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Cytostatic or antineoplastic drugs are mainly used in chemotherapy for cancer treatment. The daily use of cytostatic drugs by healthcare professionals might expose them to several health risks. Our study aims to monitor occupational and environmental exposure to cytostatic drugs among health care workers and predict its health risks. We first launched in Morocco an online survey to assess knowledge and practices related to the use of personal protective equipment among health professionals. Then, we conducted a pilot cross-sectional study among 45 health workers to identify methods for exposure evaluation and to quantitatively evaluate the exposure to cytostatics. Wipe sampling is taken from surfaces, objects and PPEs, and combined with dermal sampling from health care workers, to be analyzed by high performance liquid chromatography coupled with a mass spectrometer. Human biomonitoring focuses on the investigation of 6 cytostatics excreted in urine. Neurotoxicological and epigenetic biomarkers are assessed and correlated to cytostatics concentrations. The results show that Results are expected to highlight the risks of unintended exposure to cytostatic drugs in occupational setting and pave the way for a larger study confirming our preliminary results. Our pilot study should also lead to greater awareness raising and tailored occupational health programs. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide. Sign In or Create an Account. Sign in through your institution. Disability assessment. Assessment for capacity to work. Assessment of functional capability. Fitness for work. Civil service, central government, and education establishments. Construction industry. Emergency Medical Services. Fire and rescue service. Healthcare workers. Hyperbaric medicine. Military - Other. Military - Fitness for Work. Military - Mental Health. Oil and gas industry. Police service. Rail and Roads. Remote medicine. Telecommunications industry. The disabled worker. The older worker. The young worker. Travel medicine. Women at work. Framework for practice. Health and Safety at Work etc. Act and associated regulations. Health information and reporting. Ill health retirement. Questionnaire Reviews. Occupational Medicine. Blood borne viruses and other immune disorders. Dermatological disorders. Endocrine disorders. Gastrointestinal and liver disorders. Haematological disorders. Mental health. Neurological disorders. Occupational cancers. Renal and urological disorders. Respiratory Disorders. Rheumatological disorders. Chronic disease. Mental health rehabilitation. Motivation for work. Physical health rehabilitation. Workplace hazard and risk. Dusts and particles. Occupational stress. Post-traumatic stress. Browse all content Browse content in. Advanced Search. Search Menu. Article Navigation. Close mobile search navigation Article Navigation. Volume Article Contents Abstract. Journal Article. Hala Chetouani , Hala Chetouani. Oxford Academic. Google Scholar. Aziza Menouni. Omaima El Bouazzi. Higher institute of nursing professions and health techniques of Meknes. Imane Berni. Higher institute of nursing professions and health techniques of Laayoune. Lode Godderis. Samir El Jaafari. Select Format Select format. Permissions Icon Permissions. Abstract Introduction. All rights reserved. For commercial re-use, please contact reprints oup. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site-for further information please contact journals. Issue Section:. Download all slides. Views More metrics information. Total Views Email alerts Article activity alert. Advance article alerts. New issue alert. Subject alert. Receive exclusive offers and updates from Oxford Academic. Citing articles via Google Scholar. A novel approach to peer support for academic researchers. Exposure to procedural ionizing radiation and cancer risk among physicians. Former jean sandblasters die younger. Occupational well-being of diplomatic personnel: a qualitative study. More from Oxford Academic. Medicine and Health. Authoring Open access Purchasing Institutional account management Rights and permissions. Get help with access Accessibility Contact us Advertising Media enquiries.

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