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Medically reviewed on Nov 5, Methadone is an opioid medication. An opioid is sometimes called a narcotic. Methadone reduces withdrawal symptoms in people addicted to heroin or other narcotic drugs without causing the 'high' associated with the drug addiction. Methadone is used as a pain reliever and as part of drug addiction detoxification and maintenance programs. It is available only from a certified pharmacy. You should not use methadone if you have severe asthma or breathing problems, or a blockage in your stomach or intestines. Keep the medication in a place where others cannot get to it. Taking opioid medicine during pregnancy may cause life-threatening withdrawal symptoms in the newborn. Fatal side effects can occur if you use opioid medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing. Methadone may cause a life-threatening heart rhythm disorder. Call your doctor at once if you have a headache with chest pain and severe dizziness , and fast or pounding heartbeats. Your heart function may need to be checked during treatment. If you use opioid medicine while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on opioids may need medical treatment for several weeks. Methadone can pass into breast milk and cause drowsiness, breathing problems, or death in a nursing baby. Follow the directions on your prescription label and read all medication guides. Never use methadone in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of methadone. Never share opioid medicine with another person, especially someone with a history of drug abuse or addiction. Selling or giving away opioid medicine is against the law. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device not a kitchen spoon. Dissolve the dispersible tablet in water, orange juice, or other citrus-flavored non-alcoholic beverage. Never use methadone tablets or liquid to make a mixture for injecting the drug into your vein. This practice has resulted in death with the misuse of prescription drugs. When methadone is used as part of a treatment program for drug addiction or detoxification, your doctor may recommend that your dose be given to you by a family member or other caregiver. You should not stop using this medicine suddenly. Store at room temperature away from moisture and heat. Keep track of your medicine. Methadone is a drug of abuse and you should be aware if anyone is using it improperly. Do not keep leftover opioid medication. Just one dose can cause death in someone using this medicine accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, flush the unused medicine down the toilet. Dosage Information in more detail. If you take methadone for pain: Take the missed dose as soon as you remember, then take your next dose 8 to 12 hours later. If you take methadone for drug addiction: Take your missed dose the next day at the regular time. If you miss your doses for longer than 3 days in a row, call your doctor for instructions. You may need to restart at a lower dose. Seek emergency medical attention or call the Poison Help line at An overdose can be fatal, especially in a child or other person using methadone without a prescription. Overdose symptoms may include slow heart rate , severe drowsiness, muscle weakness, cold and clammy skin, pinpoint pupils, very slow breathing, or coma. Avoid driving or operating machinery until you know how this medicine will affect you. Dizziness or severe drowsiness can cause falls, accidents, or severe injuries. Grapefruit may interact with methadone and lead to unwanted side effects. Avoid the use of grapefruit products. Get emergency medical help if you have signs of an allergic reaction to methadone: Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up. Seek medical attention right away if you have symptoms of serotonin syndrome, such as: Serious side effects may be more likely in older adults and those who are malnourished or debilitated. Long-term use of opioid medication may affect fertility ability to have children in men or women. It is not known whether opioid effects on fertility are permanent. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Side effects in more detail. You may have breathing problems or withdrawal symptoms if you start or stop taking certain other medicines. Tell your doctor if you also use an antibiotic , antifungal medication, heart or blood pressure medication, seizure medication, or medicine to treat HIV or hepatitis C. Opioid medication can interact with many other drugs and cause dangerous side effects or death. Be sure your doctor knows if you also use:. This list is not complete. Other drugs may interact with methadone, including prescription and over-the-counter medicines, vitamins , and herbal products. Not all possible interactions are listed here. Drug Interactions in more detail. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use methadone only for the indication prescribed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Methadose , Dolophine , Methadone Diskets. Pain tramadol , acetaminophen , Tylenol , naproxen , oxycodone , aspirin , ibuprofen , amitriptyline , More By clicking Subscribe, I agree to the Drugs. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices. Subscribe to receive email notifications whenever new articles are published. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. To view content sources and attributions, please refer to our editorial policy. We comply with the HONcode standard for trustworthy health information - verify here. Print this page Add to My Med List. Methadone Rating User Reviews 8. Subscribe to free Drugs. FDA alerts for all medications.

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