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MDMA (Ecstasy) Abuse

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When most people hear MDMA , they think of illicit and adulterated preparations of the club drug sold as Molly or ecstasy. In reality, however, these street versions often contain adulterants and little or no of the active ingredient 3,4-methylenedioxymethamphetamine MDMA. Although ecstasy has been linked to long-term neurological effects and even death—associations that some experts dispute—MDMA has proven safe and non-addictive in some clinical studies. Post-traumatic stress disorder PTSD is a disorder that results from exposure to a traumatic experience like a life-threatening event, natural disaster, or violence. They also experience mood alterations, trouble sleeping, and more. Additionally, psychotherapy including prolonged exposure and cognitive-processing therapy have proven effective in treating people with PTSD; however, many people end up dropping out of psychotherapy. For people with PTSD, psychotherapy can be difficult because psychotherapy requires a patient to recall the triggering event. Some experts claim that MDMA administered before psychotherapy can reduce anxiety, reduce hypervigilance and increase relaxation all while keeping the patient motivated and engaged. MDMA can increase empathy between a patient and therapist and inspire the patient to think about their problems in new and innovative ways thus contributing to insight. According to Ben Sessa and David Nutt, authors of an article titled 'Making a medicine out of MDMA,' during psychotherapy, MDMA helps 'the patient to reach a position of empathic understanding and compassionate regard is part of their resolution and remittance of symptoms. Specifically, MDMA affects serotonin, dopamine and alpha-2 receptors as well as increasing the release of oxytocin. This release of oxytocin may facilitate bonding and empathy. Of note, this study was low power with few participants. We should take a moment to further distinguish the illicit use of ecstasy with the clinical use of MDMA. When people purchase ecstasy for recreational use, they typically use the drug excessively, expose themselves to potentially harmful adulterants and use other drugs in addition to MDMA like cocaine, marijuana , and alcohol. In clinical settings, limited doses of unadulterated MDMA are used for short-term adjuvant treatment during psychotherapy. In other words, buying ecstasy or off the street or in some club and using it to treat PTSD is a very bad idea. Specifically, both the United States and the United Kingdom have banned the drug. Learn the best ways to manage stress and negativity in your life. Nutt, David and Sessa, Ben. Sessa, Ben. Progress in Neurology and Psychiatry, Post-Traumatic Stress Disorder. Was this page helpful? Thanks for your feedback! Sign Up. What are your concerns? Article Sources. Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Related Articles. Behavioral Activation Treatment May Help. Verywell Mind uses cookies to provide you with a great user experience. By using Verywell Mind, you accept our.