of the product may differ from the photos on the site. Composition Suspension for the reception inside 5 ml active substance: nifuroxazide mg excipients: carbomer mg; sucrose mg; sodium hydroxide Pharmacokinetics After oral administration, it is practically not absorbed from the digestive tract, creating a high concentration of the active substance in the intestine. Pharmacodynamics Nifuroxazide — intestinal antiseptic, derivative of 5-nitrofuran; active against most pathogens of intestinal infections including strains, mutants resistant to other antimicrobial drugs : gram a family of Staphylococcus and gram-negative family Enterobacteriaceae: Escherichia, Citrobacter, Enterobacter, Klebsiella, Salmonella, Shigella, Proteus, Yersinia , and Vibrio cholerae. Indications of the drug Acute and chronic diarrhea caused by intestinal gram-positive bacteria Staphylococcus spp. Contraindications hypersensitivity to any of the components of the drug; Allergy to 5-nitrofuran derivatives; children up to 2 months old; prematurity. Use during pregnancy and lactation There is no data on the adverse effect on the fetus when using the drug during pregnancy. Dosage and administration Inside. Doses for adults — 1 scoop per 5 ml 4 times a day. Side effect TopGear is well tolerated, practically does not show any side effects, only rarely may occur temporary abdominal pain, nausea, increased diarrhea. Interaction During treatment with nifuroxazide should avoid simultaneous use of oral means because of the strong adsorption properties of the drug. Overdose The symptoms of overdose are not described. Conditions of supply of pharmacies By prescription. Manufacturer Gideon Richter Romania A. Owner of the registration certificate: Gedeon Richter, Budapest, Hungary. Производитель Гедеон Рихтер. This product is in 7 pharmacies, see all 9 Sh. Экофурил мг капс N Available in another region. Нифурал мг капс N КонтрДиар мг капс N The goods are available in pharmacies:. This product is in 8 pharmacies, see all 1 Kantemirova Street, Ajbolit 9 Sh. Ignatievskoe , Tvoyaapteka 17 pom Sh. Town Pharmacy Catalog Basket 0. All pharmacies 1 Kantemirova Street Ajbolit с 8. Chigiri Social pharmacy с 8. Novotroitskoe Perekrestok pharmacy с 9. Ignatievskoe Tvoyaapteka с 8. Ignatievskoe Social pharmacy с 8.

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