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With long-term use, corticosteroids can result in any of the following side effects. Check with your doctor immediately if any of the following side effects occur while taking dexamethasone: More common. See this reference from the National Institutes of Health about how much calcium you need for your sex and age, and how to get as much as possible from diet. In some circumstances, prednisone can help pre-existing infections, particularly those caused by yeasts or fungi, to spread. You are suffering from any type of microbial infection. Smoking and alcohol increase the risk of osteoporosis, so limiting these is helpful. Most steroid side effects only occur when people take prednisone long-term. Side effects not requiring immediate medical attention. These androgens can become aromatized, which is the process by which the aromatase enzymemetabolizes androgens and converts them toestrogen. Frequency not reported : Decreased carbohydrate and glucose tolerance, increased requirements for insulin or oral hypoglycemic agents in diabetics, lipid abnormal, negative nitrogen balance caused by protein catabolism, hypokalemia, hypokalemic alkalosis, metabolic alkalosis, potassium loss, sodium retention with resulting edema, increased appetite and weight gain, anorexia and weight loss, hypertriglyceridemia, hypercholesterolemia \\\\\\\\\\\\\[Ref\\\\\\\\\\\\\] Cardiovascular. Topical steroids can also be given as: Eye drops to reduce inflammation on the surface of the eye such as caused by uveitis. Children taking prednisone are of special concern and require careful consideration. What you can do: Talk with your doctor about your personal risk. While topical steroids have enormous benefit in reducing inflammation, they can also come with certain side effects. Whitmore SE 'Dexamethasone injection-induced generalized dermatitis. What are the side effects of oral steroids?. 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