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Synthetic cannabinoids — These are cannabinoid receptor agonists which produce effects similar to those of deltatetrahydrocannabinol THC , the principal psychoactive component in cannabis. Synthetic cannabinoids are often laced onto herbal products and sold as s pice, K2, Kronic, etc. Ketamine - A humanand veterinary anesthetic which acts as a stimulant at low doses and a hallucinogen at high doses. It is one of the most widespread NPS in Asia. Phenethylamines — This group contains substances related to amphetamine and methamphetamine, and generally produces stimulant effects. However, modification of these compounds can lead to potent hallucinogens such as Bromo-Dragonfly. Plant-based substances- This group includes plants with psychoactive properties. The most frequently reported are:. The leaves of the plant are chewed, resulting in the release of. Other substances — such as aminoindanes stimulants , phencyclidine-type substances hallucinogens and tryptamines hallucinogens. The use of NPS is often linked to health problems. NPS users have frequently been hospitalized with severe intoxications. There have also been a number of unexplained suicides associated with preceding use of synthetic cannabinoids spice. In addition, substances like 4-methylmethcathinone mephedrone , methylenedioxypyrovalerone MDPV , 4-methylamphetamine 4-MA have been associated with fatalities. UNODC research found substances, including ketamine, which were reported by Governments and laboratories around the world see box for the categories of NPS frequently sold. This figure is greater than the substances scheduled under the and Conventions. In February , five new substances were reported by drug analysis laboratories. Technically, the number of potential derivatives is unlimited. As long as there is no global monitoring mechanism on such substances, information on them will remain inconsistent. NPS are not under international control. Many countries have established permanent control measures for some substances or issued temporary bans. Only a handful of NPS have been reviewed by the mechanism established under the and Conventions. Responses in this area are likely to be most effective if they are coordinated across countries and regions. NPS are also a challenge for prevention and treatment. Instead of moral panic, objective and credible information is needed. In this respect, it is particularly important to create risk awareness among young people. Prevention measures should also target experienced drug users. Future plans include the development of an online knowledge hub for NPS which will be accessible to policy-makers and experts to find out the most relevant facts about certain NPS. Forensic information is essential and laboratories play a key role in identifying NPS. Accurate identification of NPS is a challenge and there is a need to improve information sharing on validated identification techniques. As part of addressing this challenge, UNODC has therefore been working on manuals on the identification of synthetic cannabinoids, synthetic cathinones and piperazines which are expected to be published in Home About. Categories of NPS sold in the market: Synthetic cannabinoids — These are cannabinoid receptor agonists which produce effects similar to those of deltatetrahydrocannabinol THC , the principal psychoactive component in cannabis. The most commonly reported members of this group are benzylpiperazine BZP and mCPP 1- 3-chlorophenyl piperazine Plant-based substances- This group includes plants with psychoactive properties. The most frequently reported are: - Kratom mitragyna speciosa Korth , a plant indigenous to South-East Asia that contains the alkaloid mitragyne; a stimulant at low doses and sedative at high doses. The leaves of the plant are chewed, resulting in the release of the stimulants cathinone and cathine. What are the risks of NPS? How widespread are NPS? What is the legal situation? How can I find out more about NPS? What are NPS?

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