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Background: Evidence regarding MDMA ecstasy dependence and the most suitable criteria for its assessment are controversial. This study aimed to assess the prevalence of last year symptoms of dependence upon MDMA compared to cocaine, mephedrone and ketamine among a large global non-treatment seeking sample. Methods: A cross-sectional anonymous online survey was promoted by a UK-based dance music website between 15 November and 1 January Logistic regression models with Generalized Estimating Equations were used to compare dependence symptoms between groups. MDMA got the highest rating of pleasurable high mean 8. Conclusions: Our results highlight the self-reported dependence potential of MDMA but low desire to use less or get help. Abstract Background: Evidence regarding MDMA ecstasy dependence and the most suitable criteria for its assessment are controversial. Substances Methamphetamine Ketamine mephedrone N-Methyl-3,4-methylenedioxyamphetamine.
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