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Although they have a lot in common, amphetamines and methamphetamines are not the same drug. Each one acts differently on the body and the mind. Meth is manufactured by using its parent drug, amphetamine. Over the last decade, methamphetamine has received a large amount of publicity throughout the world. Most of the publicity was about the heavy abuse and addictions caused by the drug. Amphetamine has been around for a long time and has been prescribed by doctors and can be found in various medications. While both are addicting, methamphetamine has become more popular amongst abusers. It was around that time, medical professionals discovered the benefits of amphetamines. They learned that the drug widened airways, and therefore could treat asthma, allergies, and colds. It was also discovered that amphetamines helped people stay awake and alert and was given to soldiers during the war. The drug was available legally and was being purchased by housewives and other people who sought the effects of the increased energy and suppressing of the appetite that amphetamine provided. Today, a prescription containing amphetamines may be given to people with narcolepsy and ADHD. Methamphetamine is a derivative of amphetamine. Eventually it began to be heavily used by people, especially those working in the trucking industry. Both raise the levels of norepinephrine and dopamine in the brain. When these chemicals are increased, a person will feel a sense of euphoria and an increase in energy. The main difference between amphetamine and methamphetamine involves a bit of chemistry. The easiest way to explain this is as follows. Both drugs are stimulants of the central nervous system. However, amphetamine is chemically phenylethylamine, while methamphetamine is referred to as N-methylamphetamine. Methamphetamine breaks down into amphetamine when it is metabolised. Amphetamines Methamphetamine and Amphetamines. Although methamphetamine MA and other amphetamines can have similar effects, differences also exist. For example, MA has longer lasting and more toxic effects than amphetamine. In addition, compared with amphetamine, MA has greater activity as a central nervous system CNS stimulant while having less peripheral nervous system and cardiovascular stimulation activity. Another difference between amphetamine and MA is that amphetamine stimulates the CNS indirectly by activating the release of catecholamines and inhibiting their breakdown and storage. In contrast, MA stimulates the postsynaptic catecholamine receptors directly. They are almost indistinguishable when used in moderate doses. However there are a few differences. Neither is particularly harmful when used in moderation. Instead of essentially repeating a few of the good answers here, I would like to point out that ROA route of admin. For instance IV, and smoking allow the compound to cross the blood brain barrier within seconds compared to oral amphetamine e. The core molecular structure is unchanged, except of course for the substituted -CH3 group on the terminal amine. A lot of people have given you technical answers, spot on and complete. For the layman, the difference is potency, duration and crash. Amphetamine is extremely pleasurable to most people, yet still functional at a normal dose. Methamphetamine is so extremely pleasurable as to completely floor the user to the extent of a spiritual experience if injected. The duration is so god-awful long that redosing usually ends in a psychotic break from lack of sleep and nuerological imbalances severe enough to induce suicidal depression result upon crash. The main difference between amphetamine and methamphetamine is the methyl group on methamphetaime it looks like the little line on the right had side of the graphic. These two differences result in all the stronger behavioral and addictive profiles of the drug. Amphetamine is the name for a specific type of chemical that can stimulate the central nervous system. Methamphetamine and dextroamphetamine are types of amphetamines. Because they have chemical structures similar to amphetamine, they cause the same general effects on the body. Ask New Question Sign In. How do amphetamine and methamphetamine differ? The Difference The main difference between amphetamine and methamphetamine involves a bit of chemistry. Thanks to Google for my reference and my bright fingers. Related Questions More Answers Below Which is the most dangerous methamphetamine, amphetamine or methylphetamine? What are the differences between Phentermine Adipex and crystal methamphetamine? Are Adderall and meth the same? How does one convert amphetamine to methamphetamine? How would we convert methamphetamine to amphetamine? Methamphetamine and Amphetamines Methamphetamine and Amphetamines Although methamphetamine MA and other amphetamines can have similar effects, differences also exist. Quora User , Likes to get high when traveling abroad. The primary difference is the extra methyl group CH3 attached to benzene ring of the molecule. This makes the molecule more lipid soluble, thus getting more molecules of methamphetamine across the blood-brain barrier than amphetamine in the same amount of time. Once this occurs, methamphetamine is metabolized into amphetamine, and further metabolized into other constituents. The effects are a more potent drug, a stronger rush, a stronger high, and often a proportional increase in side effects. Thank you for your feedback! Answered Oct 14, Answered Feb 17, Methamphetamine has an easier time crossing the blood-brain-barrier, so it gets to the brain quickly. Methamphetamine has serotonergic effects, making it more toxic in overdose. The hydrochloride salt of methamphetamine, commonly known as crystal meth, has a lower boiling point, making it suitable for vaporization. Illicit amphetamine in Asia and America is usually methamphetamine, while in Europe it tends to be regular amphetamine. Meth will shatter glass. Put simply, methamphetamine is one type of amphetamine. Related Questions Are the negative effects of methamphetamine exaggerated? What are the ingredients for methamphetamine? Can amphetamine be a crystal? Are methamphetamine, methylphenidate and amphetamine all called speed drugs? How does one synthesise methamphetamine? What are the differences between crystal methamphetamine and methamphetamine? Is methamphetamine just amphetamine with an added methyl group? What is the difference between methamphetamine and diphenhydramine? What is amphetamine fatigue? Is the reaction of amphetamine with chloromethane a reliable method for synthesising methamphetamine? Is clear methamphetamine stronger? Can Adderall cause a Urine Test to show positive for methamphetamine? What are some differences in the way you feel when using good quality methamphetamine versus bad quality methamphetamine. Where can I find a good methamphetamine recipe? Still have a question? Related Questions Which is the most dangerous methamphetamine, amphetamine or methylphetamine? Are the negative effects of methamphetamine exaggerated?
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