Like Mom Like Me

Like Mom Like Me




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Like Mom Like Me
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Like Mom, Like Me
(1978 TV Movie)










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A professor's (Linda Lavin) husband deserts her and her teenage daughter (Kristy McNichol), leaving them open to romance.



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by Sari N. Harrar Published: Nov 3, 2011
Sarí N. Harrar, former health news editor at Prevention , is a freelance writer specializing in health, science, and medicine.
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Here's what you need to know about genetic diseases
If your mom has been diagnosed with cancer, heart disease, diabetes, or some other health problem with a genetic link, you may wonder if you'll get the same diagnosis one day. "When it comes to breast cancer in particular, many women look at their mother's experience" for a preview of their own, says Michael Thun, MD, an epidemiological researcher with the Atlanta-based American Cancer Society (ACS). "But if that's all you look at, you're missing more than half the picture."
For starters, you're missing your father's 50% contribution to your genetic makeup. And you're overlooking the role that lifestyle plays. Whether you smoke, eat your fruits and vegetables, exercise regularly, and get screening tests all affect your odds of developing cancer, heart disease , and other health problems.
But if you're worried about your health inheritance, there are a few things you should know and do.
Your Risk Having a distant relative, such as a cousin or great-grandmother, with breast cancer slightly increases the average one-in-eight lifetime risk of getting the disease. But having a first-degree relative with breast cancer (your mom, sister, or daughter—or father, brother, or son, since men can also get breast cancer) can double the risk. The risk is even higher if that relative was diagnosed before age 50. And having two first-degree relatives can boost the odds as much as threefold.
In some families, the culprit is a mutation or glitch in the genes known as BRCA1 and BRCA2, which you can inherit from your mom or dad and that may also increase your risk of ovarian cancer . Of the 1 in 200 women with a mutation, about 50 to 80% will develop breast cancer.
Improve Your Odds Even if you don't have a family history, there's some evidence that staying close to your ideal weight, exercising, eating lots of produce and little fat, and having no more than one alcoholic drink a day may help you avoid breast cancer, says Debbie Saslow, PhD, the ACS's director of breast and gynecologic cancers. If you have a strong family history of breast cancer (more than one close relative with it), you should also follow this advice:
Your Risk Susan Gilbert's mother died of colon cancer at age 51. Gilbert, a motivational speaker and author in San Diego, is now 51 herself. She knows that having a first-degree relative with the disease puts her at a somewhat higher lifetime risk: about 6%. (The average American's risk is 2%.) 
If her mother had been diagnosed before age 45, Gilbert's risk would have risen to 10%. It's about 17% for women who have two first-degree relatives with the disease. Women with a family history of ovarian, uterine, or breast cancer are also at higher risk.[pagebreak]Those at very high risk, however, are people with one of two syndromes caused by genetic mutations: familial adenomatous polyposis syndrome (FAP) or hereditary nonpolyposis colon cancer (HNPCC). People with FAP develop hundreds of precancerous polyps or growths in their colons and are virtually guaranteed to get colorectal cancer unless they have their colons removed in early adulthood, explains Durado Brooks, MD, the ACS's director for colon cancer. Those with HNPCC run a 70 to 80% chance of developing colon cancer.
Improve Your Odds Once again, there are things everyone should do to lower his or her risk of colon cancer. "Eating a low-fat, low-meat, high-vegetable diet, getting regular physical activity, and avoiding obesity and cigarettes are all good ideas," Dr. Brooks says. Gilbert eats a low-fat diet and maintains her lean figure by running (she's a marathoner). There's also some evidence that calcium supplements and about 400 micrograms (mcg) of folic acid daily may lower risk.
If you're at increased risk of colon cancer, you should also do the following: 
Your Risk Connie McDowell, 53, a social worker from Coopersburg, PA, is working hard to not be like her mother, who has type 2 diabetes. "I eat small meals several times a day, and I watch my fat and sugar intake," she says. She also exercises regularly. 
In type 2 diabetes (the most common form), your body stops responding to insulin, the hormone that delivers sugar into cells, and it does not produce enough insulin to overcome this problem. The result: soaring insulin levels. Diabetes can quadruple the risk of heart disease and raise your risk for blindness, kidney failure, and even amputation.If you have a parent or sibling with the disease, your lifetime risk is about 38 percent; if both parents have it, your odds could soar as high as 80 percent. Many genes, singly or in combination, could be at work. "But genes don't cause diabetes," says Steven C. Elbein, MD, professor of medicine and program director of the General Clinical Research Center at the University of Arkansas Medical School in Little Rock. "They increase the likelihood you'll get it. There's a powerful interplay between lifestyle risk (being overweight, not exercising, carrying excess abdominal fat) and genetic risk."
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