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The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals. By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution. Institute of Fine Chemical Technologies named after M. Immunochromatographic analysis of determination of narcotic substances using test systems containing gold nanoparticles, on the example of morphine and amphetamine. Podzhilkova , S. Eremin , S. Journal: Sudebno-Meditsinskaya Ekspertisa. DOI: Sudebno-Meditsinskaya Ekspertisa. In Russ. Currently, there is a constant expansion of the range of narcotic substances that differ from each other by a small structural fragment. The option of determining narcotic substances using test panels is widespread due to its rapidity and high specificity through the use of immunochemical reactions. The purpose of the study was to optimize the determination of morphine and amphetamine in bioobjects synthetic and natural urine using immunochromatographic analysis with new test panels and to select the optimal conditions for mass analysis. Test panels were used to detect the presence of amphetamine and morphine. For color recording of the results of analysis, colloidal gold nanoparticles were used. The principle of operation of these test panels is described. The sensitivity of the test panels is such that it is possible to avoid false-positive results. The analytical characteristics of the developed metho-dology were determined: detection limit, precision, truth and specificity. The specificity was proved by conducting ICA to detect the presence of cross-reactions of test systems to amphetamine and morphine using structural analogues — adrenaline and codeine , respectively. The study did not receive false positive results for these molecules using the proposed test panels. Immunochromatographic test systems are optimal for drug detection, especially when conducting mass studies. An email was sent to test gmail. Follow the link from the letter to complete the registration on the site. You can become an author of one of our magazines, send a request and we will consider it in during the day. We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. All journals. Очистить поле. Search result: 0. Views: Downloaded: Contact the author. Table of contents. To cite this article:. Forgot Password? Last Name. Save Cancel. I agree.

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