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Купить онлайн закладку Acheter de la methamphetamine en Saguenay: мефедрон, амфетамин, спайс, кокаин, мдма, героин, марихуана
Long-term methamphetamine abuse has many negative consequences, including addiction. Addiction is a chronic, relapsing disease, characterized by compulsive drug seeking and use and accompanied by functional and molecular changes in the brain. Abusers often need to take higher doses of the drug, take it more frequently, or change how they take it in an effort to get the desired effect. Chronic methamphetamine abusers may develop difficulty feeling any pleasure other than that provided by the drug, fueling further abuse. Withdrawal from methamphetamine occurs when a chronic abuser stops taking the drug; symptoms of withdrawal include depression, anxiety, fatigue, and an intense craving for the drug. In addition to being addicted to methamphetamine, chronic abusers may exhibit symptoms that can include significant anxiety, confusion, insomnia, mood disturbances, and violent behavior. They also may display a number of psychotic features, including paranoia, visual and auditory hallucinations, and delusions for example, the sensation of insects creeping under the skin. Psychotic symptoms can sometimes last for months or years after a person has quit abusing methamphetamine, and stress has been shown to precipitate spontaneous recurrence of methamphetamine psychosis in formerly psychotic methamphetamine abusers. These and other problems reflect significant changes in the brain caused by abuse of methamphetamine. Neuroimaging studies have demonstrated alterations in the activity of the dopamine system that are associated with reduced motor speed and impaired verbal learning. Studies in chronic methamphetamine abusers have also revealed severe structural and functional changes in areas of the brain associated with emotion and memory, which may account for many of the emotional and cognitive problems observed in chronic methamphetamine abusers. Methamphetamine abuse also has been shown to have negative effects on non-neural brain cells called microglia. These cells support brain health by defending the brain against infectious agents and removing damaged neurons. Too much activity of the microglial cells, however, can assault healthy neurons. A study using brain imaging found more than double the levels of microglial cells in former methamphetamine abusers compared to people with no history of methamphetamine abuse, which could explain some of the neurotoxic effects of methamphetamine. Some of the neurobiological effects of chronic methamphetamine abuse appear to be at least partially reversible. Another neuroimaging study showed neuronal recovery in some brain regions following prolonged abstinence 14 but not 6 months. This recovery was associated with improved performance on motor and verbal memory tests. But function in other brain regions did not recover even after 14 months of abstinence, indicating that some methamphetamineinduced changes are very long lasting. The dental problems may be caused by a combination of poor nutrition and dental hygiene as well as dry mouth and teeth grinding caused by the drug. Skin sores are the result of picking and scratching the skin to get rid of insects imagined to be crawling under it. National Institute on Drug Abuse website. This series of reports simplifies the science of research findings for the educated lay public, legislators, educational groups, and practitioners. The series reports on research findings of national interest. Skip to main content. What are the long-term effects of methamphetamine abuse? Recovery of Brain Dopamine Transporters in Chronic Methamphetamine METH Abusers Methamphetamine abuse greatly reduces the binding of dopamine to dopamine transporters highlighted in red and green in the striatum, a brain area important in memory and movement. With prolonged abstinence, dopamine transporters in this area can be restored. Long-term effects may include: Contents Letter from the Director What is methamphetamine? What is the scope of methamphetamine abuse in the United States? How is methamphetamine abused? How is methamphetamine manufactured? How is methamphetamine different from other stimulants, such as cocaine? What are the immediate short-term effects of methamphetamine abuse? What are the risks of methamphetamine abuse during pregnancy? What treatments are effective for people who abuse methamphetamine? Where can I get further information about methamphetamine? Ordering Publications Call or: Opioid Facts for Teens. Drugs, Brains, and Behavior: The Science of Addiction. Facts Parents Need to Know.
Купить онлайн закладку Acheter de la methamphetamine en Saguenay: мефедрон, амфетамин, спайс, кокаин, мдма, героин, марихуана
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Купить онлайн закладку Acheter de la methamphetamine en Saguenay: мефедрон, амфетамин, спайс, кокаин, мдма, героин, марихуана
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Купить онлайн закладку Acheter de la methamphetamine en Saguenay: мефедрон, амфетамин, спайс, кокаин, мдма, героин, марихуана
Купить онлайн закладку Acheter de la methamphetamine en Saguenay: мефедрон, амфетамин, спайс, кокаин, мдма, героин, марихуана