Mommy S Little Helper
⚡ ALL INFORMATION CLICK HERE 👈🏻👈🏻👈🏻
Mommy S Little Helper
Mosaic uses cookies. Read our policy
Share this story
Tweet (opens in a new tab)
Share by email (opens an email client)
Share on Facebook (opens in a new tab)
Share link
Republish
Share this story
Tweet (opens in a new tab)
Share by email (opens an email client)
Share on Facebook (opens in a new tab)
Share link
How did benzodiazepines become the most widely prescribed class of drugs in the world in just a decade?
What a drag it is getting old ‘Kids are different today,’ I hear ev'ry mother say Mother needs something today to calm her down And though she’s not really ill There's a little yellow pill She goes running for the shelter of a mother’s little helper.
So begins the Stones’ 1966 hit ‘Mother’s Little Helper’, a dark and catchy paean to Valium. The words are a social commentary on benzodiazepines, which had just hit the market a few years prior and become wildly popular, particularly among American housewives.
Since the late 1800s, drug manufacturers had been hunting for a new, non-addictive anti-anxiety medication. Previously, patients were given opiates – with predictably disastrous results. Then came barbiturates, which were also written off as too addictive. After that, doctors began prescribing anti-psychotic drugs known as phenothiazines, but those drugs triggered severe side-effects such as uncontrollable facial movements.
In the 1950s, the late Leo Sternbach – a research chemist – began tinkering with an unknown class of compounds: the BZDs, or benzodiazepines. Over several years, he tested some 40 BZDs but all proved ineffective. Finally in 1956, after adding methylamine (a colourless gas derived from ammonia) to one compound, he produced a white powder that made mice sleepy and calm. The Food and Drug Administration approved Librium, the first-ever benzodiazepine, in 1960 and Valium in 1963.
Benzodiazepines latch onto a receptor in the brain, which then activates a neighbouring neurotransmitter known as GABA. GABA release makes people calm and sleepy. The drugs can trigger that GABA rush in minutes, allowing a user to feel calmer almost immediately. Initially, benzodiazepines were hailed as a medical miracle, and they soon became the most widely prescribed class of drugs in the world. Even though the drugs’ addictive properties have now become clear, they remain widely available and are often prescribed for longer than the recommended 2–4 weeks.
Tolerance to the drugs is thought to develop because benzodiazepines weaken the response of receptors in the brain. That means a benzodiazepine user needs to keep ramping up the drug’s dosage to trigger the same calming effect of GABA. The drugs are also non-specific: they act on multiple subunits of GABA, which govern different actions, such as anxiety, restfulness, motor control and cognition. So even if a person goes on the drugs to alleviate social anxiety, they are invariably altering how they think, sleep and even move. That, in turn, explains why a person coming off benzodiazepines may experience wholly new symptoms, such as panic attacks and seizures.
Malcolm Lader, a psychologist and pharmacologist at King’s College London in the UK, began looking at the benzodiazepine craze as a young scientist in the 1970s. He initially assumed that most people on the drugs had ramped up their dose to such a degree that they had become hooked; instead, he found that users had largely remained on the prescribed dosage. “People couldn’t believe that you could still be on your original dose…and still have problems when you try to come off,” he recalls.
In the 1980s, Lader and a team of researchers issued one of the earliest warnings against long-term benzodiazepine use. Since that time, decades of evidence have made clear that taking benzodiazepines comes with serious risks, yet they remain hugely popular. Antidepressants (e.g. Prozac) and cognitive behaviour therapy are effective anxiety treatments, but neither act immediately; antidepressants can also initially worsen symptoms. For many people, benzodiazepines always seem like the better option.
If you could take the high out of drugs, what would be the point in taking them? Sujata Gupta meets the unorthodox doctor who thinks he can block some of the world’s most addictive pills.
Except where otherwise noted, content on this site is free to reuse , and is licensed under a Creative Commons Attribution 4.0 International Licence .
Log in
Create account
Australian owned and operated. Due to our local presence, shipping within Australia will be fast and fully tracked.
The Benefits Are As Multi-fold As Your Child...
Mommy's Tiny Helper - Here To Help Families
Subscribe for the latest updates and product releases!
Home
Shop
How It Works
Blogs
Australian owned and operated. Due to our local presence, shipping within Australia will be fast and fully tracked.
A mobility toy that cleans as your toddler plays
A mobility toy that cleans as your toddler plays
Find out why Mommy's Tiny Helper is the world's new favourite toy.
Improves their mobility and spatial awareness
Enhances their dexterity and tactile faculties
Develops their awareness of object permanence
Learns responsibility and tidiness through play!
Moves smoothly across ALL floor types, including tiles, carpet, concrete, timber, bamboo & linoleum flooring.
Sweeper collects household dirt & debris, including pet hair, and is easy to remove & clean.
High quality construction with thick durable body and stainless steel screws.
Australian designed & owned business.
Mommy's Tiny Helper TM is the world's first ride-on toy fitted with a removable sweeping mechanism! Find out why its loved by both parents and kids!
"Love Mommy's Tiny Helper - it cleans the floor while he's having fun... GENIUS!" - Michelle, stay at home mum
"Kids love it! Picks up dog hair & saves me cleaning! - Brian, Dad
"Amazing! I bought it for my daughter who was starting to walk. She loves it, and it helps her balance while vacuuming the house and having fun!" - Yvette, Mom
"My son loves to help me clean our home, so this was a great gift! Such a cute design." - Lana, Melbourne mum
Be one of the first 100 customers to purchase a Mommy's Tiny Helper and go into the draw to win a $500 Coles/Myer voucher.
All Titles TV Episodes Celebs Companies Keywords Advanced Search
Fully supported English (United States) Partially supported Français (Canada) Français (France) Deutsch (Deutschland) हिंदी (भारत) Italiano (Italia) Português (Brasil) Español (España) Español (México)
I see the reality in this movie. Many won't ever have to deal with the truth of this story but for those have, this is a story that needed to be told. Thank you.
Suggest an edit or add missing content
By what name was Mother's Little Helpers (2019) officially released in Canada in English?
The Best Movies and Series to Watch in October
Hollywood Heartthrobs Through the Years
The millennial children of a groovy 70s burnout come home to do right by a mom who always did them wrong. Based on true lies, it explores the "OK, Boomer" relationship between the free love ... Read all The millennial children of a groovy 70s burnout come home to do right by a mom who always did them wrong. Based on true lies, it explores the "OK, Boomer" relationship between the free love generation and those left to clean up the mess. The millennial children of a groovy 70s burnout come home to do right by a mom who always did them wrong. Based on true lies, it explores the "OK, Boomer" relationship between the free love generation and those left to clean up the mess.
If playback doesn't begin shortly, try restarting your device.
Videos you watch may be added to the TV's watch history and influence TV recommendations. To avoid this, cancel and sign in to YouTube on your computer.
An error occurred while retrieving sharing information. Please try again later.
0:02 / 2:44 • Watch full video Live
Watch ads now so you can enjoy fewer interruptions
Young Korean Girls
Free Panties Porn Videos
Guy Fuck Female Dog