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Methamphetamine increases levels of the neurotransmitters dopamine , norepinephrine, and serotonin which stimulates brain cells, enhancing mood altering levels of energy, alertness and other bodily functions. Also Known As: Some common street names for methamphetamine include meth, crystal, speed, crank, and tweak. Drug Class: Meth is a stimulant drug that increases activity in the central nervous system. Common Side Effects: Meth use can lead to side effects such as nausea, diarrhea, vomiting, seizures, anxiety, and depression. Methamphetamine most often takes the form of a white, crystalline powder. While it is odorless, it has a bitter taste. The powder dissolves easily in water. Crystal meth looks like chips of clear ice. Illegal forms of the drug can be snorted, smoked, injected, or orally ingested. When methamphetamine is injected or smoked, it immediately produces an intensely pleasurable sensation known as a 'rush' or a 'flash. Snorting methamphetamine produces a euphoric sensation , but not a rush. The effects of methamphetamine are similar to those of other stimulants and include feelings of pleasure, agitation, increased sociability, physical alertness, decreased appetite, low inhibitions, and mental confusion. Even when taken in small amounts, methamphetamine can cause increased wakefulness and physical activity. A decreased appetite is also common. Research published in found that methamphetamine has neurotoxic effects, leading to damage to the serotonin and dopamine receptors in the brain. The long-term use of methamphetamine can cause damage to the brain similar to other conditions that injure the brain. This brain damage lingers for months even after use has stopped. The neurological effects of meth use can be permanent, even after a person quits. Methamphetamine misuse can also produce extreme anorexia. Even over a short period of use, methamphetamine can cause drastic changes in physical appearance. While approved, the FDA cautions that there is a high potential for dependence and its therapeutic benefits tend to be quite limited. Methamphetamine is occasionally used off-label in the treatment of sleep disorders such as idiopathic hypersomnia and narcolepsy. It can cause hyperthermia and an irregular heartbeat. There is also the potential for cardiovascular collapse. Other effects of meth use on the central nervous system can produce symptoms like irritability, confusion, anxiety, paranoia, and aggressiveness. Some users also suffer from prolonged insomnia and tremors. Hyperthermia and convulsions can be fatal. Methamphetamine can also cause irreversible damage to the blood vessels in the brain, which can result in a stroke. Overdose is another danger associated with methamphetamine use. An overdose results in a rapid onset of physiological deterioration, eventually leading to a heart attack or stroke. Because of the speed of onset, death occurs suddenly and unexpectedly. A meth overdose produces profuse sweating, rapid breathing, increased heart rate, and dilated pupils. A person who has overdosed on meth will have a high temperature, kidney failure, and cardiovascular collapse. If you suspect that someone has overdosed on methamphetamine, contact emergency services immediately. As a result of anti-drug campaigns and popular media, many people have a mental picture of what they think a meth user looks like. Pictures of people who have misused meth and have undergone shocking physical changes are graphic and can make for a convincing argument against drug use, but they paint a very narrow picture of who uses meth. In reality, approximately 1. Methamphetamine has a high risk of tolerance and dependence. Tolerance to methamphetamine develops quickly. How long meth stays in your system depends upon a variety of factors including metabolism, body mass, and the frequency of use. It can usually be detected by blood test for one to three days, by urine test for up to a week, and by hair follicle test for up to 90 days. Methamphetamine is highly addictive and users become physically dependent upon the drug quickly. Users will seek and use more methamphetamine in order to get back to that state of pleasure or to just feel 'normal' again. This results in physical dependence on the drug and is a never-ending cycle for the majority of users until serious treatment is sought. Once you have decided to quit, detoxification is the first step. This process begins once you stop taking methamphetamine and continues until your system is free of it and has adjusted to being off the drug. Initial withdrawal symptoms usually begin within 24 hours of the last dose, peak after about 10 days, and may last three weeks or more. People often go through the detox and withdrawal process at home, but residential and outpatient treatment options are also available. If you decide to go through the process at home, make sure to inform your doctor and have a friend or loved one check in on you often. The withdrawal from a drug like meth is not easy and is filled with days or weeks of many symptoms. People who stop using methamphetamine experience irritability, depression, fearfulness, and loss of energy. Possibly the hardest withdrawal symptom to overcome, however, is the extreme craving for the drug. People withdrawing from methamphetamine can alternate from wanting to sleep all the time to not being able to sleep. Withdrawal symptoms can last for several weeks. If you or a loved one is ready to quit using methamphetamine, there are resources available that can help. You can start by talking to your doctor who can then assess your current physical health, talk to you about the next steps, and refer you to treatment centers in your area. Long-term treatments typically utilize behavioral therapy approaches including contingency management CM and cognitive-behavioral therapy CBT. There are a few medications that may be useful in the treatment of some patients with methamphetamine use such as naltrexone, modafinil, or bupropion. There is research ongoing around the potential use of anti-methamphetamine monoclonal antibodies. Other approaches that may be used include individual counseling, drug testing, support groups, and step programs. For more mental health resources, see our National Helpline Database. Learn the best ways to manage stress and negativity in your life. National Institute on Drug Abuse. Updated April Neurotoxicity of methamphetamine and 3,4-methylenedioxymethamphetamine. Life Sci. Drug Alcohol Depend. Food and Drug Administration. Updated March Turner M. J Clin Sleep Med. Acute methamphetamine intoxication: brain hyperthermia, blood-brain barrier, brain edema, and morphological cell abnormalities. Int Rev Neurobiol. Library of Medicine. Updated January 14, What is the scope of methamphetamine misuse in the United States? What is methamphetamine? Updated May Verstraete AG. Detection times of drugs of abuse in blood, urine, and oral fluid. Ther Drug Monit. Characterizing methamphetamine withdrawal in recently abstinent methamphetamine users: a pilot field study. Am J Drug Alcohol Abuse. Pharmacological approaches to methamphetamine dependence: a focused review. Br J Clin Pharmacol. More in Addiction. How to Recognize Methamphetamine Methamphetamine most often takes the form of a white, crystalline powder. Brain Recovery After Meth Use. Presence of drug paraphernalia Hyperactivity Dilated pupils Poor appetite Sudden weight loss Burns on lips and fingers Jerky movements and twitching Skin sores and scabs Changes in sleep patterns Rotten teeth. What to Expect From Meth Withdrawal. Contingency management allows people to earn vouchers for desired rewards in exchange for staying drug-free. Cognitive-behavioral therapy works to change harmful thought patterns and behaviors that contribute to drug use. This approach also teaches people new coping skills and strategies that can help them abstain from drug use in the future. Common Questions About Methamphetamine. Was this page helpful? Thanks for your feedback! Sign Up. What are your concerns? Article Sources. Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Related Articles. How Methamphetamine Takes a Toll on the Body. Health Effects of Illegal Drugs. Information About Commonly Abused Drugs. Long-Term Effects of Methamphetamine Abuse. Verywell Mind uses cookies to provide you with a great user experience. By using Verywell Mind, you accept our.

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Get the latest information from CDC Coronavirus. Methamphetamine is a powerful, highly addictive stimulant that affects the central nervous system. Crystal methamphetamine is a form of the drug that looks like glass fragments or shiny, bluish-white rocks. It is chemically similar to amphetamine, a drug used to treat attention-deficit hyperactivity disorder ADHD and narcolepsy, a sleep disorder. Other common names for methamphetamine include blue, crystal, ice, meth, and speed. Because the 'high' from the drug both starts and fades quickly, people often take repeated doses in a 'binge and crash' pattern. In some cases, people take methamphetamine in a form of binging known as a 'run,' giving up food and sleep while continuing to take the drug every few hours for up to several days. Methamphetamine increases the amount of the natural chemical dopamine in the brain. Dopamine is involved in body movement, motivation, and reinforcement of rewarding behaviors. Taking even small amounts of methamphetamine can result in many of the same health effects as those of other stimulants, such as cocaine or amphetamines. These include:. Currently, most methamphetamine in the United States is produced by transactional criminal organizations TCOs in Mexico. This methamphetamine is highly pure, potent, and low in price. The drug can be easily made in small clandestine laboratories, with relatively inexpensive over-the-counter ingredients such as pseudoephedrine, a common ingredient in cold medications. To curb this kind of production, the law requires pharmacies and other retail stores to keep a purchase record of products containing pseudoephedrine, and take steps to limit sales. Methamphetamine production also involves a number of other very dangerous chemicals. Toxic effects from these chemicals can remain in the environment long after the lab has been shut down, causing a wide range of health problems for people living in the area. These chemicals can also result in deadly lab explosions and house fires. People who inject methamphetamine are at increased risk of contracting infectious diseases such as HIV and hepatitis B and C. These diseases are transmitted through contact with blood or other bodily fluids that can remain on drug equipment. Methamphetamine use can also alter judgment and decision-making leading to risky behaviors, such as unprotected sex, which also increases risk for infection. In studies of people who used methamphetamine over the long term, severe changes also affected areas of the brain involved with emotion and memory. Although some of these brain changes may reverse after being off the drug for a year or more, other changes may not recover even after a long period of time. What they do know is that people can test positive for methamphetamine after exposure to secondhand smoke. Yes, a person can overdose on methamphetamine. An overdose occurs when the person uses too much of a drug and has a toxic reaction that results in serious, harmful symptoms or death. In , about 15 percent of all drug overdose deaths involved the methamphetamine category, and 50 percent of those deaths also involved an opioid, with half of those cases related to the synthetic opioid fentanyl. It is important to note that cheap, dangerous synthetic opioids are sometimes added to street methamphetamine without the user knowing. Because methamphetamine overdose often leads to a stroke, heart attack, or organ problems, first responders and emergency room doctors try to treat the overdose by treating these conditions, with the intent of:. Yes, methamphetamine is highly addictive. When people stop taking it, withdrawal symptoms can include:. While research is underway, there are currently no government-approved medications to treat methamphetamine addiction. The good news is that methamphetamine misuse can be prevented and addiction to the drug can be treated with behavioral therapies. The most effective treatments for methamphetamine addiction so far are behavioral therapies, such as:. Research also continues toward development of medicines and other new treatments for methamphetamine use, including vaccines, and noninvasive stimulation of the brain using magnetic fields. People can and do recover from methamphetamine addiction if they have ready access to effective treatments that address the multitude of medical and personal problems resulting from long-term use. National Institute on Drug Abuse website. May 16, Provides an overview of the latest scientific findings on methamphetamine, including short- and long-term health consequences, effects on pregnancy, and potential prevention and treatment options. Skip to main content. COVID is an emerging, rapidly evolving situation. Revised May What is methamphetamine? Photo by DEA Crystal methamphetamine. How Do Manufacturers Make Methamphetamine? Points to Remember Methamphetamine is usually a white, bitter-tasting powder or a pill. Crystal methamphetamine looks like glass fragments or shiny, bluish-white rocks. Methamphetamine is a stimulant drug that is chemically similar to amphetamine a drug used to treat ADHD and narcolepsy. People can take methamphetamine by smoking, swallowing, snorting, or injecting the drug. Methamphetamine increases the amount of dopamine in the brain, which is involved in movement, motivation, and reinforcement of rewarding behaviors. Short-term health effects include increased wakefulness and physical activity, decreased appetite, and increased blood pressure and body temperature. Long-term health effects include risk of addiction; risk of contracting HIV and hepatitis; severe dental problems 'meth mouth' ; intense itching, leading to skin sores from scratching; violent behavior; and paranoia. Methamphetamine can be highly addictive. When people stop taking it, withdrawal symptoms can include anxiety, fatigue, severe depression, psychosis, and intense drug cravings. A person can overdose on methamphetamine. Because methamphetamine overdose often leads to a stroke, heart attack, or organ problems, first responders and emergency room doctors try to treat the overdose by treating these conditions. The most effective treatments for methamphetamine addiction so far are behavioral therapies. There are currently no government-approved medications to treat methamphetamine addiction. This publication is available for your use and may be reproduced in its entirety without permission from NIDA. Department of Health and Human Services. Cigarettes and Other Tobacco Products. Marijuana as Medicine. Over-the-Counter Medicines. Prescription CNS Depressants. Prescription Opioids. Prescription Stimulants. Synthetic Cathinones 'Bath Salts'. Vaping Devices Electronic Cigarettes. 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