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Of these, around Opioids were the most harmful drug type and accounted for 70 per cent of the negative health impact associated with drug use disorders worldwide, according to the latest World Drug Report , released today by UNODC. Disorders related to the use of amphetamines also account for a considerable share of the global burden of disease. And while the market for new psychoactive substances NPS is still relatively small, users are unaware of the content and dosage of psychoactive substances in some NPS. This potentially exposes users to additional serious health risks. The Report finds that hepatitis C is causing the greatest harm among the estimated 12 million people who inject drugs worldwide. Out of this number, one in eight 1. Overall, three times more people who use drugs die from hepatitis C , than from HIV 60, However, the Report stresses that despite recent advances in the treatment of hepatitis C, access remains poor, as treatment remains very expensive in most countries. This year marks 20 years of the World Drug Report, which comes at a time when the international community has decided to move forward with joint action. UNODC Executive Director Yury Fedotov highlighted that the outcome document of the landmark UN General Assembly special session on the world drug problem contains more than concrete recommendations to reduce demand and supply, however he acknowledges that more needs to be done. In , transnational organized crime groups across the globe were estimated to have generated between one fifth and one third of their revenues from drug sales. Mobile communications offers new opportunities to traffickers, while the darknet allows users to anonymously buy drugs with a crypto-currency, such as bitcoin. While drug trafficking over the darknet remains small, there has been an increase in drug transactions, of some 50 per cent annually between September and January according to one study. Typical buyers are recreational users of cannabis, 'ecstasy', cocaine, hallucinogens and NPS. The spectrum of substances available on the drug market has widened considerably, the Report says. The opioid market in particular is becoming more diversified, with a combination of internationally controlled substances like heroin, and prescription medicines that are either diverted from the legal market or produced as counterfeit medicines. NPS continued to evolve such that by , the number of reported substances had nearly doubled to compared with NPS in Opium production is up and the cocaine market is thriving. In , global opium production increased by one third compared with the previous year and this was primarily due to higher opium poppy yields in Afghanistan. The Report also points to the expansion of the cocaine market, such that from , coca bush cultivation increased by 30 per cent mainly as a result of increased cultivation in Colombia. Following a period of decline, there are signs that cocaine use is increasing in the two largest markets, North America and Europe. Although not all terrorist groups depend on drug profits, some do. Up to 85 per cent of opium cultivation in Afghanistan occurs in territory under some influence of the Taliban. The World Drug Report provides a global overview of the supply and demand of opiates, cocaine, cannabis, amphetamine-type stimulants and new psychoactive substances NPS , as well as their impact on health. It highlights the scientific evidence for hepatitis C causing greatest harm among people who use drugs; and brings into view further diversification of the thriving drug market, as well as changing business models for drug trafficking and organized crime. Организация Объединенных Наций. Управление ООН по наркотикам и преступности. World Drug Report Changing business models for drug trafficking and organized crime In , transnational organized crime groups across the globe were estimated to have generated between one fifth and one third of their revenues from drug sales. Global Drug Market Trends The spectrum of substances available on the drug market has widened considerably, the Report says. Drugs and terrorism Although not all terrorist groups depend on drug profits, some do.