Ncov Cock Li

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Affiliation
1 National Clinical Research Centre for Metabolic Diseases, State Key Laboratory of Medical Genomics, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, 200025 Shanghai, China.
Yanan Cao et al. Cell Discov. 2020.
Affiliation
1 National Clinical Research Centre for Metabolic Diseases, State Key Laboratory of Medical Genomics, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, 200025 Shanghai, China.
Keywords: Bioinformatics; Genomic analysis.
Conflict of interestThe authors declare that they have no conflict of interest.
Fig. 1. The coding-region variants and eQTL…
Fig. 1. The coding-region variants and eQTL variants for ACE2 in East Asian and other…
a Schematics of 32 coding variants in ACE2 identified in the ChinaMAP and 1KGP databases. Yellow stars indicate the nonsense variants; dots indicate the missense variants. The number of samples with hotspot variants was marked. b The distribution of hotspot missense mutations of ACE2 in different populations. The colors indicate different populations. c The distribution and the allele frequencies of representative eQTL variants for ACE2 in different populations. Pie charts depict the allele frequencies of an intron variant of ACE2 (rs4646127) in the world. Orange color denotes the frequency of alteration allele, and blue color denotes the reference allele. The allele frequencies of 15 eQTLs for ACE2 gene are shown in tables. The color gradient from blue to red indicates the increasing of allele frequencies. The allele frequencies of INDEL variant rs200781818 were annotated by the gnomAD database. EAS, East Asian; EUR, European; AFR, African; SAS, South Asian; AMR, Ad Mixed American.
Wan Y, Shang J, Graham R, Baric RS, Li F. Wan Y, et al. J Virol. 2020 Mar 17;94(7):e00127-20. doi: 10.1128/JVI.00127-20. Print 2020 Mar 17. J Virol. 2020. PMID: 31996437 Free PMC article.
Tian X, Li C, Huang A, Xia S, Lu S, Shi Z, Lu L, Jiang S, Yang Z, Wu Y, Ying T. Tian X, et al. Emerg Microbes Infect. 2020 Feb 17;9(1):382-385. doi: 10.1080/22221751.2020.1729069. eCollection 2020. Emerg Microbes Infect. 2020. PMID: 32065055 Free PMC article.
Zhuang MW, Cheng Y, Zhang J, Jiang XM, Wang L, Deng J, Wang PH. Zhuang MW, et al. J Med Virol. 2020 Nov;92(11):2693-2701. doi: 10.1002/jmv.26139. Epub 2020 Jul 2. J Med Virol. 2020. PMID: 32497323 Free PMC article.
Wu J, Deng W, Li S, Yang X. Wu J, et al. Cell Mol Life Sci. 2021 Jan;78(2):531-544. doi: 10.1007/s00018-020-03611-x. Epub 2020 Aug 11. Cell Mol Life Sci. 2021. PMID: 32780149 Free PMC article. Review.
Khan T, Agnihotri K, Tripathi A, Mukherjee S, Agnihotri N, Gupta G. Khan T, et al. Altern Ther Health Med. 2020 Aug;26(S2):56-64. Altern Ther Health Med. 2020. PMID: 32412918 Review.
Taher I, Almaeen A, Ghazy A, Abu-Farha M, Mohamed Channanath A, Elsa John S, Hebbar P, Arefanian H, Abubaker J, Al-Mulla F, Alphonse Thanaraj T. Taher I, et al. Saudi J Biol Sci. 2021 Jul 17. doi: 10.1016/j.sjbs.2021.07.037. Online ahead of print. Saudi J Biol Sci. 2021. PMID: 34305429 Free PMC article. Review.
Farhud DD, Zokaei S. Farhud DD, et al. Iran J Public Health. 2020 Oct;49(Suppl 1):1-3. doi: 10.18502/ijph.v49iS1.3663. Iran J Public Health. 2020. PMID: 34268199 Free PMC article. No abstract available.
Pisaturo M, Calò F, Russo A, Camaioni C, Giaccone A, Pinchera B, Gentile I, Simeone F, Iodice A, Maggi P, Coppola N. Pisaturo M, et al. Front Aging Neurosci. 2021 Jun 29;13:698184. doi: 10.3389/fnagi.2021.698184. eCollection 2021. Front Aging Neurosci. 2021. PMID: 34267649 Free PMC article.
Zhang C, Verma A, Feng Y, Melo MCR, McQuillan M, Hansen M, Lucas A, Park J, Ranciaro A, Thompson S, Rubel MA, Campbell MC, Beggs W, Hirbo J, Mpoloka SW, Mokone GG, Center RG, Nyambo T, Meskel DW, Belay G, Fokunang C, Njamnshi AK, Omar SA, Williams SM, Rader D, Ritchie MD, de la Fuente Nunez C, Sirugo G, Tishkoff S. Zhang C, et al. medRxiv. 2021 Jul 1:2021.06.28.21259529. doi: 10.1101/2021.06.28.21259529. Preprint. medRxiv. 2021. PMID: 34230933 Free PMC article.
Patel KHK, Li X, Quint JK, Ware JS, Peters NS, Ng FS. Patel KHK, et al. BMC Endocr Disord. 2021 Jul 3;21(1):144. doi: 10.1186/s12902-021-00805-7. BMC Endocr Disord. 2021. PMID: 34217276 Free PMC article.

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