Methylenedioxypyrovalerone

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Methylenedioxypyrovalerone chemical structure Methylenedioxypyrovalerone. Methylenedioxypyrovalerone , also known as MDPV or 1- 3,4-methylenedioxyphenyl pyrrolidinyl-pentanone, is a stimulant drug which acts as a dopamine reuptake inhibitor , reportedly with four times the potency of methylphenidate. It has no history of medical use but has been sold as a 'research chemical' for recreational use. MDPV is not specifically listed as an illegal drug in any country, but its structural similarity to illegal drugs of abuse makes it likely that it would be considered a controlled substance analogue in several countries such as the USA, Australia and New Zealand. Other analogues derived from alpha-pyrrolidinopropiophenone include the 4-methyl analogue pyrovalerone, as well as analogues with no substitution on the aromatic ring, and analogues with between 3 and 6 carbons on the alkyl chain. MDPV is reported to produce long-lasting stimulation. There are anecdotal reports of addiction potential with higher doses. MDPV is the 3,4-methylenedioxy ring-substituted analogue of the appetite supressant pyrovalerone , however despite its apparent structural similarity to the untrained eye, the effects of MDPV bear little resemblance to other methylenedioxyphenylalkylamine derivatives such as MDMA and methylone , instead producing purely dopaminergic stimulant effects with no empathogenic qualities. Doses used vary widely, from as little as 5mg up to hundreds of milligrams in heavy users who have developed significant tolerance to the drugs effects. The drug has been known to be administered intravenously at less than 10mg, which produces a significant stimulation along with reports of insufflation and oral doses exceding 50mg. High doses tend to produce significant and unpleasant side effects especially in novice users, including undesired over-stimulation, dizziness , nausea , anxiety , insomnia , paranoia , loss of appetite and diahorrea. Extended binges on MDPV also produce severe come-down syndrome similar to that of methamphetamine and characterised by depression , lethargy and headache. Games Movies TV Wikis. Journal of Medicinal Chemistry. Retrieved from ' http: Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. Remove the custom ad blocker rule s and the page will load as expected. See also Sympathomimetic amines. This page uses Creative Commons Licensed content from Wikipedia view authors.

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Methylenedioxypyrovalerone