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MDMA (Molly/Ecstasy) Dosage

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Get the latest information from CDC Coronavirus. MDMA is a synthetic drug that acts as a stimulant and hallucinogen. It has also been described as an entactogen—a drug that can increase self-awareness and empathy. Adulterants found in ecstasy tablets purchased on the street have included methamphetamine, the anesthetic ketamine, caffeine, the diet drug ephedrine, 20 the over-the-counter cough suppressant dextromethorphan, 21,22 heroin, phencyclidine PCP , and cocaine. Some people mistakenly believe that Molly does not contain contaminants often found in ecstasy. In fact, chemical analyses of drugs sold as Molly and seized by the U. When MDMA is taken in tablet or capsule form, a person begins feeling the effects 45 minutes later, on average. These effects peak 15 to 30 minutes after they are first felt and last an average of 3 hours, 27 though side effects could be experienced up to days later. National Institute on Drug Abuse website. September 26, This series of reports simplifies the science of research findings for the educated lay public, legislators, educational groups, and practitioners. The series reports on research findings of national interest. Skip to main content. COVID is an emerging, rapidly evolving situation. What is MDMA? Prev Index Next. What is the history of MDMA? Who is using MDMA? What are the effects of MDMA? Can MDMA use during pregnancy harm the baby? How can MDMA use be prevented? How are MDMA use disorders treated? Ordering Publications Call or:. Cite this article. Featured Publications. Opioids: Facts Parents Need to Know. Opioid Facts for Teens.

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This advice applies if you are determined to take MDMA. Guideline: More conservatively, 1. Low doses may be particularly important for your first few uses, as you might unknowingly have a health condition like malignant hyperthermia that makes MDMA more dangerous. A study found that MDMA desirable effects are maximized, and undesirable effects minimized, at doses between mg. This dosage advice is only relevant if you actually have MDMA! Fake MDMA substances like methylone have weaker effects per milligram. If using tablets: Look up your pill and see if you can figure out the dosage content. RollSafe knows that many people will choose not to follow this dosage advice. Lower dosages help reduce neurotoxicity risk, help increase enjoyment, and help reduce the risk of serious adverse effects. I think MDMA may well be neurotoxic at the higher end of recreational doses. Just my opinion. Studies by MAPS have looked for changes in mental abilities after people participated in their studies, with some participants receiving mg followed by As a result, I tend to think 1. So I would personally suggest 1. Interestingly, MAPS is seeing preliminary evidence that lower doses might be more therapeutic, which is consistent with observations by therapist Leo Zeff that people want higher doses than they need. From the fantastic book Acid Test. That point came at 2. Eight doses of that size were administered over four months one dose every two weeks , after which there was no detectable damage to neurons. Rick was greatly relieved, since that would be the key to persuading the FDA that it would be safe enough to conduct human therapeutic trials. I would be unsurprised if many of the MDMA-related deaths occur in people with contraindicated health conditions, i. Though it is important to note that some people may have a contraindicated condition and not realize it. How do you know? Higher doses are more likely to cause neurotoxicity. Higher doses are more likely to lead to serious adverse effects, including the possibility of MDMA-related death. We have not heard of any deaths related to taking pure MDMA at a dosage of less than mg. RollSafe does not support the Erowid dosage advice - it is too high for users that care about their health. Avoid taking any booster doses or redoses if possible. Read more on testing. Always re-set your dosage with a new source. Desirable effects are maximized between mg A study found that MDMA desirable effects are maximized, and undesirable effects minimized, at doses between mg. Really, everyone should buy a test kit. Higher doses are less safe Higher doses are more likely to cause neurotoxicity. Buy a 1 mg scale. Use a spoon or similar to put little bits of MDMA onto the playing card, until it reaches your safe dosage. Put the folded edge of the card up to the capsule, and tap it until the MDMA is inside the capsule. This is why it helps if it is folded. New to RollSafe. Start here.

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